ADC Linker

Cat. No.	Product Name	Effect	Purity

• HY-W019543

  Disuccinimidyl suberate Crosslinker
  Disuccinimidyl suberate Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-20336

  Mc-Val-Cit-PABC-PNP
  Mc-Val-Cit-PABC-PNP is a cathepsin cleavable linker for antibody-drug conjugates (ADCs) which couples the antibody element to the effecting compound. Mc-Val-Cit-PABC-PNP can be used in the synthesis of ADCs[1][2].

• HY-42973

  DBCO-NHS ester		99.53%
  DBCO-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-D0975

  Sulfo-SMCC sodium
  Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.

• HY-114697

  DSG Crosslinker
  DSG Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-173633

  BrAc-Val-Ala
  BrAc-Val-Ala is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as ABBV-969[1].

• HY-400191A

  Fmoc-Gly-Gly-allyl propionate
  Fmoc-Gly-Gly-allyl propionate is a cleavable linker that can be used to synthesize Antibody-Drug Conjugates (ADCs)[1].

• HY-173635

  Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB
  Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB is an interchain cysteines to a Maleimide-reactive, β-glucuronidase-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as AZD0516 (HY-173639)[1].

• HY-130524

  Amino-PEG4-CH2COOH
  Amino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Amino-PEG4-CH2COOH is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

• HY-126498

  PDEC-NB		99.88%
  PDEC-NB is a disulfide cleavable linker used for the antibody-drug conjugate (ADC).

• HY-W591374

  DBCO-PEG4-Val-Ala-PAB-PNP
  DBCO-PEG4-Val-Ala-PAB-PNP is a cleavable ADC linker. The Val-Ala linkers can be cleaved by Cathepsin B. The DBCO groups is commonly used for Click Chemistry reactions. PEG spacer improves the compound's aqueous solubility. PNP is a good leaving group.

• HY-126958

  Biotin-PEG2-acid
  Biotin-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Biotin-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

• HY-130167

  Fmoc-NH-PEG9-CH2CH2COOH
  Fmoc-NH-PEG9-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG9-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-126674

  Mal-Phe-C4-Val-Cit-PAB-DMEA
  Mal-Phe-C4-Val-Cit-PAB-DMEA is a cleavable ADC linker containing a Maleimide group. Mal-Phe-C4-Val-Cit-PAB-DMEA is used for making antibody-drug conjugate.

• HY-157008

  (S)-TCO-PEG2-Maleimide
  (S)-TCO-PEG2-Maleimide is an ADC linker containing 2 PEG units. (S)-TCO-PEG2-Maleimide can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.

• HY-156307

  Me-Tet-PEG3-Maleimide
  Me-Tet-PEG3-Maleimide is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.

• HY-126509

  Mal-amido-PEG10-C2-​NHS ester
  Mal-amido-PEG10-C2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2].

• HY-151837

  H-L-Phe(4-NH-Poc)-OH hydrochloride
  H-L-Phe(4-NH-Poc)-OH (hydrochloride) is a click chemistry reagent containing an azide group. Used as a modified Phe or Tyr analogue in protein and peptide biosynthesis. Propargyloxycarbonyl, commonly abbreviated as Poc or Pryoc, can either be used as alkyne component for standard Click conjugation or in combination with tetrazine linkers in copper-free Diels-Alder type Click reactions. It also has applications as unusual protecting group for amines, hydroxy functions and as esters. All 3 are stable to neat TFA, but can be cleaved at ambient temperature with Co2(CO)8 in TFA:DCM. Deprotection with other transition metals like palladium have also been reported[1][2]. H-L-Phe(4-NH-Poc)-OH (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-151783

  DAPOA
  DAPOA is a click chemistry reagent containing an azide group. DAPOA can be used in peptide synthesis as a linker that can be further modified at the azido-groups using Staudinger ligation or click-chemistry[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-136133

  NHS-PEG2-SS-PEG2-NHS		98.03%
  NHS-PEG2-SS-PEG2-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-136051

  Biotin-PEG3-aldehyde
  Biotin-PEG3-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151846

  Boc-L-Pra-OH (DCHA)
  Boc-L-Pra-OH (DCHA) is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1].

• HY-140121

  m-PEG6-SS-PEG6-methyl
  m-PEG6-SS-PEG6-methyl is a cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-136033

  Methyltetrazine-SS-NHS
  Methyltetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Methyltetrazine-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-129655

  Sulfo-SMPB sodium
  Sulfo-SMPB sodium is a non-cleavable, heterobifunctional chemical cross-linking reagent which contains N-hydroxysuccinimide (NHS) ester and maleimide groups, allowing covalent conjugation of amine- and sulfhydryl-containing molecules[1].

• HY-130690

  Propargyl-PEG1-SS-PEG1-C2-Boc
  Propargyl-PEG1-SS-PEG1-C2-Boc is a Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG1-SS-PEG1-C2-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG1-SS-PEG1-C2-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-135859

  NH2-MPAA-NODA
  NH2-MPAA-NODA is a nitroveratryl-based photocleavable linker, it has a NODA motif and a methyl phenyl acetic acid (MPAA) backbone[1]. NH2-MPAA-NODA can be used as a radiolabel by labeling with 18F-fluoride.

• HY-78931

  Boc-Dap-NE
  Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.

• HY-126974

  Propargyl-PEG3-NHS ester
  Propargyl-PEG3-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG3-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-P1449

  Boc-Gly-Gly-Phe-Gly-OH
  Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).

• HY-130485

  Bromo-PEG2-C2-azide
  Bromo-PEG2-C2-azide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Bromo-PEG2-C2-azide is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromo-PEG2-C2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-131157

  Lys(MMT)-PAB-oxydiacetamide-PEG8-N3
  Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 is a cleavable antibody agent conjugate linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-130474

  Azido-PEG6-NHS ester
  Azido-PEG6-NHS ester is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG6-NHS ester is also a PEG- and Alkyl/ether based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG6-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-130934

  TCO-PEG1-Val-Cit-OH
  TCO-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. TCO-PEG1-Val-Cit-OH is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

• HY-140987

  5-Maleimidovaleric acid
  5-Maleimidovaleric acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-141151

  Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB
  Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-140150

  Azido-PEG3-Val-Cit-PAB-PNP		99.09%
  Azido-PEG3-Val-Cit-PAB-PNP is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG3-Val-Cit-PAB-PNP is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG3-Val-Cit-PAB-PNP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-140215

  Azido-PEG6-amine
  Azido-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG6-amine is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. Azido-PEG6-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-136058

  N3-PEG4-amido-Lys(Fmoc)-acid
  N3-PEG4-amido-Lys(Fmoc)-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. N3-PEG4-amido-Lys(Fmoc)-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-130956

  Boc-NMe-Val-Val-Dil-Dap-OH
  Boc-NMe-Val-Val-Dil-Dap-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-151640

  Fmoc-DAP-N3
  Fmoc-DAP-N3 is a click chemistry reagent containing an azide group. Fmoc-DAP-N3 is a short, linear spacer molecule with Fmoc protected amino function. Fmoc-DAP-N3 can be used in click conjugation and amid bond formation either with small molecules or for bioconjugation with proteins and antibodies[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-172290

  Benzyl N1-[PEG1-NHS]-N6-(t-Boc)-L-lysinate
  Benzyl N1-[PEG1-NHS] -N6-(t-Boc)-L-lysinate is a multifunctional ADC linker consisting of a terminal benzyl group, one PEG unit, an NHS ester, and a t-Boc-protected L-lysine, often used for bioconjugation and chemical modifications in R&D.

• HY-140313

  Methyltetrazine-DBCO
  Methyltetrazine-DBCO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Methyltetrazine-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Methyltetrazine-DBCO also contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-136099

  Bocaminooxyacetamide-PEG2-Azido
  Bocaminooxyacetamide-PEG2-Azido is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Bocaminooxyacetamide-PEG2-Azido is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-126353

  Fmoc-Val-Ala-PAB-OH		99.88%
  Fmoc-Val-Ala-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-W125504

  AEEA-AEEA
  AEEA-AEEA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). AEEA-AEEA is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

• HY-145735

  Allyl (2-aminoethyl)carbamate
  Allyl (2-aminoethyl)carbamate is a cleavable linker.

• HY-W040236

  m-PEG8-Amine
  m-PEG8-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-136044

  APN-PEG4-BCN
  APN-PEG4-BCN is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. APN-PEG4-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-W105531

  Fmoc-Ala-Ala-Pro-OH
  Fmoc-Ala-Ala-Pro-OH is a F-moc protected tripeptide linker which may be employed in the creation of antibody drug conjugates (ADCs).

• HY-118764

  Propargyl-PEG2-acid
  Propargyl-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG2-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-151675

  H-L-Tyr(3-N3)-OH
  H-L-Tyr(3-N3)-OH is a click chemistry reagent containing an azide[1]. H-L-Tyr(3-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-126508

  Mal-amido-PEG5-C2-​NHS ester
  Mal-amido-PEG10-C2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2]

• HY-79369S

  Succinic anhydride-d4
  Succinic anhydride-d4 is the deuterium labeled Succinic anhydride. Succinic anhydride is a cyclic anhydride and a nonclaevable ADC linker extracted from patent WO2009064913A1. Succinic anhydride can react with compound 4 of the patent to link the proagent to an amine or hydroxy 1 group of a targeting polypeptide[1].

• HY-140149

  Azido-PEG4-Val-Cit-PAB-OH
  Azido-PEG4-Val-Cit-PAB-OH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG4-Val-Cit-PAB-OH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG4-Val-Cit-PAB-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-140501

  m-PEG11-acid
  m-PEG11-acid is a non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. m-PEG11-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].

• HY-140309

  Gly-Gly-Gly-PEG4-DBCO		98.35%
  Gly-Gly-Gly-PEG4-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Gly-Gly-Gly-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-151859

  N3-Gly-Gly-OH		98.40%
  N3-Gly-Gly-OH is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-120702

  N-Boc-PEG5-bromide
  N-Boc-PEG5-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG5-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-W006445

  N-Boc-PEG2-bromide
  N-Boc-PEG2-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG2-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-Y0530

  Azetidine-3-carboxylic acid
  Azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2

• HY-131156

  Mal-PEG2-Val-Cit-PABA-PNP
  Mal-PEG2-Val-Cit-PABA-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130165

  Tr-PEG8-OH
  Tr-PEG8-OH is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Tr-PEG8-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

• HY-136309

  Ald-PEG23-SPDP
  Ald-PEG23-SPDP is a cleavable 23 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151660

  Fmoc-D-Lys(N3)-OH
  Fmoc-D-Lys(N3)-OH is a click chemistry reagent containing an azide group. Fmoc-D-Lys(N3)-OH can be used for the research of various biochemical[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-400677

  NH2-PEG4-GGFG-NH-CH2-O-CH2COOH
  NH2-PEG4-GGFG-NH-CH2-O-CH2COOH is a reactant for the synthesis of ADC linkers and is used to synthesize Antibody-Drug Conjugates (ADCs)[1].

• HY-42146

  BMPS
  BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-130110

  Sulfo-DMAC-SPP
  Sulfo-DMAC-SPP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-141190

  Gly-Gly-Gly-PEG3-TCO		99.53%
  Gly-Gly-Gly-PEG3-TCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-136095

  Tetrazine-biotin
  Tetrazine-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetrazine-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-145066

  Gly-Gly-Gly-PEG4-azide
  Gly-Gly-Gly-PEG4-azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Gly-Gly-Gly-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-400676

  NH2-PEG4-GGFG-CH2-O-CH2-Cbz
  NH2-PEG4-GGFG-CH2-O-CH2-Cbz is a reactant for the synthesis of ADC linker and is used to synthesize Antibody-Drug Conjugates (ADCs)[1].

• HY-116427

  Propargyl-PEG4-thiol
  Propargyl-PEG4-thiol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-thiol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG4-thiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-40144

  Azetidin-3-ol hydrochloride
  Azetidin-3-ol hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azetidin-3-ol hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthes PROTAC.

• HY-130328

  NH-bis-PEG2
  NH-bis-PEG2 is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). NH-bis-PEG2 is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

• HY-151656

  15-Azido-pentadecanoic acid		99.88%
  15-Azido-pentadecanoic acid is a click chemistry reagent containing an azide group. Azido Palmitic Acid can be used to identify and characterize post-translationally palmitylated proteins with using a simple and robust two-step labeling and detection technique[1]. 15-Azido-pentadecanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-126918

  THP-PEG6-OH
  THP-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. THP-PEG6-OH is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

• HY-140306

  Mal-Sulfo-DBCO
  Mal-Sulfo-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Mal-Sulfo-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-W034595

  Eicosanedioic acid
  Eicosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Eicosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis

• HY-151762

  (2R,4S)-Fmoc-D-Pro(4-N3)-OH
  (2R,4S)-Fmoc-D-Pro(4-N3)-OH is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-151652

  Boc-L-Cys(Propargyl)-OH
  Boc-L-Cys(Propargyl)-OH is a click chemistry reagent. Boc-L-Cys(Propargyl)-OH can be used for the research of various biochemical[1][2].

• HY-126671

  Mal-Phe-C4-Val-Cit-PAB
  Mal-Phe-C4-Val-Cit-PAB is a cleavable ADC linker containing a Maleimide group. Mal-Phe-C4-Val-Cit-PAB is used for making antibody-drug conjugate.

• HY-133050

  Hydroxy-PEG6-acid
  Hydroxy-PEG6-acid is a PEG-based non-cleavable ADC linker that can be used in the synthesis of Antibody-Drug Conjugates (ADCs)[1].

• HY-156316A

  SCO-PEG3-NH2 formate
  SCO-PEG3-NH2 formate is a cleavable ADC Linker containing 3 PEG units. SCO-PEG3-NH2 formate can be used as a copper-free click chemical reagent for catalyst-free click reactions[1].

• HY-151828

  N3-Gly-Aeg(Fmoc)-OH
  N3-Gly-Aeg(Fmoc)-OH is a click chemistry reagent containing an azide group. PNA building-block that can be further modified using Click-chemistry[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-W003511

  tans-4-Hydroxy-D-proline hydrochloride
  tans-4-Hydroxy-D-proline hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). tans-4-Hydroxy-D-proline hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PR

• HY-151729

  N3-D-Dab(Boc)-OH
  N3-D-Dab(Boc)-OH is a click chemistry reagent containing an Azide[1]. N3-D-Dab(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-150043A

  MDTF
  MDTF is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130925

  BCN-PEG4-OH
  BCN-PEG4-OH is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. BCN-PEG4-OH is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-W040135

  Fmoc-NH-PEG8-CH2CH2COOH
  Fmoc-NH-PEG8-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130941

  Fmoc-N-bis-PEG3-NH-Boc
  Fmoc-N-bis-PEG3-NH-Boc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-140115

  Bis-(PEG6-acid)-SS
  Bis-(PEG6-acid)-SS is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-43279

  Fmoc-Gly-NH-CH2-O-CH2COOH
  Fmoc-Gly-NH-CH2-O-CH2COOH is an ADC linker. Fmoc-Gly-NH-CH2-O-CH2COOH can be used for synthesis of ADCs[1].

• HY-140147

  Mal-amido-PEG2-Val-Cit-PAB-PNP		98.40%
  Mal-amido-PEG2-Val-Cit-PAB-PNP is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130111

  DMAC-SPP
  DMAC-SPP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-140145

  Mal-PEG4-Val-Cit-PAB-PNP
  Mal-PEG4-Val-Cit-PAB-PNP is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-160795

  Boc-NMeVal-Val-Dil-Dap
  Boc-NMeVal-Val-Dil-Dap is a linker, that can be used for ADC synthesis.

• HY-126523

  N3-C5-NHS ester
  N3-C5-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C5-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-151694

  H-L-Orn(N3)-OH hydrochloride
  H-L-Orn(N3)-OH (hydrochloride) is a click chemistry reagent containing an azide group. H-L-Orn(N3)-OH (hydrochloride) can be used for the research of various biochemical[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-126942

  Amino-PEG6-alcohol
  Amino-PEG6-alcohol is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG6-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-130528

  m-PEG7-MS
  m-PEG7-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG7-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151668A

  Z-L-Aha-OH (DCHA)
  Z-L-Aha-OH (DCHA) is a click chemistry reagent containing azide group[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-151703A

  Boc-D-Lys(N3)-OH (CHA)
  Boc-D-Lys(N3)-OH CHA is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-44234

  Fmoc-Gly-Gly-Phe-OtBu		99.80%
  Fmoc-Gly-Gly-Phe-OtBu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-126885

  DBCO-PEG5-NHS ester
  DBCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1][2]. DBCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-151822

  Hydroxy-PEG3-DBCO
  Hydroxy-PEG3-DBCO is a click chemistry reagent containing an azide group. Hydroxy-PEG3-DBCO is a PEG linker containing a DBCO moiety and a terminal primary hydroxyl group. The hydroxyl can react with a variety of functional groups and the hydrophilic PEG spacer arm can provide better solubility to labeled molecules. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only[1].

• HY-W591402

  3,4-Dibromo-Mal-PEG4-Acid
  3,4-Dibromo-Mal-PEG4-acid is a site specific ADC linker with a dibromomaleimide group and an acid group. The dibromomaleimide group allows for two points of substitution due to the two bromine atoms. The carboxylic acid can react with primary amines in the presence of EDC and HATU to form a stable amide bond. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media.

• HY-130089

  Bis-PEG1-NHS ester
  Bis-PEG1-NHS ester is a nonclaevable 1-unit PEG linker for antibody-agent-conjugation (ADC).

• HY-129359

  PDP-Pfp		98.27%
  PDP-Pfp is a reducible ADC linker used for the agents that target for the extracellular loop 1 (ECL1) of TM4SF1 (transmembrane 4 L6 family member 1)[1].

• HY-151850

  (2S,4R)-Fmoc-L-Pro(4-N3)-OH
  (2S,4R)-Fmoc-L-Pro(4-N3)-OH is a click chemistry reagent containing an azide[1]. (2S,4R)-Fmoc-L-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-111456

  DBCO-NHCO-PEG4-NHS ester
  DBCO-NHCO-PEG4-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-NHCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-151677A

  (2R,4S)-Boc-D-Pro(4-N3)-OH (DCHA)
  (2R,4S)-Boc-D-Pro(4-N3)-OH DCHA is a click chemistry reagent containing an azide[1]. (2R,4S)-Boc-D-Pro(4-N3)-OH (DCHA) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-W419403

  Boc-D-Aza-OH (CHA)
  Boc-D-Aza-OH (CHA) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-W800847

  Mal-Amide-PEG4-Val-Cit-PAB-PNP
  Mal-Amide-PEG4-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151865A

  (2S,4S)-H-L-Pro(4-N3)-OH hydrochloride
  (2S,4S)-H-L-Pro(4-N3)-OH (hydrochloride) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-151819

  N3Ac-OPhOMe		98.21%
  N3Ac-OPhOMe is a click chemistry reagent containing an azide group. N3Ac-OPhOMe can be used for the research of various biochemical[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-136137

  Azide-PEG1-Val-Cit-PABC-OH
  Azide-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azide-PEG1-Val-Cit-PABC-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-151740

  4-Pentynoyl-Val-Ala-PAB-PNP
  4-Pentynoyl-Val-Ala-PAB-PNP is a cleavable ADC linker, that has been used to synthesis cryptophycin conjugates[1]. 4-Pentynoyl-Val-Ala-PAB-PNP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-W352966

  Mal-PEG2-CH2COOH
  Mal-PEG2-CH2COOH is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-76105

  D-Proline, 4-hydroxy-, methyl ester hydrochloride
  D-Proline, 4-hydroxy-, methyl ester hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). D-Proline, 4-hydroxy-, methyl ester hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2

• HY-23641

  NH-bis(C1-Boc)		99.78%
  NH-bis(C1-Boc)is a uncleavable linker used for antibody-drug conjugates (ADC).

• HY-164212

  DBCO-PEG1-OH
  DBCO-PEG2-C2-acid is an ADC Linker. DBCO-PEG2-C2-acid can be used to synthesize Antibody-Drug Conjugates (ADCs)[1].

• HY-130161

  m-PEG4-Br
  m-PEG4-Br is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC) for Trastuzumab (HY-P9907). m-PEG4-Br is placed distally from the monomethyl auristatin E (MMAE) payload to yield an ADC with altered hydrophilicity, antigen binding, and in vitro potency[1]. m-PEG4-Br also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.

• HY-141355

  OPSS-PEG36-acid		98.27%
  OPSS-PEG36-acid is a cleavable 36 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-140148

  Azido-PEG3-Val-Cit-PAB-OH
  Azido-PEG3-Val-Cit-PAB-OH is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG3-Val-Cit-PAB-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-W540023

  endo-BCN-Fmoc-L-Lysine
  Endo-BCN-Fmoc-L-Lysine is a linker containing the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

• HY-41919

  Mal-L-PA-NH-Boc
  Mal-L-PA-NH-Boc is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-133576

  Cyclooctyne-O-amido-PEG4-PFP ester
  Cyclooctyne-O-amido-PEG4-PFP ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Cyclooctyne-O-amido-PEG4-PFP ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-130090

  NHPI-PEG4-C2-Pfp ester
  NHPI-PEG4-C2-Pfp ester is used as a linker for antibody-drug conjugates (ADC).

• HY-130449

  N-Boc-N-bis(PEG4-OH)
  N-Boc-N-bis(PEG4-OH) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-N-bis(PEG4-OH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-133575

  Cyclooctyne-O-amido-PEG3-PFP ester
  Cyclooctyne-O-amido-PEG3-PFP ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Cyclooctyne-O-amido-PEG3-PFP ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-151732

  Z-D-Dbu(N3)-OH
  Z-D-Dbu(N3)-OH is a click chemistry reagent containing an azide group. Z-D-Dbu(N3)-OH can be used for the research of various biochemical[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-44246

  MC-Gly-Gly-Phe-Gly
  MC-Gly-Gly-Phe-Gly is a cleavable ADC linker used for antibody-drug conjugates (ADCs).

• HY-156317

  BCN-endo-PEG7-maleimide
  BCN-endo-PEG7-maleimide is an ADC Linker containing 7 PEG units. BCN-endo-PEG7-maleimide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

• HY-151657

  Spermine(N3BBB)		98.04%
  Spermine(N3BBB) is a click chemistry reagent containing an azide group and can be used for various biochemical studies[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-141150

  Azido-PEG5-Ala-Ala-Asn-PAB
  Azido-PEG5-Ala-Ala-Asn-PAB is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG5-Ala-Ala-Asn-PAB is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-140454

  Azido-PEG8-acid
  Azido-PEG8-acid is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG8-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG8-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-126892

  Bis-PEG7-acid
  Bis-PEG7-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151695

  Fmoc-L-Lys(Pryoc)-OH
  Fmoc-L-Lys(Pryoc)-OH (N2-Fmoc-N6-[(propargyloxy)carbonyl]-L-lysine) is a click chemistry reagent containing an azide group[1].

• HY-141292

  Oleoyl-Gly-Lys-N-(m-PEG11)
  Oleoyl-Gly-Lys-N-(m-PEG11) is a cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-133574

  Mal-amido-PEG3-C1-PFP ester
  Mal-amido-PEG3-C1-PFP ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-147094

  vc-PABC-DM1		99.63%
  vc-PABC-DM1 used to synthesize an ADC molecule based on utilize disulfide linker. vc-PABC-DM1 can be used to explore serum stability[1].

• HY-130103

  Ald-Ph-amido-PEG2-C2-Pfp ester
  Ald-Ph-amido-PEG2-C2-Pfp ester is a nonclaevable 2-unit PEG linker for antibody-agent-conjugation (ADC).

• HY-156494

  Me-Tet-PEG9-COOH
  Me-Tet-PEG9-COOH is an ADC Linker containing 9 PEG units. Me-Tet-PEG9-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

• HY-W052600

  Ethyl azetidine-3-carboxylate hydrochloride
  Ethyl azetidine-3-carboxylate hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Ethyl azetidine-3-carboxylate hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2]

• HY-136052

  Tetrazine-PEG4-oxyamine hydrochloride
  Tetrazine-PEG4-oxyamine (hydrochloride) is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetrazine-PEG4-oxyamine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-W040238

  Fmoc-NH-PEG2-CH2CH2COOH		99.79%
  Fmoc-NH-PEG2-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG2-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-151794

  DACN(Ms) hydrochloride
  DACN(Ms) (hydrochloride) (compound 1ba) is a click chemistry reagent containing cyclononyne alkyne. DCN(Ms) (hydrochloride) has high thermal stability, chemical stability, water solubility, and high reactivity for cycloaddition reactions[1].

• HY-130818

  N-(5-Hydroxypentyl)maleimide		99.89%
  N-(5-Hydroxypentyl)maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as Gemcitabine-O-Si(di-iso)-O-Mc (HY-130812) )[1].

• HY-47968

  SC209 intermediate-1
  SC209 intermediate-1 (Compound A7a) is an ADC linker. SC209 intermediate-1 can be used for synthesis of ADCs[1].

• HY-W035378

  Fmoc-N-methyl-PEG3-CH2CH2COOH
  Fmoc-N-methyl-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-N-methyl-PEG3-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-145676

  Sodium phenyl ethylamido hyaluronate（20% substitution）
  Sodium phenyl ethylamido hyaluronate (20% substitution) is a chemical agent. Sodium phenyl ethylamido hyaluronate (20% substitution) has 20% phenethylamine substitution. The molecular weight is 40-60WD.

• HY-126514

  Propargyl-O-C1-amido-PEG2-C2-NHS ester
  Propargyl-O-C1-amido-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-O-C1-amido-PEG2-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-151684A

  Boc-Ser(O-propargyl)-OH (DCHA)
  Boc-Ser(O-propargyl)-OH (DCHA) is a click chemistry reagent containing a propynyl group.

• HY-129369

  SPDMB
  SPDMB is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs)[1].

• HY-126529

  N3-PEG3-C2-PFP ester
  N3-PEG3-C2-PFP ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-C2-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-130486

  NH2-PEG6-Boc
  NH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. NH2-PEG6-Boc is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

• HY-45672

  Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
  Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate[1].

• HY-W071967

  Alloc-Val-Ala-pAB
  Alloc-Val-Ala-PAB is a peptide cleavable linker used in the synthesis of antibody-drug conjugates (ADCs). The Val-Ala will specifically be cleaved by Cathepsin B. The Alloc group is stable to treatment with piperidine and TFA, but can be easily removed under mild conditions by palladium catalyzed allyl transfer.

• HY-130106

  Ald-Ph-amido-PEG1-C2-NHS ester
  Ald-Ph-amido-PEG1-C2-NHS ester is a nonclaevable 1-unit PEG linker for antibody-agent-conjugation (ADC).

• HY-133547

  NO2-SPP-sulfo
  NO2-SPP-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-140078

  bis-PEG2-endo-BCN		98.10%
  bis-PEG2-endo-BCN is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. bis-PEG2-endo-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-161022S1

  FL118-C3-O-C-amide-C-NH2-d5 formate
  FL118-C3-O-C-amide-C-NH2-d5 formate is a deuterium labeled FL118-C3-O-C-amide-C-NH2 formate. FL118-C3-O-C-amide-C-NH2 formate is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-140105

  Azidoethyl-SS-ethylazide		98.79%
  Azidoethyl-SS-ethylazide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azidoethyl-SS-ethylazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-W025723

  N-Carbobenzoxy-L-homoserine
  N-Carbobenzoxy-L-homoserine (N-(Benzyloxycarbonyl)-L-homoserine) is L-homoserine with N-Carbobenzoxy protecting group, which can be used as a linker (ADC Linker) for the synthesis of Antibody-Drug Conjugates (ADCs).

• HY-148471A

  C3-Amide-C4-NH2
  C3-Amide-C4-NH2 is a potent linker[1].

• HY-129376

  Sulfo-SNPB
  Sulfo-SNPB is a cleavable linker that is used for making antibody-drug conjugate (ADC).

• HY-130112

  N-Succinimidyloxycarbonylpropyl methanethiosulfonate
  N-Succinimidyloxycarbonylpropyl methanethiosulfonate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-114816R

  N-Butanoyl-L-homoserine lactone (Standard)
  N-Butanoyl-L-homoserine lactone (Standard) (C4-HSL (Standard)) is the analytical standard of N-Butanoyl-L-homoserine lactone (HY-114816). This product is intended for research and analytical applications. N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa.

• HY-130182

  Propargyl-PEG8-NH2
  Propargyl-PEG8-NH2 (compound 3b) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-NH2 is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG8-NH2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-129366

  PDB-Pfp
  PDB-Pfp is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-141146

  Mal-amido-PEG8-val-gly-PAB-OH
  Mal-amido-PEG8-val-gly-PAB-OH is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-140014

  Val-Cit		99.38%
  Val-Cit is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151673A

  Poc-Cystamine hydrochloride
  Poc-Cystamine hydrochloride is a click chemistry reagent, a cystamine building block derived from a propynyl group[1].

• HY-133545

  Mal-Ph-CONH-PEG4-​NHS ester
  Mal-Ph-CONH-PEG4- NHS ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-133431

  DBCO-PEG3-SS-NHS ester
  DBCO-PEG3-SS-NHS ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG3-SS-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-141170

  TCO-PEG12-NHS ester
  TCO-PEG12-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG12-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130372

  Propargyl-PEG9-bromide
  Propargyl-PEG9-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG9-bromide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG9-bromide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-133572

  Ald-Ph-amido-PEG11-NH-Boc
  Ald-Ph-amido-PEG11-NH-Boc is a non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-12448

  SPDB		98.82%
  SPDB is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs)[1].

• HY-49206

  CbzNH-PEG8-amide-bis(pentayl-5OBz)
  CbzNH-PEG8-amide-bis(pentayl-5OBz) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-128938

  EC1167
  EC1167 is the linker for EC1169. EC1169 is prostate-specific membrane antigen targeting-tubulysin conjugate. EC1169 has the potential to treat recurrent metastatic, castration-resistant prostate cancer (MCRPC)[1].

• HY-78921AG

  Fmoc-3VVD-OH (GMP)
  Fmoc-3VVD-OH (GMP) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-129361

  Fmoc-Ala-Ala-Asn-PABC-PNP
  Fmoc-Ala-Ala-Asn-PABC-PNP is a peptide cleavable ADC linker[1].

• HY-151782

  H-(Gly)3-Lys(N3)-OH
  The azide function is widely used for coupling to alkyne-containing fragments via the renowned Click reaction. Polyglycine fragments containing up to 7 glycines are reported to bind to surfaces and have potential application in nanotechnology constructs: constructs of Gly7-NHCH2-fragment containing peptides bind on mica surface in aqueous solution[1][2]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-135962

  Boc-Aminooxy-PEG2-bromide
  Boc-Aminooxy-PEG2-bromide is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151691

  Trisulfo-Cy3 Methyltetrazine
  Trisulfo-Cy3 Methyltetrazine is a click chemistry reagent containing an methyltetrazine group. Methyltetrazine-activated Cy3 probe reacts with TCO-containing compounds via an Inverse-Electron-Demand Diels-Alder reaction to form a stable covalent bond and does not require Cu-catalyst or elevated temperatures[1][2].

• HY-141158

  N-(Iodoacetamido)-Doxorubicin
  N-(Iodoacetamido)-Doxorubicin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-138484

  Folate-PEG3-amine		99.69%
  Folate-PEG3-amine is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-156322

  BCN-exo-PEG3-maleimide
  BCN-exo-PEG3-maleimide is an ADC Linker containing 3 PEG units. BCN-exo-PEG3-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which enables the further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.

• HY-136154

  Fmoc-Glu-(Boc)-Val-Cit-PAB-PNP
  Fmoc-Glu-(Boc)-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-140124

  THP-SS-PEG1-Tos
  THP-SS-PEG1-Tos is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-136100

  TCO-PEG1-Val-Cit-PABC-PNP
  TCO-PEG1-Val-Cit-PABC-PNP is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. TCO-PEG1-Val-Cit-PABC-PNP is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

• HY-140116

  Boc-NH-ethyl-SS-propionic acid
  Boc-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-44370

  Boc-Gly-Gly-Gly-Gly-Gly
  (tert-Butoxycarbonyl)glycyl-glycyl-glycyl-glycyl-glycine is a protease cleavable ADC linker with a Boc group on the N terminus, and it is used for the development of antibody-drug conjugates (ADCs). The Boc group can be deprotected under mild acidic conditions to form the free amine.

• HY-136031

  Tetrazine-SS-Biotin
  Tetrazine-SS-Biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetrazine-SS-Biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-135970

  Alkyne-PEG4-SS-PEG4-alkyne
  Alkyne-PEG4-SS-PEG4-alkyne is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Alkyne-PEG4-SS-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-124329

  BS3 Crosslinker
  BS3 Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-145090

  DBCO-N-bis(PEG4-NHS ester)
  DBCO-N-bis(PEG4-NHS ester) is a PEG linker which contains two PEG4-NHS ester and a DBCO group. DBCO-N-bis(PEG4-NHS ester) is useful for protein modification or labeling. DBCO-N-bis(PEG4-NHS ester) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-156813

  Fmoc-Val-Ala-aminomethyl acetate
  Fmoc-Val-Ala-aminomethyl acetate (Compound 58b) is an ADC Linker, and can be used for synthesis of ADCs[1].

• HY-151659

  Fmoc-L-Lys(N3-Gly)-OH
  Fmoc-L-Lys(N3-Gly)-OH is a click chemistry reagent containing a lysine-containing azidoacetyl group building-block for SPPS and can be used for various biochemical studies[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-120845

  Tr-PEG5-OH
  Tr-PEG5-OH is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Tr-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

• HY-120775

  Boc-NH-PEG1-CH2CH2COOH
  Boc-NH-PEG1-CH2CH2COOH is a cleavable (1 unit PEG) ADC linker and also a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of antibody-drug conjugates (ADCs) or PROTACs[1][2].

• HY-129368

  SPDMV
  SPDMV is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs)[1].

• HY-152919

  Mal-amide-PEG8-Val-Cit-PAB-OH
  Mal-amide-PEG8-Val-Cit-PAB-OH is a cleavable ADC linker featuring a maleimide, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB functional group. Maleimide is used to covalently bind free thiols on the cysteine residues of proteins. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery with the help of the PAB structure.

• HY-136108

  Fmoc-Gly3-Val-Cit-PAB-PNP
  Fmoc-Gly3-Val-Cit-PAB-PNP is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130388

  Propargyl-PEG5-NHS ester
  Propargyl-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG5-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-130924

  BCN-PEG3-Biotin
  BCN-PEG3-Biotin is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. BCN-PEG3-Biotin is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-P2376

  Arg-Phe-Asp-Ser
  Arg-Phe-Asp-Ser is a cleavable ADC linker.

• HY-135961

  PTAD-PEG4-amine
  PTAD-PEG4-amine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-148461

  Mal-VC-PAB-PNP
  Mal-VC-PAB-PNP is a cleavable ADC linker. Mal-VC-PAB-PNP can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151685

  Kdo Azide
  Kdo Azide is a click chemistry reagent containing an azide. Kdo Azide is a metabolic labeling reagent[1]. Kdo Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-126521

  N3-C3-NHS ester
  N3-C3-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-130505

  N-Boc-PEG7-alcohol
  N-Boc-PEG7-alcohol is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG7-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-136134

  SS-bis-amino-PEG4-NHS ester
  SS-bis-amino-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-135966

  Azido-PEG3-SS-NHS
  Azido-PEG3-SS-NHS is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG3-SS-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-136086

  Tetrazine-PEG6-amine hydrochloride
  Tetrazine-PEG6-amine (hydrochloride) is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetrazine-PEG6-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-20336G

  Mc-Val-Cit-PABC-PNP (GMP)
  Mc-Val-Cit-PABC-PNP GMP is a GMP grade Mc-Val-Cit-PABC-PNP (HY-20336). Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC linker. Mc-Val-Cit-PABC-PNP can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151733

  Fmoc-D-Dbu(N3)-OH
  Fmoc-D-Dbu(N3)-OH is a click chemistry reagent containing an Azide[1]. Fmoc-D-Dbu(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-130442

  Mal-PEG2-acid
  Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule[1]. Mal-PEG2-acid is also a PROTAC linker that can be used in the synthesis of PROTACs.

• HY-130194

  Azido-PEG5-CH2CO2H
  Azido-PEG5-CH2CO2H is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG5-CH2CO2H is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG5-CH2CO2H is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-W040165

  Amino-PEG3-C2-acid
  Amino-PEG3-C2-acid is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG3-C2-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-130185

  m-PEG7-CH2CH2CHO
  m-PEG7-CH2CH2CHO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG7-CH2CH2CHO is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

• HY-W045598

  Boc-C16-COOH
  Boc-C16-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-C16-COOH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs

• HY-76043

  H-Hyp-OMe hydrochloride
  H-Hyp-OMe hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). H-Hyp-OMe hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]<

• HY-126949

  Aminooxy-PEG3-azide
  Aminooxy-PEG3-azide is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-C2-PEG3-azide is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Aminooxy-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-148211

  Tetrazine-PEG7-amine hydrochloride		99.16%
  Tetrazine-PEG7-amine hydrochloride is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetrazine-PEG7-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-130926

  BCN-PEG3-oxyamine
  BCN-PEG3-oxyamine is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. BCN-PEG3-oxyamine is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-130408

  m-PEG6-Amine
  m-PEG6-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG6-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151681

  (2R,4R)-Fmoc-D-Pro(4-N3)-OH
  (2R,4R)-Fmoc-D-Pro(4-N3)-OH (cis-4-Azido-N-Fmoc-D-proline) is a click chemistry reagent containing an azide group[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-151655

  11-Azidoundecanoic acid		99.35%
  11-Azidoundecanoic acid is a click chemistry reagent containing an azide group. 11-Azidoundecanoic acid acts as a hydrophobic bioconjugation linker that can be further modified at the azido-position using Staudinger ligation or Click-chemistry. 11-Azidoundecanoic acid is substrate of lipoic acid ligase (LpIA) for labeling[1][2]. 11-Azidoundecanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-128890

  DOTA-​NHS-ester
  DOTA-NHS-ester is a linker for affibody molecules and is applied in small animals PET, SPECT, and CT. DOTA-NHS-ester can be used to label radiotherapeutic agents or imaging probes for the detection of tumors[1].

• HY-151842

  Fmoc-EDA-N3
  Fmoc-EDA-N3 is a click chemistry reagent containing an azide group[1]. Fmoc-EDA-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-130324

  Azido-PEG7-amine
  Azido-PEG7-amine is a non-cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG7-amine is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG7-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-140100

  Azidoethyl-SS-propionic acid
  Azidoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azidoethyl-SS-propionic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-130968

  Amino-PEG4-bis-PEG3-propargyl
  Amino-PEG4-bis-PEG3-propargyl is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Amino-PEG4-bis-PEG3-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-141395

  m-PEG4-Boc
  m-PEG4-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. m-PEG4-Boc is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].

• HY-124329A

  BS3 Crosslinker disodium
  BS3 Crosslinker disodium is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130104

  Ald-Ph-amido-PEG2-C2-NHS ester		98.51%
  Ald-Ph-amido-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker for antibody-agent-conjugation (ADC).

• HY-136049

  APN-PEG4-DBCO
  APN-PEG4-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. APN-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-116655

  Hydroxy-PEG1-acid
  Hydroxy-PEG1-acid is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-101159

  Mal-amido-PEG8-C2-acid
  Mal-amido-PEG8-C2-acid (example 142) is a nonclaevable ADC linker[1].

• HY-130937

  DBCO-Val-Cit-PABC-PNP
  DBCO-Val-Cit-PABC-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-Val-Cit-PABC-PNP is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-W800622

  Fmoc-PEG4-Val-Cit-PAB-OH
  Fmoc-PEG4-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The Fmoc protecting group may be removed with piperidine to reveal a primary amine which may be used in coupling reactions to form amides. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.

• HY-130929

  β-Estradiol-6-CMO-PEG3-biotin
  β-Estradiol-6-CMO-PEG3-biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-W090940

  H-Gly-Gly-Phe-OH
  H-Gly-Gly-Phe-OH is a tripeptide linker that may be used in the creation of antibody drug conjugates (ADCs). The N-terminal of the glycine tripeptide is free to perform a variety of reactions such as couplings with carboxylic acids or NHS esters.

• HY-151816

  alpha-Man-TEG-N3
  alpha-Man-TEG-N3 is a click chemistry reagent containing an azide group[1]. alpha-Man-TEG-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-141149

  Fmoc-PEG4-Ala-Ala-Asn-PAB
  Fmoc-PEG4-Ala-Ala-Asn-PAB is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-79369S1

  Succinic anhydride-13C2
  Succinic anhydride-13C2 is the 13C labeled Succinic anhydride[1]. Succinic anhydride is a cyclic anhydride and a nonclaevable ADC linker extracted from patent WO2009064913A1. Succinic anhydride can react with compound 4 of the patent to link the proagent to an amine or hydroxy 1 group of a targeting polypeptide[2].

• HY-151780

  Fmoc-L-Dap(Pentynoyl)-OH
  Fmoc-L-Dap(Pentynoyl)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Dap(Pentynoyl)-OH serves as an amino acid building block for introducing alkyne functions into peptide sequences by standard Fmoc/tBu protocols. The alkyne residue can be engaged for copper catalyzed click reaction with organic azides or with tetrazines for copper-free conjugations[1]. Fmoc-L-Dap(Pentynoyl)-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-41064

  N-Boc-N-methyl-D-Valaldehyde
  N-Boc-N-methyl-D-Valaldehyde is an ADC linker with a BOC protecting group.

• HY-136041

  Boc-amino-PEG3-SSPy
  Boc-amino-PEG3-SSPy is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-W096133

  Biotin-PEG1-azide		99.88%
  Biotin-PEG1-azide is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Biotin-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-140051

  N-Boc-aminoxy-PEG3-propargyl
  N-Boc-aminoxy-PEG3-propargyl is a crosslinker containing a propargyl group and a t-Boc-aminooxy group. N-Boc-aminoxy-PEG3-propargyl can be used in the synthesis of ADC[1].

• HY-W877850

  Mal-C5-N-bis(PEG2-C2-acid)
  Mal-C5-N-bis(PEG2-C2-acid) is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-140226

  m-PEG10-amine
  m-PEG10-amine is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. m-PEG10-amine is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-130457

  m-PEG4-MS
  m-PEG4-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG4-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-W040132

  Boc-NH-PEG4-CH2CH2COOH
  Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1]. Boc-NH-PEG4-CH2CH2COOH is also a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC)[2].

• HY-136088

  Acid-PEG1-bis-PEG3-BCN
  Acid-PEG1-bis-PEG3-BCN is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Acid-PEG1-bis-PEG3-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-133546

  Ald-Ph-amido-PEG11-C2-NH2
  Ald-Ph-amido-PEG11-C2-NH2 is a non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-43869

  Vipivotide tetraxetan Ligand-Linker Conjugate
  Vipivotide tetraxetan Ligand-Linker Conjugate (PSMA-617 Ligand-Linker Conjugate) is a complex composed of pharmacophore group Glutamate-urea-Lysine peptide coupling linker, which can be used to synthesize Vipivotide tetraxetan (PSMA-617). Glutamate-urea-Lysine selectively binds to prostate-specific membrane antigen (PSMA)[1].

• HY-160182

  INX-P
  INX-P is glucocorticosteroid-target antibody drug conjugate (ADC)[1].

• HY-W426106

  Gly-NH-CH2-Boc
  Gly-NH-CH2-Boc is a cleavable ADC linker that can be used to synthesize antibody-conjugated active molecules (ADC)[1].

• HY-148031

  MC-Ala-Ala-Asn-PAB-PNP
  MC-Ala-Ala-Asn-PAB-PNP is a peptide, can be used to synthesize specifically activated micromolecular target coupling body[1].

• HY-151827

  DBCO-PEG2-NHS ester
  DBCO-PEG2-NHS ester is a click chemistry reagent containing an azide group. DBCO-PEG2-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only[1].

• HY-156301A

  Me-Tet-PEG8-NH2 hydrochloride
  Me-Tet-PEG8-NH2 (hydrochloride) is an ADC Linker containing 2 PEG units. Me-Tet-PEG8-NH2 (hydrochloride) can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

• HY-141143

  MC(C5)-Val-Cit
  MC(C5)-Val-Cit is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-78932A

  Dap-NE hydrochloride		99.99%
  Dap-NE hydrochloride is a dipeptide hydrochloride and a cleavable ADC Linker.Dap-NE hydrochloride can be used to connect Antibody and toxin molecules (Cytotoxin) to synthesize Antibody-Drug Conjugates (ADCs)[1].

• HY-151666

  6-Azido-D-lysine
  6-Azido-D-lysine is a click chemistry reagent containing an azide[1]. 6-Azido-D-lysine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-136034

  Azido-PEG1-Val-Cit-OH
  Azido-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG1-Val-Cit-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-126505

  Mal-​PEG4-​NHS ester
  Mal-PEG4-NHS ester is a non-cleavable ADC linker which links Quantum dots (QDs) with PEGylated liposomes[1].

• HY-126495A

  Sulfo-LC-SPDP sodium
  Sulfo-LC-SPDP sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-W018174

  m-PEG3-Amine
  m-PEG3-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG3-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-129351

  Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP
  Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-133412

  DBCO-NHCO-S-S-NHS ester
  DBCO-NHCO-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-NHCO-S-S-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-120237

  m-PEG7-Amine
  m-PEG7-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG7-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130935

  DBCO-Val-Cit-OH
  DBCO-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-Val-Cit-OH is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-138327

  1,6-Bis(mesyloxy)hexane
  16-Bismesyloxyhexane is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-W421970

  Tup hydrochloride
  Tup hydrochloride is a cleavable ADC linker.

• HY-151639

  (2S,4R)-H-L-Pro(4-N3)-OH
  (2S,4R)-H-L-Pro(4-N3)-OH is a click chemistry reagent containing an azide group. (2S,4R)-H-L-Pro(4-N3)-OH can be used for the research of various biochemical studies[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-130961

  Boc-Val-Dil-Dap-OH		98.52%
  Boc-Val-Dil-Dap-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-W010975

  Fmoc-Lys-OH hydrochloride
  Fmoc-Lys-OH hydrochloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Lys-OH hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

• HY-33615

  Methyl azetidine-3-carboxylate hydrochloride
  Methyl azetidine-3-carboxylate hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyl azetidine-3-carboxylate hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs<

• HY-130936

  DBCO-Val-Cit-PABC-OH
  DBCO-Val-Cit-PABC-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-Val-Cit-PABC-OH is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-W096135

  Biotin-PEG1-NH2
  Biotin-PEG1-NH2 is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-145488

  MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D		99.65%
  MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151790

  Alkyne-SS-COOH
  Alkyne-SS-COOH is a click chemistry reagent containing an alkyne group. Alkyne-SS-COOH can be used for the research of various biochemical[1].

• HY-139245

  MC-Ala-Ala-Asn-PAB
  MC-Ala-Ala-Asn-PAB is a linker extracted from patent CN104147612A, page 14. MC-Ala-Ala-Asn-PAB can be used to synthesis the tumor microenvironment specific activated micromolecular targeted conjugate[1].

• HY-141145

  OPSS-Val-Cit-PAB-PNP
  OPSS-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-21577

  Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine
  Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane is also a PEG/Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-151847

  N3-TEMPO
  N3-TEMPO is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-135974

  Amino-PEG3-SS-acid
  Amino-PEG3-SS-acid is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-133548

  NO2-SPDB-sulfo
  NO2-SPDB-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-44222

  MAC glucuronide linker-2		99.38%
  MAC glucuronide linker-2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-125305

  Z-AEVD-FMK
  Z-AEVD-FMK is a cleavable ADC linker for the synthesis of antibody active molecule conjugates (ADCs).

• HY-133581

  Mal-PEG3-C1-NHS ester
  Mal-PEG3-C1-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-140146

  Mal-amido-PEG2-Val-Cit-PAB-OH
  Mal-amido-PEG2-Val-Cit-PAB-OH is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-101153

  MC-Val-Ala-OH
  MC-Val-Ala-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130973

  Mal-PEG4-bis-PEG4-propargyl		99.05%
  Mal-PEG4-bis-PEG4-propargyl is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Mal-PEG4-bis-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-148463

  MP-Ala-Ala-PAB		98.76%
  MP-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-W040168

  Amino-PEG2-C2-acid
  Amino-PEG2-C2-acid is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG2-C2-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-136157

  Py-ds-dmBut-amido-PEG4-NHS ester
  Py-ds-dmBut-amido-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-138651

  PAB-Val-Lys-Boc
  PAB-Val-Lys-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) for stimulating an immune response[1].

• HY-151778

  Fmoc-Abg(N3)-OH
  Fmoc-Abg(N3)-OH is a click chemistry reagent containing an azide group. Fmoc-Abg(N3)-OH has the potential to synthesize peptide nucleic acids (PNA) and peptoids. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-48321

  N-Cbz-glycyl-glycyl-D-phenylalanine
  N-Cbz-glycyl-glycyl-D-phenylalanine is a cleavable ADC linker.

• HY-128925

  AMAS
  AMAS is a nonclaevable heterobifunctional crosslinker with NHS ester and maleimide groups that allows covalent conjugation of amine- and sulfhydryl-containing molecules.

• HY-126510

  MC-PEG2-C2-​NHS ester
  MC-PEG2-C2- NHS ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-151721

  H-D-Orn(N3)-OH hydrochloride
  H-D-Orn(N3)-OH hydrochloride is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-136135

  (2-pyridyldithio)-PEG1-hydrazine		99.30%
  (2-pyridyldithio)-PEG1-hydrazine is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-168550

  STI-8811 drug-linker
  STI-8811 drug-linker is a linker for synthesis of ADC molecule STI-8811[1].

• HY-131086

  Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2		98.58%
  Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-151664

  H-alpha-Prg-D-Ala-OH
  H-alpha-Prg-D-Ala-OH is a click chemistry reagent containing an azide group[1].

• HY-78921

  Fmoc-3VVD-OH		99.99%
  Fmoc-3VVD-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151791

  (S,R,S)-AHPC-C6-PEG3-butyl-N3
  (S,R,S)-AHPC-C6-PEG3-butyl-N3 is a click chemistry reagent containing an azide group. (S,R,S)-AHPC-C6-PEG3-butyl-N3 serves as crosslinker-E3 ligase ligand conjugate, Click reactive protein degrader building block for PROTAC research, Template for synthesis of targeted protein degrader, VH032 conjugate[1]. (S,R,S)-AHPC-C6-PEG3-butyl-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-W800814

  Azido-PEG8-Amido-Val-Cit-PAB
  Azido-PEG8-Amido-Val-Cit-PAB is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. Azido will react with DBCO, BCN or other alkyne groups through click chemistry. PEG spacer increases aqueous solubility. Reagent grade, for research purpose.

• HY-147093

  vc-PAB-DMEA-PNU159682
  vc-PAB-DMEA-PNU159682 (compound I.47) can be used to synthesize the ADC molecule based on Sulfomaleimide-based Linker. vc-PAB-DMEA-PNU159682 has good serum stability[1].

• HY-126951

  Aminooxy-PEG2-alcohol
  Aminooxy-PEG2-alcohol is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-PEG2-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].

• HY-164296

  SMP-96745
  SMP-96745 is a dual-drug targeting linker-drug conjugate and can be used for study of cancer[1].

• HY-100138

  2-Aminoethyl-mono-amide-DOTA-tris(tBu ester)
  2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) is a metal chelator precursor containing a DOTA macrocyclic structure. DOTA can form highly stable complexes with metal ions (such as 68Ga, 177Lu) through four nitrogen atoms and four carboxylic acid groups to mediate targeted delivery of radionuclides. The tert-butyl ester group (tBu ester) of 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) also protects the carboxylic acid group during synthesis, and forms a free carboxyl group after deprotection reaction for coupling with targeting molecules (such as antibodies, peptides). 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) may be combined with tumor pre-targeting systems through bioorthogonal reactions (such as reverse electron demand Diels-Alder reaction) to study radioactive imaging or therapy of tumor tissues, and is mainly used in tumor pre-targeting research in the field of nuclear medicine[1][2].

• HY-129375

  SNPB-sulfo-Me
  SNPB-sulfo-Me is a cleavable linker that is used for making antibody-drug conjugate (ADC).

• HY-133426

  Ald-Ph-amido-PEG4-propargyl
  Ald-Ph-amido-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Ald-Ph-amido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-126364

  Mc-​Val-​Ala-​PAB
  Mc- Val- Ala- PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-151665

  Alkyne-PEG2-iodide
  Alkyne-PEG2-iodide is a click chemistry reagent with terminal alkyne and alkyl iodide groups.

• HY-W034599

  Boc-C14-COOH
  Boc-C14-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-C14-COOH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

• HY-W040246

  Fmoc-NH-PEG6-CH2CH2COOH		99.29%
  Fmoc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-140130

  PC Biotin-PEG3-alkyne
  PC Biotin-PEG3-alkyne is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. PC Biotin-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-101151

  sulfo-SPDB
  sulfo-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-140081

  Boc-gly-PEG3-endo-BCN
  Boc-gly-PEG3-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-gly-PEG3-endo-BCN is also a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. Boc-gly-PEG3-endo-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-133544

  Mal-CO-PEG5-​NHS ester
  Mal-CO-PEG5- NHS ester is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-151687

  Fmoc-L-Tyr(2-azidoethyl)-OH
  Fmoc-L-Tyr(2-azidoethyl)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Tyr(2-azidoethyl)-OH is unnatural Fmoc-protected Tyrosine derivative bears an azidoethyl substitution as reactive handle e.g. for biorthogonal conjugations, via a Cu(I)-catalyzed 1,3-dipolar Click cycloaddition with alkynes. And azido-UAAs can be employed as IR reporters[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-19318

  Fmoc-Val-Cit-PAB		99.39%
  Fmoc-Val-Cit-PAB is a cleavable antibody-conjugated active molecule (ADC) commonly used linker.

• HY-130099

  Ald-Ph-amido-PEG2
  Ald-Ph-amido-PEG2 is a noncleavable ADC linker for antibody-drug conjugate[1].

• HY-W017755

  (R)-Azetidine-2-carboxylic acid
  (R)-Azetidine-2-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). (R)-Azetidine-2-carboxylic acid is also a alkyl chain-based PROTAC linker that can be

• HY-12362G

  Val-cit-PAB-OH (GMP)
  Val-cit-PAB-OH GMP is a GMP grade Val-cit-PAB-OH (HY-12362). Val-cit-PAB-OH is a degradable ADC linker.

• HY-126511

  Propargyl-C1-NHS ester
  Propargyl-C1-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC). Propargyl-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-140123

  THP-SS-PEG1-Boc
  THP-SS-PEG1-Boc is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130387

  Propargyl-PEG4-Tos
  Propargyl-PEG4-Tos is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-Tos is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1][2]. Propargyl-PEG4-Tos is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-140113

  Acid-PEG3-SS-PEG3-acid
  Acid-PEG3-SS-PEG3-acid is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130346

  DBCO-PEG4-DBCO
  DBCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-151814

  (2S,4S)-Fmoc-L-Pro(4-NHPoc)-OH
  (2S,4S)-Fmoc-L-Pro(4-NHPoc)-OH is a click chemistry reagent containing an azide group.

• HY-45672G

  Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (GMP)
  Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-45672). Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate[1].

• HY-W007324

  Maleimide
  Maleimide can be used for production of antibody-drug conjugate (ADC) which is used in cancer research. Maleimide also be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes[1][2].

• HY-130927

  BCN-PEG4-Ts
  BCN-PEG4-Ts is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. BCN-PEG4-Ts is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-140244

  Gly-PEG3-amine
  Gly-PEG3-amine is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-W540192

  SCO-PEG2-Maleimide
  SCO-PEG2-Maleimide is an ADC Linker containing 3 PEG units. SCO-PEG2-Maleimide can be used as a copper-free click chemical reagent for catalyst-free click reactions. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.

• HY-130976

  N-Boc-Val-Dil-Dap-Doe
  N-Boc-Val-Dil-Dap-Doe is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-40151

  Methyl 1-Boc-azetidine-3-carboxylate
  Methyl 1-Boc-azetidine-3-carboxylate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyl 1-Boc-azetidine-3-carboxylate is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1

• HY-111895A

  Macropa-NH2 hydrochloride		99.39%
  Macropa-NH2 hydrochloride is the precursor of Macropa-NCS. Macropa-NCS is conjugated to Anti-Human HER2 (HY-P9907) as well as to the prostate-specific membrane antigen-targeting compound RPS-070 and is a promising therapeutic radionuclide applied in the treatment of soft-tissue metastases[1].

• HY-44235

  MC-Gly-Gly-Phe
  MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).

• HY-131955

  Fmoc-aminooxy-PEG2-NH2
  Fmoc-aminooxy-PEG2-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130966

  TCO-PEG1-Val-Cit-PABC-OH
  TCO-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. TCO-PEG1-Val-Cit-PABC-OH is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

• HY-151844

  2-Azido-adenosine
  2-Azido-adenosine is a click chemistry reagent containing an azide group[1]. 2-Azido-adenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-130085

  Mal-PEG6-NHS ester
  Mal-PEG6-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 6-unit PEG and a NHS ester.

• HY-135973

  BCN-SS-NHS
  BCN-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. BCN-SS-NHS is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-W006629

  (4S)​-4-Hydroxy-D-proline methyl ester hydrochloride
  (4S)-4-Hydroxy-D-proline methyl ester hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). (4S)-4-Hydroxy-D-proline methyl ester hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

• HY-W071584

  N-Boc-PEG6-alcohol
  N-Boc-PEG6-alcohol is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG6-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-156507

  DBCO-PEG3-NHS ester		98.47%
  DBCO-PEG3-NHS ester (cpmpd 45) is a ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-164273

  Azidoacetyl-Val-Cit-PAB-OH
  Azidoacetyl-Val-Cit-PAB-OH is a cleavable ADC linker.

• HY-44980G

  Fmoc-Gly-NH-CH2-acetyloxy (GMP)
  Fmoc-Gly-NH-CH2-acetyloxy GMP is a GMP grade Fmoc-Gly-NH-CH2-acetyloxy (HY-44980). Fmoc-Gly-NH-CH2-acetyloxy is a cleavable linker that can be used to synthesize antiboy-drug Conjugates (ADCs).

• HY-151862

  3-Azidopropylamine		99.57%
  3-Azidopropylamine is a click chemistry reagent containing an azide group. 3-Azidopropylamine can react with the starch sugar of potato starch for complexation and transfection of plasmid DNA[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-151702A

  (2S)-N3-IsoSer (DCHA)		98.29%
  (2S)-N3-IsoSer DCHA is a click chemistry reagent, a chiral alpha-hydroxypropinoic acid, containing azide group[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-117009

  Bis-PEG9-NHS ester
  Bis-PEG9-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG9-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151866A

  (S)-N3-HABA (DCHA)
  (S)-N3-HABA (DCHA) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-42640

  Boc-NH-PEG4-CH2COOH
  Boc-NH-PEG4-CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC). Boc-NH-PEG4-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-148462

  Fmoc-Ala-Ala-PAB		98.86%
  Fmoc-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-78932G

  Dap-NE hydrochloride (GMP)
  Dap-NE hydrochloride (GMP) is Dap-NE hydrochloride (HY-78932A) produced by using GMP guidelines. Dap-NE hydrochloride is an intermediate used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130144

  Ald-CH2-PEG3-azide
  Ald-CH2-PEG3-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Ald-CH2-PEG3-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Ald-CH2-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-134734

  BCN-exo-PEG7-maleimide
  BCN-exo-PEG7-maleimide is an ADC Linker containing 7 PEG units. BCN-exo-PEG7-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.

• HY-164209

  DBCO-PEG3-C1-acid	Chemical
  DBCO-PEG3-C1-acid is an antibody–drug conjugate (ADC) linker, which is used as a reaction handle for strain-promoted azide-alkyne click reaction[1].

• HY-130932

  Boc-Val-Ala-PAB-PNP
  Boc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-40152

  1-Boc-azetidine-3-yl-methanol
  1-Boc-azetidine-3-yl-methanol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Boc-azetidine-3-yl-methanol is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]

• HY-126503

  trans-Sulfo-SMCC
  trans-Sulfo-SMCC is a non-cleavable and membrane permeable ADC crosslinker.

• HY-151796

  DACN(Ms,Ns)
  DACN(Ms,Ns) is a click chemistry reagent containing a cyclic alkyne group[1].

• HY-133466

  Methyltetrazine-PEG4-SS-NHS ester
  Methyltetrazine-PEG4-SS-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Methyltetrazine-PEG4-SS-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-130967

  Ald-Ph-PEG4-bis-PEG4-propargyl
  Ald-Ph-PEG4-bis-PEG4-propargyl is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Ald-Ph-PEG4-bis-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-157275

  Gly-Gly-Gly-PEG2-azide
  Gly-Gly-Gly-PEG2-azide is an ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130097

  Ald-Ph-amido-PEG4-C2-acid		99.09%
  Ald-Ph-amido-PEG4-C2-acid is a noncleavable linker used for the antibody-drug conjugate (ADC).

• HY-49463

  Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Gly-CH2-O-CH2-Cbz
  Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Gly-CH2-O-CH2-Cbz is an ADC linker that can be used in the synthesis of ADCs (such as Trastuzumab deruxtecan and U3-1402).

• HY-133540G

  Maleimide-DOTA (GMP)
  Maleimide-DOTA (Maleimido-mono-amide-DOTA) (GMP) is Maleimide-DOTA (HY-133540) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151831

  Me-PMeOx(100)-N3 (MW 8.5kDa)
  Me-PMeOx(100)-N3 (MW 8.5kDa) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-151764A

  N3-D-Orn(Boc)-OH (CHA)
  N3-D-Orn(Boc)-OH (CHA) is a Boc-protected pentanoic amino acid derivative, can be used as a click chemistry reagent and has been used to synthesis antibody-drug conjugates (ADC)[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-161022

  FL118-C3-O-C-amide-C-NH2
  FL118-C3-O-C-amide-C-NH2 (compound 6a) is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151772

  Methyltetrazine-PEG12-t-butyl ester
  Methyltetrazine-PEG12-t-butyl ester is a monodisperse PEG compound. Methyltetrazine-PEG12-t-butyl ester is a click chemistry reagent containing a tetrazine group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1].

• HY-129373

  SPDMV-sulfo
  SPDMV-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs).

• HY-139859

  APN-PEG36-tetrazine
  APN-PEG36-tetrazine is an analogue of APN-PEG4-tetrazine. APN-PEG4-tetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. APN-PEG36-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-65039

  Boc-Hyp-OMe
  Boc-Hyp-OMe is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-Hyp-OMe is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2].

• HY-136132

  MC-VC-PAB-NH2
  MC-VC-PAB-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-136046

  PTAD-PEG4-alkyne		99.26%
  PTAD-PEG4-alkyne is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. PTAD-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-151815

  beta-Lac-TEG-N3
  beta-Lac-TEG-N3 is a click chemistry reagent containing an azide group. beta-Lac-TEG-N3 can be used for the research of various biochemical[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-141161B

  (R,E)-TCO-PEG8-acid
  (R)-TCO-PEG8-acid is an ADC linker containing 8 PEG units. (R)-TCO-PEG8-acid can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.

• HY-126530

  PPC-NB		99.90%
  PPC-NB is a glutathione cleavable linker used for the antibody-drug conjugate (ADC)[1].

• HY-128970

  Mp-polymer ester
  Mp-polymer ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-140108

  Propargyl-PEG1-SS-alcohol
  Propargyl-PEG1-SS-alcohol is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG1-SS-alcohol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-W007713

  Fmoc-8-amino-3,6-dioxaoctanoic acid
  Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-8-amino-3,6-dioxaoctanoic acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-136032

  Tetrazine-SS-NHS
  Tetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetrazine-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-W250541

  Fmoc-Gly-NH-CH2-O-Cyclopropane-CH2COOH
  Fmoc-Gly-NH-CH2-O-Cyclopropane-CH2COOH is an intermediate in the synthesis of ADC linker.The linker composed of Benzyl 2-cyclopropyl-2-hydroxyacetate can be coupled to Exatecan (HY-13631) and combined with antibodies (such as antibody hu2F7)[1].

• HY-151709A

  N3-L-Cit-OH (DCHA)
  N3-L-Cit-OH DCHA is a click chemistry reagent containing an azide group. N3-L-Cit-OH DCHA can be used to construct peptidomimetic ADC linkers using Click-chemistry[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-130940

  PTDA-PEG4-azide		99.34%
  PTAD-PEG4-N3 is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. PTAD-PEG4-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-151769

  TCO-PEG2-Sulfo-NHS ester-EDC Urea
  TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent containing an azide group. TCO-PEG2-Sulfo-NHS ester is a PEG linker containing a TCO moiety and a sulfo-NHS ester moiety. The sulfo group makes this molecule soluble in waqueous buffer. This reagent can be used to label antibodies, proteins and other primary amine-containing macromolecules with TCO moiety. Reagent grade, for research use only[1]. TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

• HY-W019799

  Amino-PEG8-Boc
  Amino-PEG8-Boc is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG8-Boc is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-151746

  N3-Gly-Gly-Gly-OH
  N3-Gly-Gly-Gly-OH is a oligo-Gly click chemistry reagent containing an azide group. Oligo-Gly also has been used as linker to combine different subunits of dimeric or oligomeric proteins or to create artificial multi-domain proteins. By modification into Gly-Gly-Gly-Ser motifs high solubility can be achieved[1][2][3]. N3-Gly-Gly-Gly-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-W800625

  Boc-PEG4-Val-Cit-PAB-OH
  Boc-PEG4-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The Boc protecting group may be removed with acid to reveal a primary amine which may be used in coupling reactions to form amides. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.

• HY-151670

  Biotin-PEG(4)-SS-Azide
  Biotin-PEG(4)-SS-Azide is a click chemistry reagent containing an azide group. Biotin-PEG(4)-SS-Azide can be used for the research of various biochemical[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-160790

  β-Glu-PNP
  β-Glu-PNP is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-145489

  Mal-PEG2-Val-Cit-PABA
  Mal-PEG2-Val-Cit-PABA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-116270

  DBCO-Maleimide
  DBCO-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-140144

  Mal-PEG1-Val-Cit-PAB-PNP		98.41%
  Mal-PEG1-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151718A

  Boc-L-Tyr(PEG(3)-N3)-OH (DCHA)
  Boc-L-Tyr(PEG(3)-N3)-OH DCHA is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-W067509

  m-PEG3-CH2CH2COOH
  m-PEG3-CH2CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG3-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

• HY-141218

  m-PEG10-alcohol
  m-PEG10-alcohol (Decaethylene glycol monomethyl ether) is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. m-PEG10-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-130653

  Azido-PEG4-C2-acid
  Azido-PEG4-C2-acid a PEG-based PROTAC linker can be used in the synthesis of vRucaparib-TP4. Azido-PEG4-C2-acid is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG4-C2-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-49929

  MC-GGFG-NH-CH2-O-CH2-cyclopropane-COOH
  MC-GGFG-NH-CH2-O-CH2-cyclopropane-COOH is an ADC linker that can be combined with the cytotoxic Camptothecin (HY-16560) to form ADC-related drug-linker conjugates (Drug-Linker Conjugates for ADC ).MC-GGFG-NH-CH2-O-CH2-cyclopropane-COOH is conjugated to Camptothecin, which can further bind to the antibody Trastuzumab (HY-P9907) to form Antibody-Drug Conjugates (ADCs)[1].

• HY-130102

  Ald-Ph-amido-PEG3-C2-Pfp ester
  Ald-Ph-amido-PEG3-C2-Pfp ester is an noncleavable ADC linker, which belongs to a polyethylene glycol (PEG) linker.

• HY-42149

  NH2-PEG2-C2-Boc
  NH2-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. NH2-PEG2-C2-Boc is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

• HY-151722

  Boc-D-Orn(N3)-OH (CHA)
  Boc-D-Orn(N3)-OH (CHA) is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-130091

  NHPI-PEG4-C2-NHS ester		98.88%
  NHPI-PEG4-C2-NHS ester is an ADC Linker, which can be used to synthesize antibody-drug conjugates (ADCs)[1].

• HY-156315A

  SCO-PEG2-NH2 formate
  SCO-PEG2-NH2 formate is a cleavable ADC Linker containing 2 PEG units. SCO-PEG2-NH2 formate can be used as a copper-free click chemical reagent for catalyst-free click reactions.

• HY-151663

  Fmoc-Abu(3-N3) (2R,3R)
  Fmoc-Abu(3-N3) (Fmoc-Abu(3-N3)-OH) (2R,3R) is a click chemistry reagent containing an azide group. Fmoc-Abu(3-N3) (2R,3R) can be used for the research of various biochemical[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-41049

  NSC 135130
  NSC 135130 (compound 11a) is a BOC-protected ADC linker that can be linked to tubulin-targeting inhibitors.Can be used to synthesize drug conjugates[1].

• HY-126975

  Propargyl-PEG3-acid
  Propargyl-PEG3-acid is a non-cleavable (3 unit PEG) ADC linker and also a PEG-based PROTAC linker that can be used to synthesis 6-OHDA-PEG3-yne. 6-OHDA-PEG3-yne contains 6-OHDA (HY-B1081, HY-B1081A) and Propargyl-PEG3-acid[1]. Propargyl-PEG3-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-140242

  NH2-PEG4-Lys(Boc)-NH-(m-PEG24)
  NH2-PEG4-Lys(Boc)-NH-(m-PEG24) is a cleavable 28 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-140138

  PC SPDP-NHS carbonate ester
  PC SPDP-NHS carbonate ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-132252

  Mal-PEG8-Val-Ala-PABC		99.06%
  Mal-PEG8-Val-Ala-PABC is a cleavable Tesirine linker used in the synthesis of Tesirine, a agent-linker conjugate for ADC[1].

• HY-W591438

  Mc-Phe-Lys(Boc)-PAB		99.41%
  Mc-Phe-Lys(Boc)-PAB is an ADC linker[1].

• HY-W097109A

  Fmoc-(D-Phe)-OSu
  Fmoc-(D-Phe)-Osu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-48692

  Mal-EGGGG-PEG8-amide-bis(deoxyglucitol)		99.89%
  Mal-EGGGG-PEG8-amide-bis(deoxyglucitol) is a cleavable ADC linker.

• HY-151697

  DACN(Tos2)
  DACN(Tos2) is a a click chemistry reagent containing an cycloalkynes group. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. DACN(Tos2) through such strain-promoted azide-alkyne cycloadditions (SPAAC) using cycloalkynes. DACN(Tos2) can be used for the research of molecular conjugation[1].

• HY-130108

  N3-PEG4-C2-Pfp ester
  N3-PEG4-C2-Pfp ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG4-C2-Pfp ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-136084

  Mal-PEG4-(PEG3-DBCO)-(PEG3-TCO)
  Mal-PEG4-(PEG3-DBCO)-(PEG3-TCO) is a cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Mal-PEG4-(PEG3-DBCO)-(PEG3-TCO) is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

• HY-136106

  Fmoc-Gly3-Val-Cit-PAB
  Fmoc-Gly3-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-141382

  Bromoacetamido-PEG4-acid
  Bromoacetamido-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromoacetamido-PEG4-acid is also a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

• HY-41189

  Fmoc-Val-Cit-PAB-PNP
  Fmoc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Val-Cit-PAB-PNP has superior plasma stability comparable to that of non-cleavable linkers[1][2][3].

• HY-133062

  Fmoc-NH-PEG5-CH2COOH
  Fmoc-NH-PEG5-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG5-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-W591373

  DBCO-PEG4-Val-Ala-PAB
  DBCO-PEG4-Val-Ala-PAB is a cleavable ADC linker. The Val-Ala linkers can be cleaved by Cathepsin B. The DBCO groups is commonly used for Click Chemistry reactions. PEG spacer improves the compound's aqueous solubility.

• HY-151668

  Z-L-Aha-OH
  Z-L-Aha-OH is a click chemistry reagent containing azide group[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-W040289

  Mal-amido-PEG2-NHS ester		99.32%
  Mal-amido-PEG2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2].

• HY-128930

  6-O-2-Propyn-1-yl-D-galactose
  6-O-2-Propyn-1-yl-D-galactose is a nonclaevable glycolinker for the functionalization of cytotoxic agents and applications in antibody-agent conjugation. 6-O-2-Propyn-1-yl-D-galactose is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-140004

  Azide-PEG3-Tos
  Azide-PEG3-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azide-PEG3-Tos is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. Azide-PEG3-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-136155

  Fmoc-NH-Azide-PEG4-L-Lysine-PFP ester
  Fmoc-NH-Azide-PEG4-L-Lysine-PFP ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Fmoc-NH-Azide-PEG4-L-Lysine-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-136098

  DBCO-PEG4-acetic-Val-Cit-PAB		98.21%
  DBCO-PEG4-acetic-Val-Cit-PAB is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG4-acetic-Val-Cit-PAB is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-164732

  Fmoc-Lys(DOTA)-OH
  Fmoc-Lys(DOTA)-OH is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-19318A

  Fmoc-Val-D-Cit-PAB
  Fmoc-D-Val-Cit-PAB is a cleavable linker for antibody-agent-conjugation (ADC)[1].

• HY-151734

  (2R,3S)-Fmoc-Abu(3-N3)-OH
  (2R,3S)-Fmoc-Abu(3-N3)-OH is a click chemistry reagent containing an azide group[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-113931

  Aminooxy-PEG2-azide
  Aminooxy-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Aminooxy-PEG2-azide is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. Aminooxy-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-130922

  BCN-PEG1-Val-Cit-OH
  BCN-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. BCN-PEG1-Val-Cit-OH is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-136547

  Boc-Val-Ala-PAB		98.36%
  Boc-Val-Ala-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate (ADCs)[1][2].

• HY-130974

  Ald-Ph-PEG4-bis-PEG3-methyltetrazine
  Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-136054

  N3-PEG5-aldehyde
  N3-PEG5-aldehyde is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. N3-PEG5-aldehyde is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-140143

  Mal-PEG4-Val-Cit-PAB-OH
  Mal-PEG4-Val-Cit-PAB-OH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130100

  Ald-Ph-amido-PEG3-C1-Boc
  Ald-Ph-amido-PEG3-C1-Boc is an ADC linker, which belongs to a polyethylene glycol (PEG) linker.

• HY-129350

  Fmoc-Phe-Lys(Trt)-PAB-PNP
  Fmoc-Phe-Lys(Trt)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-150230

  Desthiobiotin-Iodoacetamide
  Desthiobiotin-Iodoacetamide can be used as an ADC Linker. Desthiobiotin-Iodoacetamide also acts as a probe used to label the the Oridonin (HY-N0004)-treated cell lysis[1].

• HY-148464

  MC-Ala-Ala-PAB
  MC-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151636

  10-Undecynoyl-OSu
  10-Undecynoyl-OSu is a click chemistry reagent. 10-Undecynoyl-OSu is used as a hydrophobic bioconjugation linker that can be further modified at the alkyne using Click-chemistry[1].

• HY-147084

  KY371		98.20%
  KY371 is a click chemistry reagent containing an alkyne group. KY371 is a broad-range glycosidase inhibitor. KY371 can combine with proteomic analysis of targeted protein to study glycosidases[1].

• HY-133439

  BCN-PEG4-NHS ester
  BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. BCN-PEG4-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-140096

  Aminoethyl-SS-propionic acid
  Aminoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151661

  N3-L-Val-OH (CHA)		99.15%
  N3-L-Val-OH (CHA) is a click chemistry containing an azide group, a valine derivative. N3-L-Val-OH (CHA) can also be used as a synthetic intermediate for Valaciclovir (Valacyclovir)[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-140097

  Amino-SS-PEG12-acid
  Amino-SS-PEG12-acid is a cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151858

  Boc-L-Lys(N3)-OH
  Boc-L-Lys(N3)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-108368A

  Azido-PEG2-CH2COOH (CHA)
  Azido-PEG2-CH2COOH (CHA) is a azido-modified PEG2 acid, can be used as a click chemistry reagent[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-126522

  N3-C4-NHS ester		99.34%
  N3-C4-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-151745

  N3-TOTA-Suc
  N3-TOTA-Suc is a click chemistry reagent containing an azide group. Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompatible, rapid and highly specific in biological environments[1]. N3-TOTA-Suc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-133540

  Maleimide-DOTA
  Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-136035

  Methyltetrazine-SS-PEG4-Biotin
  Methyltetrazine-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Methyltetrazine-SS-PEG4-Biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-151709

  N3-L-Cit-OH
  N3-L-Cit-OH is a click chemistry reagent containing an azide group. N3-L-Cit-OH can be used to construct peptidomimetic ADC linkers using Click-chemistry[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-W108635

  N-[S-Trityl-L-cysteinyl]glycine
  N-[S-Trityl-L-cysteinyl]glycine is a cleavable ADC linker.

• HY-136045

  APN-PEG4-tetrazine
  APN-PEG4-tetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. APN-PEG4-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-151693

  H-L-Tyr(2-azidoethyl)-OH hydrochloride		99.88%
  H-L-Tyr(2-azidoethyl)-OH hydrochloride is a unnatural Tyrosine derivative. H-L-Tyr(2-azidoethyl)-OH hydrochloride is a click chemistry reagent containing an azide group[1][2]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-151839

  (2R,4R)-H-D-Pro(4-N3)-OH hydrochloride
  (2R,4R)-H-D-Pro(4-N3)-OH (hydrochloride) is a click chemistry reagent containing an azide group[1]. (2R,4R)-H-D-Pro(4-N3)-OH (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-126677

  Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA
  Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA is a double claevable 3-unit and 4-unit PEG linker for antibody-agent-conjugation (ADC). Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA also is a PROTAC linker that can be used in the synthesis of PROTACs.

• HY-130971

  Mal-PEG4-bis-PEG3-DBCO
  Mal-PEG4-bis-PEG3-DBCO is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Mal-PEG4-bis-PEG3-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-115524

  DBCO-NHS ester 2
  DBCO-NHS ester 2 is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 2 is a derivative of Dibenzylcyclooctyne (DBCO) used in copper-free click chemistry[1]. DBCO-NHS ester 2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-172287

  DBCO-PEG2-Val-Cit-PAB-MMAE
  DBCO-PEG2-Val-Cit-PAB-MMAE is an ADC linker featuring a DBCO group, a Val-Cit dipeptide, a PAB motif, and an MMAE warhead. The DBCO group is a click chemistry handle which readily reacts with azide groups, while the Val-Cit is a protease-cleavable dipeptide which releases the MMAE warhead into cells via an elimination mechanism.

• HY-151689

  (2S,3R)-Fmoc-Abu(3-N3)-OH
  (2S,3R)-Fmoc-Abu(3-N3)-OH is a click chemistry reagent containing an azide group. (2S,3R)-Fmoc-Abu(3-N3)-OH can be used for the research of various biochemical[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-136130

  N,N-Bis(PEG2-alkyne)-N-amido-PEG2-thiol
  N,N-Bis(PEG2-alkyne)-N-amido-PEG2-thiol is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. N,N-Bis(PEG2-alkyne)-N-amido-PEG2-thiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-148773

  MC-Gly-Gly-Phe-Boc
  MC-Gly-Gly-Phe-Boc is involved in the synthesis of antibody-drug conjugates (ADCs) to Trastuzumab (HY-P9907). MC-Gly-Gly-Phe-Boc can participate in cancer research[1].

• HY-151650

  N3-O2Oc-O2Oc-OH
  N3-O2Oc-O2Oc-OH is a click chemistry reagent containing an azide[1]. N3-O2Oc-O2Oc-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-126495

  Sulfo-LC-SPDP
  Sulfo-LC-SPDP is a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker.

• HY-130107

  Ald-Ph-NHS ester
  Ald-Ph-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC).

• HY-126349

  DTSSP Crosslinker		98.87%
  DTSSP Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151861

  N3-Aca-Aca-OH
  N3-Aca-Aca-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-151672

  Biotin-TEG-ATFBA		99.09%
  Biotin-TEG-ATFBA is a click chemistry reagent containing a perfluorophenylazide group. Biotin-TEG-ATFBA forms a highly stable azene intermediate that undergoes insertion and addition reactions (non-intermolecular rearrangement) in moderate to good yields after photolysis. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-126851

  Fluorescein-DBCO
  Fluorescein-DBCO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Fluorescein-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-156491

  Me-Tet-PEG9-NHS
  Me-Tet-PEG9-NHS is an ADC Linker containing 9 PEG units. Me-Tet-PEG9-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

• HY-151825

  Fmoc-L-Phe(4-NH-Poc)-OH
  Fmoc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent containing an azide group. Used as an orthogonally protected building block in solid-phase peptide synthesis. Poc-group can be further modified using Click-chemistry[1].

• HY-130184

  Azido-PEG8-NHS ester
  Azido-PEG8-NHS ester is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG8-NHS ester is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG8-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-130537

  Azido-PEG6-alcohol
  Azido-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG6-alcohol is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. Azido-PEG6-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-136136

  Fmoc-Val-Ala-PAB-PNP
  Fmoc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-126889

  Bis-PEG5-NHS ester
  Bis-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151820

  DBCO-PEG24-acid
  DBCO-PEG24-acid is a click chemistry reagent. DBCO-PEG24-acid is an analog of DBCO-Acid with PEG linker and a DBCO group. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain allows for increased water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research use only[1].

• HY-140098

  Boc-Cystamine
  Boc-Cystamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151833

  Methyltetrazine-amido-N-bis(PEG4-acid)
  Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent containing an azide group. Methyltetrazine-amido-N-bis(PEG4-acid) is a PEG derivative that contains a methyltetrazine group and two acid groups. This reagent can react with TCO-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. PEG linker increases the water solubility of the compound. Reagent grade, for research use only[1]. Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-W046471

  N-Boc-PEG4-bromide
  N-Boc-PEG4-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG4-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-136067

  DBCO-PEG4-HyNic
  DBCO-PEG4-HyNic is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG4-HyNic is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-157080

  Dibromomaleimide-C5-COOH		99.30%
  Dibromomaleimide-C5-COOH (DBM-C5-COOH) is a bifunctional dibromomaleimide (DBM) linker. Dibromomaleimide-C5-COOH can be used to connect MMAF and to synthesize ADC[1].

• HY-133434

  Aminoxyacetamide-PEG3-azide
  Aminoxyacetamide-PEG3-azide is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminoxyacetamide-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-133428

  DBCO-PEG3-TCO
  DBCO-PEG3-TCO is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG3-TCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DBCO-PEG3-TCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

• HY-136048

  Methylcyclopropene-PEG4-NHS
  Methylcyclopropene-PEG4-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-116186

  m-PEG5-MS
  m-PEG5-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG5-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-P1449A

  Boc-Gly-Gly-Phe-Gly-OH TFA		98.27%
  Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).

• HY-136096

  DBCO-PEG3 acetic-EVCit-PAB
  DBCO-PEG3 acetic-EVCit-PAB is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG3 acetic-EVCit-PAB is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-78931G

  Boc-Dap-NE (GMP)
  Boc-Dap-NE (GMP) is Boc-Dap-NE (HY-78931) produced by using GMP guidelines. Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.

• HY-151865

  (2S,4S)-H-L-Pro(4-N3)-OH
  (2S,4S)-H-L-Pro(4-N3)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-76104

  (2R,4R)-4-Hydroxypyrrolidine-2-carboxylic acid hydrochloride
  cis-4-Hydroxy-D-proline hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). cis-4-Hydroxy-D-proline hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

• HY-136127

  ALD-PEG4-OPFP
  ALD-PEG4-OPFP is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130298

  Amino-PEG11-OH
  Amino-PEG11-OH is non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG11-OH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-151638

  FMOC-3-azido-D-alanine
  FMOC-3-azido-D-alanine is a click chemistry reagent containing an azide group[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-129353

  Boc-Phe-(Alloc)Lys-PAB-PNP
  Boc-Phe-(Alloc)Lys-PAB-PNP is a used as a cleavable linker for antibody-drug conjugates (ADC).

• HY-126894

  Bis-PEG9-acid
  Bis- PEG9- acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis- PEG9- acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-23642

  Mal-amido-(CH2COOH)2		99.15%
  Mal-amido-(CH2COOH)2, compound 7a, is a maleimidoethyl-containing intermediate for hydrophilic ADC linker[1].

• HY-151749

  N3-D-Lys(Fmoc)-OH
  N3-D-Lys(Fmoc)-OH is a click chemistry reagent containing an azide group. Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompatible, rapid and highly specific in biological environments[1]. N3-D-Lys(Fmoc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-108379

  Boc-C2-Urea-bis(Boc)-C4-Urea-4-phenylacetic acid
  Boc-C2-Urea-bis(Boc)-C4-Urea-4-phenylacetic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-138488

  Biotin-PEG4-PFP ester
  Biotin-PEG4-PFP ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130943

  Methyltetrazine-PEG4-SS-PEG4-methyltetrazine
  Methyltetrazine-PEG4-SS-PEG4-methyltetrazine is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Methyltetrazine-PEG4-SS-PEG4-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-133430

  DBCO-PEG4-alkyne
  DBCO-PEG4-alkyne is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-W040222

  m-PEG11-Amine
  m-PEG11-Amino is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG11-Amine is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-151779

  N3-L-Dab(Fmoc)-OH
  N3-L-Dab(Fmoc)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-117104

  Hydroxy-PEG4-acid
  Hydroxy-PEG4-acid is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-W040214

  m-PEG4-Amine		98.80%
  m-PEG4-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG4-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-126518

  Cyclooctyne-O-PFP ester
  Cyclooctyne-O-PFP ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Cyclooctyne-O-PFP ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-156318

  SCO-PEG3-Maleimide
  SCO-PEG3-Maleimide is a cleavable ADC Linker containing 3 PEG units. SCO-PEG3-Maleimide can be used as a copper-free click chemical reagent for catalyst-free click reactions. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.

• HY-140102

  Azidoethyl-SS-propionic NHS ester
  Azidoethyl-SS-propionic NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azidoethyl-SS-propionic NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-136129

  N,N-Bis(PEG2-N3)-N-amido-PEG2-thiol
  N,N-Bis(PEG2-N3)-N-amido-PEG2-thiol is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. N,N-Bis(PEG2-N3)-N-amido-PEG2-thiol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-140118

  Fmoc-NH-ethyl-SS-propionic acid		99.53%
  Fmoc-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130572

  Azido-PEG5-acid
  Azido-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs, such as the conjugate CPT-APO (CPT: Camptothecin (HY-16560)). Azido-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1][2]. Azido-PEG5-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-W023121

  Fmoc-Gly-Gly-OH
  Fmoc-Gly-Gly-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151658

  H-L-Lys(N3-Gly)-OH
  H-L-Lys(N3-Gly)-OH is a click chemistry containing an azide group, a lysine derivative. H-L-Lys(N3-Gly)-OH can be incorporated into proteins for click modifications[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-126668

  Mal-PEG4-VC-PAB-DMEA
  Mal-PEG4-VC-PAB-DMEA is a cleavable ADC linker containing a Maleimide group. Mal-PEG4-VC-PAB-DMEA is used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151677

  (2R,4S)-Boc-D-Pro(4-N3)-OH
  (2R,4S)-Boc-D-Pro(4-N3)-OH is a click chemistry reagent containing an azide[1]. (2R,4S)-Boc-D-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-41063

  N-Boc-N-methyl-D-Valinol
  N-Boc-N-methyl-D-Valinol is an ADC linker with BOC protecting group.

• HY-126496

  PEG4-SPDP
  PEG4-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).

• HY-156727

  Val-Cit-PABC-Ahx-May
  Val-Cit-PABC-Ahx-May is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130211

  Azido-PEG5-alcohol
  Azido-PEG5-alcohol is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG5-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG5-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-141220

  m-PEG12-OH
  m-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

• HY-117519A

  Amino-Tri-(carboxyethoxymethyl)-methane hydrochloride
  Amino-Tri-(carboxyethoxymethyl)-methane hydrochloride is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(carboxyethoxymethyl)-methan hydrochloride is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1][2].

• HY-140111

  Propargyl-PEG1-SS-PEG1-propargyl
  Propargyl-PEG1-SS-PEG1-propargyl is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG1-SS-PEG1-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-130547

  BS2G Crosslinker disodium
  BS2G Crosslinker (disodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-115545

  DBCO-NHS ester 3
  DBCO-NHS ester 3 (Compound 12) is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 3 is a derivative of Dibenzylcyclooctyne (DBCO) obtained by activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC)[1][2]. DBCO-NHS ester 3 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-W002887

  N-Boc-cis-4-Hydroxy-D-proline
  N-Boc-cis-4-Hydroxy-D-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-Hydroxy-D-proline is also a alkyl chain-based PROTAC linker that can be used in the Synthesis of ADCs or PROTACs.

• HY-161022S

  FL118-C3-O-C-amide-C-NH2-d5
  FL118-C3-O-C-amide-C-NH2-d5 is a deuterium labeled FL118-C3-O-C-amide-C-NH2[1].

• HY-136432

  Mc-Gly-Gly-Phe-Gly-PAB-OH
  Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) is a cleavable ADC linker used for antibody-drug conjugates (ADCs).

• HY-151653

  H-D-Tyr(Propargyl)-OH
  H-D-Tyr(Propargyl)-OH is a click chemistry reagent containing an Azide[1]. H-D-Tyr(Propargyl)-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-156316

  SCO-PEG3-NH2
  SCO-PEG3-NH2 is a cleavable ADC Linker containing 3 PEG units. SCO-PEG3-NH2 can be used as a copper-free click chemical reagent for catalyst-free click reactions.

• HY-130084

  Mal-PEG2-VCP-NB		98.25%
  Mal-PEG2-VCP-NB is a claevable ADC linker containing a Maleimide group, 2-unit PEG and a VCP NB.

• HY-136077

  TCO-PEG3-aldehyde
  TCO-PEG3-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. TCO-PEG3-aldehyde is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

• HY-130503

  N-Boc-PEG1-bromide
  N-Boc-PEG1-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG1-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-W096127

  Biotin-sar-oh
  Biotin-sar-oh is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151744

  N3-TFBA-O2Oc
  N3-TFBA-O2Oc is a click chemistry reagent containing an azide group and an aryl group. Aryl azides are well-known precursors of nitrenes and have been introduced by Fleet et al. as versatile photoaffinity labeling agents to probe biological receptors. This type of compounds has been used as photo-cross linker (λmax=258 nm) in estrogen receptor studies and for direct surface coating of carbon and organic based polymers[1][2][3]. N3-TFBA-O2Oc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-129367

  NO2-SPP
  NO2-SPP is a cleavable linker that is used for making antibody-drug conjugate (ADC).

• HY-151645

  Alkyne-SNAP		99.32%
  Alkyne-SNAP (compound 3) is an Alkyne-conjugated benzylguanine. The benzylguanine moiety reacts with the SNAP-tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality for further click chemistry conjugation[1].

• HY-164731

  Mal-PEG12-DOTA
  Mal-PEG12-DOTA is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-112561

  Bis-PEG1-PFP ester
  Bis-PEG1-PFP ester is a non-cleavable (1 unit PEG) ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151683A

  H-L-Ser(Propargyl)-OH hydrochloride
  H-L-Ser(Propargyl)-OH hydrochloride is a click chemistry reagent containing an alkyne group[1].

• HY-151676

  Boc-L-Tyr(2-azidoethyl)-OH
  Boc-L-Tyr(2-azidoethyl)-OH (N-Boc-O-(2-azidoethyl)-L-tyrosine) is a click chemistry reagent containing an azide group[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-W800621

  Fmoc-PEG2-Val-Cit-PAB-OH
  Fmoc-PEG2-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The Fmoc protecting group may be removed with piperidine to reveal a primary amine for use in coupling reactions to form amides. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.

• HY-131082

  (R)-8-Azido-2-(Fmoc-amino)octanoic acid
  (R)-8-Azido-2-(Fmoc-amino)octanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. (R)-8-Azido-2-(Fmoc-amino)octanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-129378

  NO2-SPP-sulfo-Me
  NO2-SPP-sulfo-Me is a cleavable linker that is used for making antibody-drug conjugate (ADC)[1].

• HY-136125

  BCOT-PEF3-OPFP
  BCOT-PEF3-OPFP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. BCOT-PEF3-OPFP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-130928

  Tetrazine-Ph-OPSS
  Tetrazine-Ph-OPSS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetrazine-Ph-OPSS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-147021A

  MC-D-Val-Cit-PAB-PNP
  MC-D-Val-Cit-PAB-PNP is a agent-linker-ligand conjugates. MC-D-Val-Cit-PAB-PNP can be used for researching cancer, autoimmune diseases and infectious diseases[1].

• HY-148550

  MC-PEG2-NH2		98.14%
  MC-PEG2-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130825

  Bis-PEG13-NHS ester
  Bis-PEG13-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG13-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151658A

  H-L-Lys(N3-Gly)-OH hydrochloride
  H-L-Lys(N3-Gly)-OH hydrochloride is a click chemistry containing an azide group, a lysine derivative. H-L-Lys(N3-Gly)-OH hydrochloride can be incorporated into proteins for click modifications[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-156727A

  Val-Cit-PABC-Ahx-May TFA
  Val-Cit-PABC-Ahx-May TFA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-128890B

  DOTA-​NHS-ester TFA
  DOTA-​NHS-ester (TFA) is used as a linker for affibody molecules, and it can be employed in small animal positron emission tomography (PET), single photon emission computed tomography (SPECT), and CT scanning. DOTA-​NHS-ester can be used to label radiotracers or imaging probes for tumor detection[1].

• HY-130931

  Propargyl-NH-PEG3-C2-NHS ester
  Propargyl-NH-PEG3-C2-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-NH-PEG3-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-141123

  SPDP-C6-Gly-Leu-NHS ester
  SPDP-C6-Gly-Leu-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-W034597

  20-(tert-Butoxy)-20-oxoicosanoic acid
  20-(tert-Butoxy)-20-oxoicosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 20-(tert-Butoxy)-20-oxoicosanoic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs

• HY-W591479

  MC-val-ala-nhs ester
  MC-Val-Ala-NHS ester is a cleavable ADC linker with a malimide group and an NHS ester group. The Val-Ala linkers can be cleaved by Cathepsin B. Maleimide group is reactive toward thiol groups. MC is reactive with thiol moieties. The NHS ester is able to react specifically and efficiently with amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond.

• HY-130946

  NH2-C5-PEG4-N3-L-Lysine-PEG3-N3
  NH2-C5-PEG4-N3-L-Lysine-PEG3-N3 is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. NH2-C5-PEG4-N3-L-Lysine-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-130955

  Amino-bis-PEG3-TCO
  Amino-bis-PEG3-TCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Amino-bis-PEG3-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

• HY-140134

  PC Biotin-PEG3-NHS ester
  PC Biotin-PEG3-NHS ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-131990A

  MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH
  MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130364

  Fmoc-NH-PEG6-CH2COOH
  Fmoc-NH-PEG6-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG6-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-168548

  pAF-Oxime-PEG4-OH
  pAF-Oxime-PEG4-OH serves as a linker for Opadotina (HY-147248) and can be utilized in the preparation of antibody-drug conjugates (ADCs)[1].

• HY-130381

  Propargyl-PEG7-NHS ester
  Propargyl-PEG7-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG7-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG7-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-141141

  Boc-Val-Cit-PAB
  Boc-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-140152

  BCN-PEG3-VC-PFP ester
  BCN-PEG3-VC-PFP ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. BCN-PEG3-VC-PFP ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-133413

  DBCO-CONH-S-S-NHS ester		99.18%
  DBCO-CONH-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-CONH-S-S-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-151736

  N3-L-Dap(Boc)-OH
  N3-L-Dap(Boc)-OH is a click chemistry reagent containing an azide group. Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompatible, rapid and highly specific in biological environments[1]. N3-L-Dap(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-151714

  Biotin-MeTz
  Biotin-MeTz shiyi is a click chemistry reagent with a terminal methyltetrazine group. Biotin-MeTz shiyi, as a biotin derivative, can be used for the preparation of biotinylated conjugates[1].

• HY-W002680

  (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate		99.96%
  N-Boc-cis-4-hydroxy-D-proline methyl ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-hydroxy-D-proline methyl ester is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1

• HY-46572

  Benzyl 2-cyclopropyl-2-hydroxyacetate		98.43%
  Benzyl 2-cyclopropyl-2-hydroxyacetate is an intermediate in the synthesis of ADC linker.The linker composed of Benzyl 2-cyclopropyl-2-hydroxyacetate can be coupled to Exatecan (HY-13631) and combined with antibodies (such as antibody hu2F7)[1].

• HY-156810

  Fmoc-PEG4-GGFG-CH2-O-CH2-Cbz
  Fmoc-PEG4-GGFG-CH2-O-CH2-Cbz is a cleavable ADC linker containing 4 units of PEG, which can be used to synthesize active antibody conjugation molecules (ADC)[1].

• HY-151674

  N3-L-Cys(Trt)-OH (CHA)
  N3-L-Cys(Trt)-OH (CHA) is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-164275

  Alkyne-Val-Cit-PAB-OH
  Alkyne-Val-Cit-PAB-OH is a cleavable ADC linker.

• HY-136061

  BCN-PEG4-HyNic
  BCN-PEG4-HyNic is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. BCN-PEG4-HyNic is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-151830

  Me-PMeOx(50)-N3 (MW 4.3kDa)
  Me-PMeOx(50)-N3 (MW 4.3kDa) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-133584

  Bis-SS-C3-NHS ester
  Bis-SS-C3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130591

  Propargyl-PEG4-Br
  Propargyl-PEG4-Br is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-Br is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG4-Br is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-160981

  Mal-PEG4-VCP-NB
  Mal-PEG4-VCP-NB (Compound 17) is a degradable ADC linker containing a maleimide group, 4 PEG units and VCP NB[1].

• HY-130222

  Mal-PEG2-Val-Cit-PAB-OH		99.49%
  Mal-PEG2-Val-Cit-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-Val-Cit-PAB-OH also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.

• HY-136078

  Tetrazine-diazo-PEG4-biotin
  Tetrazine-diazo-PEG4-biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetrazine-diazo-PEG4-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-133432

  DBCO-PEG4-SS-TCO
  DBCO-PEG4-SS-TCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG4-SS-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

• HY-156475

  Me-Tet-PEG2-COOH
  Me-Tet-PEG2-COOH is an ADC Linker containing 2 PEG units. Me-Tet-PEG2-COOH can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

• HY-W019939

  Hydroxy-PEG10-Boc
  Hydroxy-PEG10-Boc is extacted from patent CN108707228 (example 0024)[1]. Hydroxy-PEG10-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG10-Boc can be conjugated to Paclitaxel (HY-B0015) or docetaxel (HY-B0011)[2].

• HY-42618

  Azido-PEG4-CH2-Boc
  Azido-PEG4-CH2-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG4-CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG4-CH2-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-135964

  (2-pyridyldithio)-PEG4 acid
  (2-pyridyldithio)-PEG4 acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-148425

  Mal-amide-PEG8-Val-Ala-PAB-PNP		99.60%
  Mal-amide-PEG8-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-W019213

  cis-4-Hydroxy-L-proline hydrochloride
  cis-4-Hydroxy-L-proline hydrochloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). cis-4-Hydroxy-L-proline hydrochloride is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

• HY-130475

  Azido-PEG9-acid
  Azido-PEG9-acid is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG9-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Azido-PEG9-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-151643

  beta-Glc-TEG-Alkyne
  beta-Glc-TEG-Alkyne is a click chemistry reagent containing an alkynes group. beta-Glc-TEG-Alkyne can be used for the research of various biochemical[1].

• HY-151679

  Fmoc-L-Lys(4-N3-Z)-OH
  Fmoc-L-Lys(4-N3-Z)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Lys(4-N3-Z)-OH acts as Lysine building-block for SPPS containing an Azide moiety as a bioorthogonal ligation handle, an infrared probe and a photo-affinity reagent. It can be decaged by trans-cyclooctenols via a strain-promoted 1,3-dipolar cycloaddition[1][2]. Fmoc-L-Lys(4-N3-Z)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-140101

  Azido-C2-SS-PEG2-C2-acid
  Azido-C2-SS-PEG2-C2-acid is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-C2-SS-PEG2-C2-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-169353

  Mal-Exo-EEVC
  Mal-Exo-EEVC is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC)[1].

• HY-118759

  DSP Crosslinker
  DSP Crosslinker is a cleavable ADC linker, used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151683

  H-L-Ser(Propargyl)-OH
  H-L-Ser(Propargyl)-OH is a click chemistry reagent containing an alkyne group[1].

• HY-136050

  TCO-PEG3-Biotin		99.90%
  TCO-PEG3-Biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. TCO-PEG3-Biotin is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

• HY-131087

  Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc
  Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-W108137

  Boc-Gly-Sar-OH
  Boc-Gly-Sar-OH is a cleavable ADC linker.

• HY-126533

  PDP-C1-Ph-Val-Cit
  PDP-C1-Ph-Val-Cit is a cleavable ADC linker used for antibody-drug conjugates (ADCs).

• HY-128947

  CL2 Linker
  CL2 Linker is a cleavableADC linker. CL2-SN-38 and CL2A-SN-38 are equivalent in agent substitution (~6), cell binding (Kd ~1.2 nM), cytotoxicity (IC50 ~2.2 nM), and serum stability in vitro (t1/2 ~20 hours)[1][2].

• HY-156315

  SCO-PEG2-NH2
  SCO-PEG2-NH2 is a cleavable ADC Linker containing 2 PEG units. SCO-PEG2-NH2 can be used as a copper-free click chemical reagent for catalyst-free click reactions.

• HY-151783A

  DAPOA (DCHA)
  DAPOA DCHA is a click chemistry reagent containing an azide. DAPOA DCHA can be used in peptide synthesis as a linker that can be further modified at the azido-groups using Staudinger ligation or click-chemistry. This material can be used as a building block for dendrimeric structures[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-140127

  Azide-C2-SS-C2-biotin		98.79%
  Azide-C2-SS-C2-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azide-C2-SS-C2-biotin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-126512

  Propargyl-C2-NHS ester
  Propargyl-C2-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC). Propargyl-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-151789

  Sulfo DBCO-TFP Ester
  Sulfo DBCO-TFP Ester is a water-soluble, sulfo-containing click chemistry reagent. Sulfo DBCO-TFP Ester enables simple and efficient incorporation of sulfo-DBCO moieties onto amine-containing molecules[1].

• HY-151768

  H2N-PEG2-N3 (TosOH)
  H2N-PEG2-N3 (TosOH) is a click chemistry reagent containing an Azide. N3-PEG2-Amine is used as a Click-chemistry linker in various applications[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-133549

  NO2-SPDMV-sulfo
  NO2-SPDMV-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130094

  NHPI-PEG2-C2-Pfp ester
  NHPI-PEG2-C2-Pfp ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-151682

  H-L-Lys(Norbornene-methoxycarbonyl)-OH
  H-L-Lys(Norbornene-methoxycarbonyl)-OH, a norbornene-derivatized lysine, can be click-functionalized. H-L-Lys(Norbornene-methoxycarbonyl)-OH can be used for the mild and selective modification of proteins in a copper-free click reaction[1].

• HY-W019798

  NH2-PEG8-acid
  NH2-PEG8-acid is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. NH2-PEG8-acid also is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].

• HY-W011277

  Fmoc-azetidine-3-carboxylic acid		99.86%
  Fmoc-azetidine-3-carboxylic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

• HY-151649

  Biotin-PEG(4)-SS-Alkyne
  Biotin-PEG(4)-SS-Alkyne is a click chemistry reagent containing an alkyne group. Biotin-PEG(4)-SS-Alkyne can be used for the research of various biochemical[1].

• HY-131833

  Fmoc-Gly-Gly-Phe-OH
  Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-156311

  BCN-endo-PEG2-maleimide
  BCN-endo-PEG2-maleimide is an ADC Linker containing 4 PEG units. BCN-endo-PEG2-maleimide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.

• HY-141144

  OPSS-Val-Cit-PAB-OH
  OPSS-Val-Cit-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151826

  Fmoc-D-Lys(pentynoyl)-OH
  Fmoc-D-Lys(pentynoyl)-OH is a click chemistry reagent containing an azide group. Used to introduce alkyne functionality into peptides that can be further modified using Click-chemistry[1][2].

• HY-117079

  N-Boc-N-bis(PEG2-OH)
  N-Boc-N-bis(PEG2-OH) is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-N-bis(PEG2-OH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151684

  Boc-Ser(O-propargyl)-OH
  Boc-Ser(O-propargyl)-OH is a click chemistry reagent containing an alkynes group. Boc-Ser(O-propargyl)-OH can be used for the research of various biochemical[1].

• HY-151743

  N3-Cystamine-Suc-OSu
  N3-Cystamine-Suc-OSu is a click chemistry reagent containing an azide group. N3-Cystamine-Suc-OSu can be used for the research of various biochemical[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-128940

  EC089
  EC089 is a cleavable linker used in conjugates of tubulysins and folates, and extracted from patent WO2011069116A1[1].

• HY-133408

  4-Methyl-4-(methyldisulfanyl)pentanoic acid		99.97%
  4-Methyl-4-(methyldisulfanyl)pentanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-132159

  MC-AAA-NHCH2OCH2COOH		98.56%
  MC-AAA-NHCH2OCH2COOH (compound 20) is a cleavable ADC linker that is used for making antibody-drug conjugate (ADC)[1].

• HY-136075

  HyNic-PEG4-alkyne
  HyNic-PEG4-alkyne is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. HyNic-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-79369R

  Succinic anhydride (Standard)
  Succinic anhydride (Standard) is the analytical standard of Succinic anhydride. This product is intended for research and analytical applications. Succinic anhydride is a cyclic anhydride and a nonclaevable ADC linker extracted from patent WO2009064913A1. Succinic anhydride can react with compound 4 of the patent to link the proagent to an amine or hydroxy 1 group of a targeting polypeptide[1].

• HY-151829

  Fmoc-L-Asn(EDA-N3)-OH
  Fmoc-L-Asn(EDA-N3)-OH is a click chemistry reagent containing an azide group. This building block is reported in literature for the modification of Amanitin via Click Chemistry. Alpha-Amanitin is the deadliest member of the amatoxin peptide family produced by the death-cap mushroom A. phalloides. It is an orally available, rigid, bicyclic octapeptide and one of the most lethal known natural products (LD50 = 50-100 μg/kg) acting as highly selective allosteric inhibitor of the RNA polymerase II[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-140099

  Amino-ethyl-SS-PEG3-NHBoc
  Amino-ethyl-SS-PEG3-NHBoc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-126513

  Propargyl-PEG1-NHS ester
  Propargyl-PEG1-NHS ester is a nonclaevable 1-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-PEG1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-158135

  Val-Cit-PAB-DEA-COOH
  Val-Cit-PAB-DEA-COOH (compound 17) is an ADC linker that can be used in the synthesis of ADCs[1].

• HY-138521

  Azido-C6-OH
  Azido-C6-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-C6-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-126670

  mDPR(Boc)-Val-Cit-PAB
  mDPR(Boc)-Val-Cit-PAB is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC)[1].

• HY-148067A

  XMT-1519 conjugate-1 TFA
  XMT-1519 conjugate-1 (compound 31) TFA is a linker for the HER-2 monoclonal antibody XMT-1519, which can be used to synthesize ADC and increase anti-tumor activity[1].

• HY-151669

  Fmoc-D-Aha-OH
  Fmoc-D-Aha-OH is a click chemistry reagent containing an azide[1]. Fmoc-D-Aha-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-117409

  Aminoethyl-SS-ethylalcohol
  Aminoethyl-SS-ethylalcohol is a glutathione cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-160234

  mc-vc-PAB-PBD
  mc-vc-PAB-PBD is a drug linker for the preparation of TDC and ADC[1].

• HY-141142

  Boc-Val-Cit-PAB-PNP		99.55%
  Boc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130945

  Tetrazine-PEG5-SS-amine
  Tetrazine-PEG5-SS-amine is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetrazine-PEG5-SS-amine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-130970

  Amino-PEG4-bis-PEG3-methyltetrazine
  Amino-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Amino-PEG4-bis-PEG3-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-139353

  Fmoc-Phe-Lys(Boc)-PAB
  Fmoc-Phe-Lys(Boc)-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-W800623

  Fmoc-PEG6-Val-Cit-PAB-OH
  Fmoc-PEG6-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The Fmoc protecting group may be removed with piperidine to reveal a primary amine which may be used in coupling reactions to form amides. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.

• HY-141284

  Gly-Gly-Gly-PEG4-methyltetrazine
  Gly-Gly-Gly-PEG4-methyltetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151793

  2-Azidoethyl β-D-lactoside
  beta-Lac-EO-N3 is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-101157

  Propargyl-PEG5-acid
  Propargyl-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG5-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-W879048

  DBCO-PEG24-Maleimide
  DBCO-PEG24-Maleimide contains a maleimide and a DBCO group. DBCO-PEG24-Maleimide can be used for thiol-containing biomolecule conjugations. DBCO-PEG24-Maleimide can be used in click chemistry with azide-bearing biomolecules[1].

• HY-164929

  PTAD-PEG8-azide		99.77%
  PTAD-PEG8-azide is a cleavable ADC linker containing an azide group. PTAD-PEG8-azide can be used in the synthesis of antibody-drug conjugates (ADCs).

• HY-136047

  Methylcyclopropene-PEG3-amine
  Methylcyclopropene-PEG3-amine is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-128929

  Fmoc-PEA		99.47%
  Fmoc-PEA (Example 1-2) is a used as a cleavable linker for antibody-drug conjugates (ADC)[1].

• HY-156312

  Me-Tet-PEG8-Maleimide
  Me-Tet-PEG8-Maleimide is an ADC Linker containing 8 PEG units. Me-Tet-PEG8-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.

• HY-W731085

  MC-GGFG-NH-CH2-O-CH2-(s-cyclopropane)-COOH
  MC-GGFG-NH-CH2-O-CH2-(s-cyclopropane)-COOH is an ADC linker that can be combined with the cytotoxic Camptothecin (HY-16560) to form an ADC-related drug-linker conjugate (Drug- Linker Conjugates for ADC).MC-GGFG-NH-CH2-O-CH2-cyclopropane-COOH is conjugated to Camptothecin, which can further bind to the antibody Trastuzumab (HY-P9907) to form Antibody-Drug Conjugates (ADCs)[1].

• HY-151764

  N3-D-Orn(Boc)-OH
  N3-D-Orn(Boc)-OH is a Boc-protected pentanoic amino acid derivative, can be used as a click chemistry reagent and has been used to synthesis antibody-drug conjugates (ADC)[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-133435

  Aminooxy-amido-PEG4-propargyl
  Aminooxy-amido-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-amido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-157737

  GVSKYG-PEG2-azide TFA
  GVSKYG-PEG2-azide (TFA) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

• HY-157338

  NHS-Ala-Ala-Asn-active metabolite
  NHS-Ala-Ala-Asn-active metabolite is a cleavable antibody-drug conjugate (ADC) linker for synthesis of kinesin spindle protein (KSP)inhibitor[1].

• HY-44221

  MAC glucuronide linker-1		98.56%
  MAC glucuronide linker-1 is a claevable ADC linker for antibody-agent-conjugations (ADCs)[1].

• HY-157003

  (S)-TCO-PEG2-NH2
  (S)-TCO-PEG2-NH2 is an ADC Linker containing 2 PEG units. (S)-TCO-PEG2-NH2 can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.

• HY-140227

  m-PEG12-amine
  m-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG12-amine is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

• HY-129377

  Sulfo-SPP
  Sulfo-SPP is a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker.

• HY-130315

  Br-PEG4-C2-Boc
  Br-PEG4-C2-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-156495

  Biotin-PEG3-Me-Tet
  Biotin-PEG3-Me-Tet is an ADC Linker containing 3 PEG units. Biotin-PEG3-Me-Tet can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

• HY-140122

  THP-SS-alcohol
  THP-SS-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151727

  Norbornene-NHS
  Norbornene-NHS is a click chemistry reagent. Norbornene-NHS is a dienophile for conjugation via copper-free Click reaction with tetrazines[1].

• HY-151835

  DBCO-PEG24-NHS ester
  DBCO-PEG24-NHS ester is a click chemistry reagent. DBCO-PEG24-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only[1].

• HY-120903

  DBCO-C3-Acid
  DBCO-C3-Acid is a Click Chemistry intermediate used in the synthesis of antibody-drug conjugate (ADC) linker[1].

• HY-118808

  Propargyl-PEG2-NHBoc
  Propargyl-PEG2-NHBoc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-NHBoc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG2-NHBoc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-126673

  Mal-C2-Gly3-EDA
  Mal-C2-Gly3-EDA is a cleavable ADC linker containing a Maleimide group. Mal-C2-Gly3-EDA is used for making antibody-drug conjugate.

• HY-126527

  N3-PEG2-C2-PFP ester
  N3-PEG2-C2-PFP ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG2-C2-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-151845

  N3-PhAc-OH
  N3-PhAc-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-151856

  N3-1,4-cis-CHC-OH
  N3-1,4-cis-CHC-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-W039178

  Hydroxy-PEG4-(CH2)2-Boc
  Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 191). Hydroxy-PEG4-(CH2)2-Boc is also a PROTAC linker that can be used in the synthesis of PROTACs.

• HY-130975

  Boc-Val-Dil-Dap-Phe-OMe
  Boc-Val-Dil-Dap-Phe-OMe is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-47018

  BCN-HS-PEG2-VA-PABC-SG3199
  BCN-HS-PEG2-VA-PABC-SG3199 (Compound 4) is a pyrrolobenzodiazepine that can be used as a agent linker of antibody-drug conjugates (ADC)[1]. BCN-HS-PEG2-VA-PABC-SG3199 is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-130098

  Ald-Ph-amido-PEG3-C-COOH
  Ald-Ph-amido-PEG3-C-COOH is a noncleavable linker used for the antibody-drug conjugate (ADC).

• HY-151854

  4-(Azidomethyl)benzoic acid
  4-(Azidomethyl)benzoic acid is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-117519

  Amino-Tri-(carboxyethoxymethyl)-methane
  Amino-Tri-(carboxyethoxymethyl)-methane is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Amino-Tri-(carboxyethoxymethyl)-methan is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].

• HY-136101

  Bocaminooxyacetamide-PEG3-alkyne
  Bocaminooxyacetamide-PEG3-alkyne is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Bocaminooxyacetamide-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-136074

  Methyltetrazine-PEG4-aldehyde
  Methyltetrazine-PEG4-aldehyde is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Methyltetrazine-PEG4-aldehyde is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-140117

  Boc-aminooxy-ethyl-SS-propanol
  Boc-aminooxy-ethyl-SS-propanol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-49223

  diMal-O-CH2COOH		98.44%
  diMal-O-CH2COOH is a cleavable ADC linker.

• HY-40141

  1-Boc-azetidine-3-carboxylic acid
  1-Boc-azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Boc-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2]

• HY-138745

  Bis-sulfone-PEG3-Azide		99.42%
  Bis-sulfone-PEG3-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Bis-sulfone-PEG3-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-133550

  DMAC-SPDB
  DMAC-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-I0781

  Boc-Hyp-OH
  Boc-Hyp-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-Hyp-OH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2]

• HY-W008429

  m-PEG2-Amine
  m-PEG2-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG2-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-129372

  PDdB-Pfp
  PDdB-Pfp is a cleavable ADC linker used for the agents that target for the extracellular loop 1 (ECL1) of TM4SF1 (transmembrane 4 L6 family member 1)[1].

• HY-135418

  Fmoc-Asp-NH2		98.49%
  Fmoc-Asp-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-129526

  Mal-PEG3-NHS ester
  Mal-PEG3-NHS ester is a noncleavable ADC linker containing a Maleimide group. Mal-PEG3-NHS ester is used for making antibody-drug conjugate[1].

• HY-151766

  DACN(Tos,Suc-OH)
  DACN(Tos,Suc-OH) is a click chemistry reagent containing a cycloalkyne group. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. Such strain-promoted azide-alkyne cycloadditions (SPAAC) using cycloalkynes have served for reliable molecular conjugation in a broad range of fields. The nitrogens are used as connection points for a variety of functional units. DACNs possess high thermal and chemical stability along with comparable click reactivity[1].

• HY-126524

  N3-Ph-NHS ester
  N3-Ph-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-Ph-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-141358

  SPDP-PEG36-NHS ester
  SPDP-PEG36-NHS ester is a cleavable 36 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151666A

  6-Azido-D-lysine hydrochloride
  6-Azido-D-lysine hydrochloride is a click chemistry reagent containing an azide[1]. 6-Azido-D-lysine (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-19318B

  Fmoc-D-Val-Cit-PAB
  Fmoc-D-Val-Cit-PAB is a cleavable linker for antibody-agent-conjugation (ADC)[1].

• HY-N8577

  2,4-Dihydroxy-3-methoxyacetophenone
  2,4-Dihydroxy-3-methoxyacetophenone is a chemical agent[1].

• HY-160776

  Diazido-methyltetrazine tri-arm
  Diazido-methyltetrazine tri-arm is a polyvalent ADC linker and can be used for synthesis of ADCs[1].

• HY-120537

  m-PEG5-CH2COOH		99.00%
  m-PEG5-CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG5-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-156479

  Me-Tet-PEG3-NHBoc
  Me-Tet-PEG3-NHBoc is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

• HY-79584

  Propargyl-Tos		98.64%
  Propargyl-Tos is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-Tos is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-151682A

  H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride
  H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride, a norbornene-derivatized lysine, can be click-functionalized. H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride can be used for the mild and selective modification of proteins in a copper-free click reaction[1].

• HY-161022A

  FL118-C3-O-C-amide-C-NH2 formate
  FL118-C3-O-C-amide-C-NH2 format is an ADC linker for the synthesis of synthetic antibody conjugate active molecules (ADCs)..

• HY-145593

  Aminooxy-PEG2-BCN
  Aminooxy-PEG2-BCN is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-PEG2-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-151836

  (2S,3R)-H-Abu(3-N3)-OH hydrochloride
  (2S,3R)-H-Abu(3-N3)-OH (hydrochloride) is a click chemistry reagent containing an azide group[1]. (2S,3R)-H-Abu(3-N3)-OH (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-164210

  DBCO-PEG2-C2-acid
  DBCO-PEG2-C2-acid is an ADC Linker. DBCO-PEG2-C2-acid can be used to synthesize Antibody-Drug Conjugates (ADCs)[1].

• HY-W591272

  Me-Tet-PEG3-NH2
  Me-Tet-PEG3-NH2 is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-NH2 can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

• HY-151752

  Mal-AMCHC-N-Propargylamide
  Mal-AMCHC-N-Propargylamide is a click chemistry reagent containing an azide group. Mal-AMCHC-N-Propargylamide can be a bio-conjugation reagent for antibody-agent-conjugate synthesis using Click-Chemistry[1].

• HY-W129833

  H-Asp-Gly-OH
  H-Asp-Gly-OH is a cleavable ADC linker.

• HY-78736G

  Val-Cit-PAB-OSBT (GMP)
  Val-Cit-PAB-OSBT GMP is a GMP grade Val-Cit-PAB-OSBT (HY-78736). Val-Cit-PAB-OSBT is a degradable ADC linker, which is composed of the polypeptide Val-Cit-PAB and OSBT groups coupled together[1].

• HY-130972

  Amino-bis-PEG3-DBCO
  Amino-bis-PEG3-DBCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Amino-bis-PEG3-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-400191

  Fmoc-Gly-(d-Gly)-allyl propionate
  Fmoc-Gly-(d-Gly)-allyl propionate is a cleavable linker that can be used to synthesize Antibody-Drug Conjugates (ADCs).

• HY-141153

  Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP
  Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP is a cleavable linker for synthesis of antibody-drug conjugates (ADCs)[1].

• HY-141167B

  (S)-TCO-PEG4-NHS ester
  (S)-TCO-PEG4-NHS ester is an ADC linker containing 4 PEG units. (S)-TCO-PEG4-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.

• HY-130105

  Ald-Ph-amido-PEG1-C2-Pfp ester
  Ald-Ph-amido-PEG1-C2-Pfp ester is a nonclaevable 1-unit PEG linker for antibody-agent-conjugation (ADC).

• HY-154802

  TCO-GK-PEG4-NHS ester
  TCO-GK-PEG4-NHS ester is an ADC Linker, and can be used for synthesis of [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d. [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d binds with high affinity and immunoreactivity to HER2[1]. TCO-GK-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

• HY-126884

  DBCO-NHCO-PEG4-NH-Boc
  DBCO-NHCO-PEG4-NH-Boc is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-NH-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-NHCO-PEG4-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-151781

  Fmoc-L-Dap(Poc)-OH
  Fmoc-L-Dap(Poc)-OH is a click chemistry reagent containing an azide group. Amino acid building block suitable for side chain Click conjugation with standard protocols and together with tetrazine linkers in copper-free Click conjugation (Diels-Alder)[1].

• HY-126405

  SMPT		98.07%
  SMPT is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-W096148

  Biotin-C4-amide-C5-NH2
  Biotin-C4-amide-C5-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-129352

  Cbz-Phe-(Alloc)Lys-PAB-PNP
  Cbz-Phe-(Alloc)Lys-PAB-PNP is an cleavable linker for antibody-drug conjugates (ADC) design.

• HY-136087

  Mal-bis-PEG3-DBCO
  Mal-bis-PEG3-DBCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Mal-bis-PEG3-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-W800618

  NH2-PEG3-Val-Cit-PAB-OH
  NH2-PEG3-Val-Cit-PAB-OH is a cleavable ADC linker featuring a primary amine, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB group. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The primary amine is free to perform a wide variety of reactions such as coupling with carboxylic acids, reductive aminations with ketones or aldehydes, or other more specialized uses such as in SNAr reactions or heterocyclic chemistry. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery via an elimination mechanism within the PAB structure.

• HY-136079

  Methyltetrazine-PEG4-hydrazone-DBCO
  Methyltetrazine-PEG4-hydrazone-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Methyltetrazine-PEG4-hydrazone-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Methyltetrazine-PEG4-hydrazone-DBCO also contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-126525

  4-N3Pfp-NHS ester
  4-N3Pfp-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 4-N3Pfp-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-140139

  PC Alkyne-PEG4-NHS ester
  PC Alkyne-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. PC Alkyne-PEG4-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-129942

  S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate
  S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) and refers to the Alkyl-Chain composition. S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is the linker portions of the molecules employed for mAb attachment purposes[1].

• HY-136040

  Tetrazine-PEG4-SS-NHS
  Tetrazine-PEG4-SS-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetrazine-PEG4-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-140140

  PC Mal-NHS carbonate ester
  PC Mal-NHS carbonate ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-136085

  Amino-bis-PEG3-BCN
  Amino-bis-PEG3-BCN is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Amino-bis-PEG3-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-130930

  Acid-propionylamino-Val-Cit-OH
  Acid-propionylamino-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-133063

  Fmoc-NH-PEG8-CH2COOH		99.41%
  Fmoc-NH-PEG8-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG8-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-130939

  APN-PEG4-Amine hydrochloride
  APN-PEG4-Amine (hydrochloride) is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. APN-PEG4-Amine (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-130088

  Bis-​PEG2-​NHS ester
  Bis-PEG2-NHS ester is a nonclaevable 2-unit PEG linker for antibody-agent-conjugation (ADC).

• HY-151738

  Fmoc-Aeg(N3)-OH
  Fmoc-Aeg(N3)-OH is a click chemistry reagent containing an Azide. Alkylating the Nitrogen of an amide bond results in peptoid structures, which leads to conformational restrains, like N-methylation and allows backbone derivatisation. Altering cytotoxicity, bacterial cell selectivity and receptor pharmacology through formation of peptoid derivatives have been published for Cilengitide, Piscidin 1, and MC3, MC4 and MC5 receptor agonist. This building block enables design of macrocycles through intermolecular crosslinking or backbone stabilization through intermolecular ring-closure. This compound is a potential building block for the construction of (customized) peptide nucleic acids (PNAs) and for peptoid synthesis[1]. Fmoc-Aeg(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-151863

  alpha-GalNAc-TEG-N3		99.21%
  alpha-GalNAc-TEG-N3 is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-151654

  N3-D-Lys(Boc)-OH
  N3-D-Lys(Boc)-OH is a click chemistry reagent containing an Azide[1]. N3-D-Lys(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-126520

  N3-C2-NHS ester
  N3-C2-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-W019226

  Methyl 1-Cbz-azetidine-3-carboxylate
  Methyl 1-Cbz-azetidine-3-carboxylate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyl 1-Cbz-azetidine-3-carboxylate is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1

• HY-126668A

  Mal-PEG4-VC-PAB-DMEA TFA
  Mal-PEG4-VC-PAB-DMEA TFA is a degradable ADC linker containing a maleimide group and can be used to synthesize antibody conjugate active molecules (ADCs)[1].

• HY-156476

  Me-Tet-PEG2-NHS
  Me-Tet-PEG2-NHS is an ADC Linker containing 2 PEG units. Me-Tet-PEG2-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

• HY-W042654

  BnO-PEG6-OH
  BnO-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). BnO-PEG6-OH is also a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1][2].

• HY-151737

  Z-L-Dbu(N3)-OH
  Z-L-Dbu(N3)-OH is a click chemistry reagent containing an Azide[1]. Z-L-Dbu(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-140112

  Acid-PEG2-SS-PEG2-acid
  Acid-PEG2-SS-PEG2-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151760

  (2R,4S)-H-D-Pro(4-N3)-OH
  (2R,4S)-H-D-Pro(4-N3)-OH is a click chemistry reagent containing an azide group[1]. (2R,4S)-H-D-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-W800837

  t-Boc-N-amido-PEG4-Val-Cit
  t-Boc-N-amido-PEG4-Val-Cit is a protease-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit dipeptide. The Val-Cit dipeptide is cleavable by cell proteases and features a carboxylic acid which is free for coupling reactions with amines to form amides. The Boc can be removed under acidic conditions to reveal a free primary amine, which may be used in a variety of reactions such as coupling or reductive amination.

• HY-151761

  H-L-Lys(4-N3-Z)-OH hydrochloride		99.69%
  H-L-Lys(4-N3-Z)-OH hydrochloride is a click chemistry reagent containing an azide group. H-L-Lys(4-N3-Z)-OH hydrochloride contains a lysine-modified azide moiety and as a bioorthogonal ligation handle. H-L-Lys(4-N3-Z)-OH hydrochloride is an infrared probe and a photo-affinity reagent[1][2]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-156478

  Me-Tet-PEG4-NHBoc
  Me-Tet-PEG4-NHBoc is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

• HY-153672

  Amine-PEG3-Lys(PEG3-N3)-PEG3-N3
  Amine-PEG3-Lys(PEG3-N3)-PEG3-N3 (compound 5) is a branched linker that can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151678

  N3-L-Lys(Mtt)-OH
  N3-L-Lys(Mtt)-OH is a click chemistry reagent containing an azide group. N3-L-Lys(Mtt)-OH can introduce azide functions into the amino acid building block of peptide sequences at the N-terminal position. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-129637

  NH2-PEG5-OH
  NH2-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. NH2-PEG5-OH is also a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

• HY-W045822

  Fmoc-Lys(Pal-Glu-OtBu)-OH		99.93%
  Fmoc-Lys(Pal-Glu-OtBu)-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Lys(Pal-Glu-OtBu)-OH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

• HY-133542

  Dimethylamine-SPDB
  Dimethylamine-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151818

  12-Azido-dodecanoyl-OSu
  12-Azido-dodecanoyl-OSu is a click chemistry reagent containing an azide group. 12-Azido-dodecanoyl-OSu can be used as a hydrophobic bioconjugation linker. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-129311

  Tr-PEG6-OH
  Tr-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-W035376

  m-PEG6-CH2CH2CHO
  m-PEG6-CH2CH2CHO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG6-CH2CH2CHO is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

• HY-123687

  DBCO-Sulfo-NHS ester sodium
  DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-Sulfo-NHS ester (sodium) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-126976

  Propargyl-PEG5-amine
  Propargyl-PEG5-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG5-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-140104

  Azidoethyl-SS-ethylamine
  Azidoethyl-SS-ethylamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azidoethyl-SS-ethylamine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-145676E

  Sodium phenyl ethylamido hyaluronate（10% substitution）
  Sodium phenyl ethylamido hyaluronate (10% substitution) is a chemical agent. Sodium phenyl ethylamido hyaluronate (10% substitution) has 10% phenethylamine substitution. The molecular weight is 40-60WD.

• HY-156313

  Me-Tet-PEG4-NHS
  Me-Tet-PEG4-NHS is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

• HY-145620

  Zuvotolimod	Chemical	99.46%
  Zuvotolimod is a myeloid cell agonist compound-linker for antibody conjugate. Zuvotolimod can be used in the research of cancer and hepatitis[1][2].

• HY-151731

  N3-1,4-trans-CHC-OH
  N3-1,4-trans-CHC-OH is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-151853A

  N3-L-Leu-OH (BHA)
  N3-L-Leu-OH (BHA) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-140120

  Mal-NH-ethyl-SS-propionic acid		98.09%
  Mal-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-19318C

  Fmoc-D-Val-D-Cit-PAB		98.97%
  Fmoc-D-Val-D-Cit-PAB is a cleavable linker for antibody-agent-conjugation (ADC)[1].

• HY-124123

  Aminooxy-PEG4-alcohol
  Aminooxy-PEG4-alcohol is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-PEG4-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].

• HY-129370

  SPDB-sulfo
  SPDB-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) [1].

• HY-W008352

  Boc-NH-PEG4-CH2CH2NH2
  Boc-NH-PEG4-CH2CH2NH2 a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-NH-PEG4-CH2CH2NH2 is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-129377A

  Sulfo-SPP sodium
  Sulfo-SPP sodium a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker.

• HY-138506

  DBCO-S-S-acid
  DBCO-S-S-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-S-S-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-131833G

  Fmoc-Gly-Gly-Phe-OH (GMP)
  Fmoc-Gly-Gly-Phe-OH GMP is a GMP grade Fmoc-Gly-Gly-Phe-OH (HY-131833). Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130810

  DBCO-Sulfo-Link-biotin
  DBCO-Sulfo-Link-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-Sulfo-Link-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-169352

  Mal-Exo-EVC
  Mal-Exo-EVC is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC)[1].

• HY-145676A

  Sodium phenyl ethylamido hyaluronate（30% substitution）
  Sodium phenyl ethylamido hyaluronate (30% substitution) is a chemical agent. Sodium phenyl ethylamido hyaluronate (30% substitution) has 30% phenethylamine substitution. The molecular weight is 40 WD – 60WD.

• HY-117050

  PEG12-Tos
  Tos-PEG12 is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). PEG12-Tos is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

• HY-129360

  Ala-Ala-Asn-PAB
  Ala-Ala-Asn-PAB is a peptide cleavable ADC linker for antibody-drug conjugates (ADCs)[1].

• HY-W729138

  Fmoc-D-homoArg(Et)2-OH hydrochloride
  Fmoc-D-homoArg(Et)2-OH (hydrochloride) is a Fmoc-protected derivative of D-Homoarginine (HArg) that renders peptides and proteins resistant to proteolysis by trypsin. Fmoc-D-homoArg(Et)2-OH (hydrochloride) can be used as a cleavable ADC linker to synthesize antibody-drug conjugates (ADCs)[1].

• HY-W800617

  NH2-PEG1-Val-Cit-PAB-OH
  NH2-PEG1-Val-Cit-PAB-OH is a cleavable ADC linker intermediate featuring a primary amine, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB group. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The primary amine is free to perform a wide variety of reactions such as coupling with carboxylic acids, reductive aminations with ketones or aldehydes, or other more specialized uses such as in SNAr reactions or heterocyclic chemistry. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery via an elimination mechanism within the PAB structure.

• HY-151704

  ICG-alkyne		99.17%
  ICG-alkyne is a click chemistry reagent containing an azide group[1].

• HY-140119

  Fmoc-NH-ethyl-SS-propionic NHS ester
  Fmoc-NH-ethyl-SS-propionic NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-136097

  Maleimide-PEG2-hydrazide TFA
  Maleimide-PEG2-hydrazide (TFA) is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151703

  Boc-D-Lys(N3)-OH
  Boc-D-Lys(N3)-OH is a Boc-protected amino acid derivative, can be used as a click chemistry reagent and an intermediate for synthesis of linkers[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-41062

  N-Boc-MeVal
  N-Boc-MeVal is an ADC linker with BOC protecting group[1].

• HY-130944

  Mal-PEG1-Val-Cit-PABC-OH
  Mal-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-138322

  N-trifluoroacetyl-β-alanyl chloride
  N-trifluoroacetyl-β-alanyl chloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-126676

  DBCO-(PEG2-Val-Cit-PAB)2
  DBCO-(PEG2-Val-Cit-PAB)2 is a dual cleavable ADC linker for antibody-drug conjugates (ADCs). DBCO-(PEG2-Val-Cit-PAB)2 is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DBCO-(PEG2-Val-Cit-PAB)2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-151763

  Boc-L-Aza-OH (CHA)
  Boc-L-Aza-OH CHA is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-151723

  H-D-Aha-OH hydrochloride
  H-D-Aha-OH (hydrochloride) is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-124386

  DBCO-NHCO-PEG4-amine
  DBCO-NHCO-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE (HY-15162) and antibody (e.g., DBCO-VCpAB MMAE and DBCO-TRX MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively)[1].

• HY-139107

  Biotin-PEG4-SS-azide
  Biotin-PEG4-SS-azide is a cleavable, biotin-labeled, ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Biotin-PEG4-SS-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-151696

  TCO-PEG3-maleimide
  TCO-PEG3-maleimide (TCO-PEG3-NEM) is a click chemistry reagent. TCO-PEG3-maleimide efficiently binds TCO (trans-cyclooctene) moiety to thiol-containing molecules (such as antibodies, cysteine-containing peptides)[1].

• HY-173161

  Mc-d-Val-d-Cit-PAB-PNP
  Mc-d-Val-d-Cit-PAB-PNP is a cleavable ADC linker that can be used for synthesizing antibody-drug conjugates (ADCs)[1].

• HY-140930

  Diazo Biotin-PEG3-DBCO
  Diazo Biotin-PEG3-DBCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Diazo Biotin-PEG3-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-W055861

  Fmoc-NH-PEG1-CH2COOH		99.91%
  Fmoc-NH-PEG1-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG1-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-147021

  MC-Val-D-Cit-PAB-PNP
  MC-Val-D-Cit-PAB-PNP is a cleavable peptide linker molecule used in the synthesis of antibody-drug conjugates (ADCs). MC-Val-D-Cit-PAB-PNP contains a maleimidocaproyl (Mc) group that can be conjugated to an antibody and a p-nitrophenol (PNP) group that allows the peptide to be linked to antitumor compounds.

• HY-W046348

  22-(tert-Butoxy)-22-oxodocosanoic acid
  22-(tert-Butoxy)-22-oxodocosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 22-(tert-Butoxy)-22-oxodocosanoic acid is also a alkyl chain-based PROTAC linker that can be used in t

• HY-133539

  Propargyl-C8-amido-PEG2-NHS ester
  Propargyl-C8-amido-PEG2-NHS ester is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-C8-amido-PEG2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-140125

  2-Hydroxyethyl disulfide mono-tosylate
  2-Hydroxyethyl disulfide mono-tosylate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-131833A

  Fmoc-Gly-Gly-D-Phe-OH
  Fmoc-Gly-Gly-D-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Gly-Gly-D-Phe-OH is the D-isomer of Fmoc-Gly-Gly-Phe-OH (HY-131833).

• HY-W008005

  Amino-PEG4-alcohol
  Amino-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Amino-PEG4-alcohol is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

• HY-156319

  BCN-exo-PEG2-NH2
  BCN-exo-PEG2-NH2 is an ADC Linker containing 2 PEG units. BCN-exo-PEG2-NH2 contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.

• HY-W800619

  NH2-PEG4-Val-Cit-PAB-OH
  NH2-PEG4-Val-Cit-PAB-OH is a cleavable ADC linker featuring a primary amine, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB group. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The primary amine is free to perform a wide variety of reactions such as coupling with carboxylic acids, reductive aminations with ketones or aldehydes, or other more specialized uses such as in SNAr reactions or heterocyclic chemistry. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery via an elimination mechanism within the PAB structure.

• HY-130953

  Mal-PEG4-bis-PEG3-methyltetrazine
  Mal-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Mal-PEG4-bis-PEG3-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-126531

  DMAC-PDB
  DMAC-PDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151662

  4-Azido-2,3,5,6-tetrafluorobenzoic Acid
  4-Azido-2,3,5,6-tetrafluorobenzoic Acid (N3-TFBA) is a click chemistry reagent containing an azide group. 4-Azido-2,3,5,6-tetrafluorobenzoic Acid is a complex with FAM-labeled DNA probe. 4-Azido-2,3,5,6-tetrafluorobenzoic Acid can be used as versatile photoaffinity labeling agents to probe biological receptors. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-126893

  Bis-PEG8-acid
  Bis-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-132251

  MCC
  MCC is non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as MCC-DM1[1].

• HY-130095

  NHPI-PEG2-C2-NHS ester		98.23%
  NHPI-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-130827

  Bis-PEG21-NHS ester
  Bis-PEG21-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG21-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-140310

  TCO-PEG4-DBCO
  TCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. TCO-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. TCO-PEG4-DBCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

• HY-126517

  Cyclooctyne-O-NHS ester
  Cyclooctyne-O-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Cyclooctyne-O-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-151866

  (2S)-N3-HABA
  (2S)-N3-HABA is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-130377

  Propargyl-PEG8-bromide
  Propargyl-PEG8-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-bromide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG8-bromide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-163789

  Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide
  Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups[1].

• HY-156323

  BCN-exo-PEG4-NHS
  BCN-exo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-exo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.

• HY-W016591

  2,4-Diisopropylphenol
  2,4-Diisopropylphenol is a widely accepted chemical agent[1].

• HY-163675

  Maleimide-PEG8-Val-Ala-PAB
  Maleimide-PEG8-Val-Ala-PAB is an ADC linker composed of the cleavable Val-Ala-PAB (HY-125933) linker and the probe molecule Maleimide (HY-W007324). Maleimide-PEG8-Val-Ala-PAB can be used to connect Cetuximab (HY-P9905) monoclonal antibody and CDK inhibitor SNS-032 (HY-10008) to synthesize antibody-drug conjugates (ADCs)[1].

• HY-136036

  Tetrazine-SS-PEG4-Biotin
  Tetrazine-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetrazine-SS-PEG4-Biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-151673

  Poc-Cystamine
  Poc-Cystamine (compound PPA-cyst) is a click chemistry reagent, a cystamine building block derived from a propynyl group[1].

• HY-159794

  Azido-methyltetrazine di-arm linker		98.75%
  Azido-methyltetrazine di-arm linker is a multivalent ADC linker for the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-133436

  Boc-aminooxy-amide-PEG4-propargyl
  Boc-aminooxy-amide-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Boc-aminooxy-amide-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-129362

  Phe-Lys(Fmoc)-PAB
  Phe-Lys(Fmoc)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].

• HY-129360A

  Ala-Ala-Asn-PAB TFA
  Ala-Ala-Asn-PAB TFA is a peptide cleavable ADC linker for antibody-drug conjugates (ADCs)[1].

• HY-133585

  Bis-SS-C3-sulfo-NHS ester
  Bis-SS-C3-sulfo-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-129371

  SPDV		98.03%
  SPDV is a cleavable ADC linker used for diagnosis and treatment of cancer or B cell proliferative diseas.

• HY-151725

  N3-Pen-Dtpp
  N3-Pen-Dtpp is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-151841

  N3-L-Lys(Boc)-OH
  N3-L-Lys(Boc)-OH is a click chemistry reagent containing an azide group[1]. N3-L-Lys(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-139956

  Mal-amido-PEG9-Val-Ala-PAB-SG3200
  Mal-amido-PEG9-Val-Ala-PAB-SG3200 is a cleavable ADC linker conjugate used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151859A

  N3-Gly-Gly-OH (DCHA)
  N3-Gly-Gly-OH (DCHA) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-48668

  AcLys-PABC-VC-Aur0101 intermediate-1
  AcLys-PABC-VC-Aur0101 intermediate-1 is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate[1].

• HY-W002886

  N-Boc-cis-4-hydroxy-L-proline
  N-Boc-cis-4-hydroxy-L-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-hydroxy-L-proline is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2

• HY-151715

  N3-D-Dap(Fmoc)-OH		99.87%
  N3-D-Dap(Fmoc)-OH is a click chemistry reagent. N3-D-Dap(Fmoc)-OH can be used as a component for coupling by click reaction and as an orthogonally protected diaminocarboxylic acid derivative[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-100216

  SPDP
  SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1][2].

• HY-114995

  Tr-PEG2-OH		99.45%
  Tr-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Tr-PEG2-OH is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

• HY-133538

  4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene
  4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-136089

  Aminooxy-PEG2-bis-PEG3-BCN
  Aminooxy-PEG2-bis-PEG3-BCN is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-PEG2-bis-PEG3-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-151758

  Methyltetrazine-PEG12-NHS ester
  Methyltetrazine-PEG12-NHS ester is a click chemistry reagent containing an azide group. Methyltetrazine-PEG12-NHS ester reacts with compounds containing TCO to form stable covalent bonds[1].

• HY-42972G

  DBCO-acid (GMP)
  DBCO-acid GMP is a GMP grade DBCO-acid (HY-42972). DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690)[1]. DBCO-acid is a click chemistry reagent, itcontains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-W018154

  H-Glu-OtBu
  H-Glu-OtBu is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). H-Glu-OtBu is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2

• HY-151719

  Azidoacetic Acid
  Azidoacetic Acid (2-Azidoacetic acid) (compound 92-1) is a click chemistry reagent containing an azide group. Azidoacetic Acid can be used as a small molecule tool for the synthesis of PROTAC[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-79369

  Succinic anhydride
  Succinic anhydride is a cyclic anhydride and a nonclaevable ADC linker extracted from patent WO2009064913A1. Succinic anhydride can react with compound 4 of the patent to link the proagent to an amine or hydroxy 1 group of a targeting polypeptide[1].

• HY-151699

  6-Azidohexanoyl-Val-Cit-PAB-PNP
  6-Azidohexanoyl-Val-Cit-PAB-PNP is a click chemistry reagent that can be used to synthesis It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-154981

  Mal-L-Dap(Boc)-OSu
  Mal-L-Dap(Boc)-Osu is an ADC Linker, and can be used for synthesis of ADCs[1].

• HY-400356

  Glucocorticoid receptor agonist-1 phosphate Gly-Glu TFA		98.84%
  Glucocorticoid receptor agonist-1 phosphate Gly-Glu (TFA) is a cleavable linker, that can be used to synthesize Antibody-Drug Conjugates (ADCs).

• HY-151788

  MeO-PEG-alkyne (MW 750Da)
  MeO-PEG-alkyne (MW 750Da) is a click chemistry reagent containing an alkyne group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-W099352

  (2R,3S)-3-(tert-Butoxy)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)butanoic acid
  (2R,3S)-3-(tert-Butoxy)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)butanoic acid is an ADC linker.

• HY-151838

  (2S,3S)-H-Abu(3-N3)-OH hydrochloride
  (2S,3S)-H-Abu(3-N3)-OH (hydrochloride) is a click chemistry reagent containing an azide group[1]. (2S,3S)-H-Abu(3-N3)-OH (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-132163

  MP-PEG4-VK(Boc)G-OSu
  MP-PEG4-VK(Boc)G-OSu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130435

  DBCO-PEG4-amine
  DBCO-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG4-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG4-amine can be used in the synthesis of FPM-PEG4-DBCO (a homobifunctional azide-to-azide cross-linker)[1]. DBCO-PEG4-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-151730

  (Me)Tz-butanoic acid
  (Me)Tz-butanoic acid is a click chemistry reagent containing an azide. (Me)Tz-butanoic acid is tetrazine linker for conjugation via Diels-Alder-reaction, i.e. copper-free Click reaction with dienophiles[1]. (Me)Tz-butanoic acid is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-159668

  DL002
  DL002 is a ADC linker that can be used to synthesize antibody-drug conjugates containing BCL-2 family protein degraders, and it's used in tumor research[1].

• HY-42489

  N3-PEG3-CH2CH2-Boc
  N3-PEG3-CH2CH2-Boc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. N3-PEG3-CH2CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[2]. N3-PEG3-CH2CH2-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-44149

  m-C-tri(CH2-PEG1-NHS ester)
  m-C-tri(CH2-PEG1-NHS ester) is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151693A

  H-L-Tyr(2-azidoethyl)-OH
  H-L-Tyr(2-azidoethyl)-OH is a unnatural Tyrosine derivative. H-L-Tyr(2-azidoethyl)-OH is a click chemistry reagent containing an azide group[1][2]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-140500

  m-PEG10-acid
  m-PEG10-acid is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. m-PEG10-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].

• HY-170534

  Ac-EEVC-OH
  Ac-EEVC-OH is the linker, that can be used for synthesis of ADC molecule[1].

• HY-78736

  Val-Cit-PAB-OSBT		99.55%
  Val-Cit-PAB-OSBT is a degradable ADC linker, which is composed of the polypeptide Val-Cit-PAB and OSBT groups coupled together[1].

• HY-W250992

  Boc-L-Lys(N3)-OH (CHA)
  Boc-L-Lys(N3)-OH CHA is a click chemistry reagent containing an azide[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-151707

  DACN(Tos,Ns)
  DACN(Tos,Ns) is a click chemistry reagent containing an cyclic alkyne group[1].

• HY-145367

  Ala-CO-amide-C4-Boc
  Ala-CO-amide-C4-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-42745

  m-PEG2-Tos
  m-PEG2-Tos is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG2-Tos is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

• HY-141663

  2',3'-cGAMP-C2-SH
  2',3'-cGAMP-C2-SH is a cyclic di-nucleotide (CDN) that can be conjugated to antibodies or antigen-binding fragments targeting specific antigens in the microenvironment of diseased cells or tissue[1].

• HY-136053

  Tetrazine-PEG4-biotin		99.34%
  Tetrazine-PEG4-biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetrazine-PEG4-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-140110

  Propargyl-PEG1-SS-PEG1-PFP ester
  Propargyl-PEG1-SS-PEG1-PFP ester is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG1-SS-PEG1-PFP ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-144628

  Fmoc-Asn-Pro-Val-PABC-PNP		99.34%
  Fmoc-Asn-Pro-Val-PABC-PNP (compound 6) is a potent ADC Linker[1].

• HY-140025

  Propargyl-PEG4-CH2CO2-NHS
  Propargyl-PEG4-CH2CO2-NHS (compound P-7) is a PEG derivative containing a propargyl group and an NHS group. Propargyl-PEG4-CH2CO2-NHS is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG4-CH2CO2-NHS is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups[1].

• HY-130166

  Amino-PEG9-acid
  Amino-PEG9-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Amino-PEG9-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151671

  Fmoc-L-MeLys(N3)-OH
  Fmoc-L-MeLys(N3)-OH is a click chemistry reagent containing an azide. Fmoc-L-MeLys(N3)-OH is a SPPS building-block for the introduction of N-Me-Lys that can be modified at the N3-group using Click-chemistry[1]. Fmoc-L-MeLys(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-77475

  1-Cbz-3-Hydroxyazetidine		99.89%
  1-Cbz-3-Hydroxyazetidine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Cbz-3-Hydroxyazetidine is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

• HY-128938A

  EC1167 hydrochloride		98.04%
  EC1167 hydrochloride is the linker for EC1169. EC1169 is prostate-specific membrane antigen targeting-tubulysin conjugate. EC1169 hydrochloride has the potential to treat recurrent metastatic, castration-resistant prostate cancer (MCRPC)[1].

• HY-133573

  Cyclooctyne-O-amido-PEG2-PFP ester
  Cyclooctyne-O-amido-PEG2-PFP ester is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Cyclooctyne-O-amido-PEG2-PFP ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-130169

  Azido-PEG9-amine
  Azido-PEG9-amine is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG9-amine is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG9-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-151848

  (2R,4R)-Boc-D-Pro(4-N3)-OH
  (2R,4R)-Boc-D-Pro(4-N3)-OH is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-W004868

  1-Cbz-azetidine-3-carboxylic acid
  1-Cbz-azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Cbz-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]

• HY-151767

  Boc-Cystamine-Poc
  Boc-Cystamine-Poc (compound H4) is a click chemistry reagent with cystamine building block[1].

• HY-126672

  Mal-PEG4-Val-Cit-PAB		98.87%
  Mal-PEG4-Val-Cit-PAB is a cleavable ADC linker containing a Maleimide group. Mal-PEG4-Val-Cit-PAB is used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-120770

  DBCO-PEG4-Maleimide		98.02%
  DBCO-PEG4-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG4-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-126497

  LC-PEG8-SPDP
  LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].

• HY-133066

  m-PEG6-NHS ester
  m-PEG6-NHS ester is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG6-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.

• HY-129365

  SNPB		98.01%
  SNPB is a cleavable linker that is used for making antibody-drug conjugate (ADC).

• HY-135977

  DBCO-SS-aldehyde
  DBCO-SS-aldehyde is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-SS-aldehyde is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-140213

  Azido-PEG2-C2-amine
  Azido-PEG2-C2-amine (N3-PEG2-CH2CH2NH2) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG2-C2-amine is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. Azido-PEG2-C2-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-160982

  Mal-PEG3-VCP-NB
  Mal-PEG3-VCP-NB (Compund 25c) is a degradable ADC linker containing a maleimide group, 3-unit PEG and VCP NB[1].

• HY-128927

  Mc-Leu-Gly-Arg
  Mc-Leu-Gly-Arg is a cleavable ether linker for antibody-drug conjugates (ADC) design.

• HY-151823

  8-Azido-octanoyl-OSu
  8-Azido-octanoyl-OSu is a click chemistry reagent containing an azide group. Used as a building block to introduce 8-azidooctanoic acid (CAS 217180-76-2) fragment. This fragment is used for further modifications using Click-chemistry (CuAAC), as a protected aminogroup or is used in physico-chemical investigations[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-130426

  Maleimido-tri(ethylene glycol)-propionic acid
  Maleimido-tri(ethylene glycol)-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Maleimido-tri(ethylene glycol)-propionic acid is used for the preparation of neolymphostin-based ADC precursors for site-specific cysteine mutant trastuzumab-A114C conjugation[1]. Maleimido-tri(ethylene glycol)-propionic acid also can be used as a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

• HY-151748

  N3-L-Orn(Fmoc)-OH
  N3-L-Orn(Fmoc)-OH is a Fmoc-protected ornithine derivative, can be used as a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-156320

  BCN-exo-PEG2-maleimide
  BCN-exo-PEG2-maleimide is an ADC Linker containing 2 PEG units. BCN-exo-PEG2-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.

• HY-151754

  DACN(Tos2,6-OH)
  DACN(Tos2,6-OH) is a click chemistry reagent containing an Azide. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. The reactivity of an alkyne heavily depends on the electronic and steric characteristics of the substituents as well as structural strain. In comparison to nonbent acyclic alkynes, cyclononyne alkynes show remarkably high reactivity. Such strain-promoted azide-alkyne cycloadditions (SPAAC) using cycloalkynes have served for reliable molecular conjugation in a broad range of fields. The nitrogens are used as connection points for a variety of functional units. In comparison to cyclooctynes, DACNs possess high thermal and chemical stability along with comparable click reactivity[1]. DACN(Tos2,6-OH) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-164367

  Mal-Bal-Ph(β-D-Glucose)-7-MAD-MDCPT		98.19%
  DBCO-PEG2-C2-acid is an ADC Linker. DBCO-PEG2-C2-acid can be used to synthesize Antibody-Drug Conjugates (ADCs)[1].

• HY-126515

  Propargyl-O-C1-amido-PEG4-C2-NHS ester
  Propargyl-O-C1-amido-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-O-C1-amido-PEG4-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-130379

  Propargyl-PEG8-acid
  Propargyl-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). The ADCs can be used in bacterial infections caused by Gram-negative bacteria[1]. Propargyl-PEG8-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-133583

  Propargyl-O-C1-amido-PEG3-C2-NHS ester
  Propargyl-O-C1-amido-PEG3-C2-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-O-C1-amido-PEG3-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-130977

  Tetrazine-PEG4-amine hydrochloride
  Tetrazine-PEG4-amine (hydrochloride) is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetrazine-PEG4-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-120258

  Tr-PEG3-OH		99.55%
  Tr-PEG3-OH is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-140109

  Propargyl-PEG1-SS-PEG1-acid
  Propargyl-PEG1-SS-PEG1-acid is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG1-SS-PEG1-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-131084

  DMAC-SPDB-sulfo
  DMAC-SPDB-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-78738G

  MC-Val-Cit-PAB (GMP)
  MC-Val-Cit-PAB GMP is a GMP grade MC-Val-Cit-PAB (HY-78738). MC-Val-Cit-PAB is an intermediate in the synthesis of VcMMAE (HY-15575), which is a Drug-Linker Conjugates for ADC. Monomethyl auristatin E can be used to inhibit Microtubule/Tubulin as ADC Cytotoxin.

• HY-151784

  Boc-D-Aza-OH
  Boc-D-Aza-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-130385

  Propargyl-PEG6-NHS ester
  Propargyl-PEG6-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG6-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-136104

  Methyltetrazine-Maleimide
  Methyltetrazine-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Methyltetrazine-Maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-136141

  DBCO-PEG3-propionic EVCit-PAB
  DBCO-PEG3-propionic EVCit-PAB is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG3-propionic EVCit-PAB is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-126886

  Mal-PEG1-NHS ester
  Mal-PEG1-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG1-NHS ester is PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

• HY-111121

  cBu-Cit-OH
  cBu-Cit-OH (Mal-cyclobutane-1) is an ADC Linker that can be used to synthesize ADCs[1].

• HY-130150

  m-PEG5-succinimidyl carbonate
  m-PEG5-succinimidyl carbonate is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG5-succinimidyl carbonate is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.

• HY-130096

  Ald-Ph-amido-C2-nitrate
  Ald-Ph-amido-C2-nitrate (Example XXIVb) is a thiazolidine derivative, used as a noncleavable ADC linker[1].

• HY-148472A

  C2-Amide-C4-NH2
  C2-Amide-C4-NH2 is a potent linker[1].

• HY-126528

  N3-PEG3-C2-NHS ester
  N3-PEG3-C2-NHS ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-112560

  Bis-PEG2-PFP ester
  Bis-PEG2-PFP ester is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Bis-PEG2-PFP ester is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].

• HY-126516

  Propargyl-PEG4-NHS ester
  Propargyl-PEG4-NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-PEG4-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-115374

  m-PEG6-azide
  m-PEG6-azide is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-148080

  Indole-C2-amide-C2-NH2		99.42%
  Indole-C2-amide-C2-NH2 is a potent linker[1].

• HY-141379

  N-Bromoacetyl-β-alanine
  N-Bromoacetyl-β-alanine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-Bromoacetyl-β-alanine is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

• HY-141353

  SPDP-PEG12-acid
  SPDP-PEG12-acid is a cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130101

  Ald-Ph-amido-PEG4-C2-NHS ester		98.12%
  Ald-Ph-amido-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC).

• HY-156308

  Me-Tet-PEG4-Maleimide
  Me-Tet-PEG4-Maleimide is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.

• HY-133582

  Mal-amido-PEG3-C1-​NHS ester
  Mal-amido-PEG3-C1- NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-W011561

  Boc-NH-C6-Br
  Boc-NH-C6-Br is a non-cleavable linker used for antibody-drug conjugates (ADC)[1].

• HY-141169B

  (R,E)-TCO-PEG8-NHS ester
  (R)-TCO-PEG8-NHS ester is an ADC linker containing 8 PEG units. (R)-TCO-PEG8-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.

• HY-160714

  Fmoc-Ala-Ala-Ala-amide-C-O-C-COOH
  Fmoc-Ala-Ala-Ala-amide-C-O-C-COOH (Compound IM-3) is a cleavable ADC linker[1].

• HY-138387

  6-Azido-hexylamine
  6-Azido-hexylamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 6-Azido-hexylamine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-132973

  MC-Val-Cit-PAB-NH-C2-NH-Boc
  MC-Val-Cit-PAB-NH-C2-NH-Boc is a cathepsin cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-44234A

  Fmoc-Gly-Gly-D-Phe-OtBu		98.28%
  Fmoc-Gly-Gly-D-Phe-OtBu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Gly-Gly-D-Phe-OtBu is the R-isomer of Fmoc-Gly-Gly-Phe-OtBu (HY-44234)[1].

• HY-151639A

  (2S,4R)-H-L-Pro(4-N3)-OH hydrochloride
  (2S,4R)-H-L-Pro(4-N3)-OH (hydrochloride) is a click chemistry reagent containing an azide group. (2S,4R)-H-L-Pro(4-N3)-OH (hydrochloride) can be used for the research of various biochemical studies[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-W800624

  Boc-PEG2-Val-Cit-PAB-OH
  Boc-PEG2-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The Boc protecting group may be removed with acid to reveal a primary amine which may be used in coupling reactions to form amides. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.

• HY-112099

  Mc-Val-Cit-PAB-Cl
  Mc-Val-Cit-PAB-Cl is a cleavable ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay).

• HY-133579

  Ald-Ph-amido-PEG3-NHS ester
  Ald-Ph-amido-PEG3-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151787

  Fmoc-L-Lys(N3-Aca-DIM)-OH
  Fmoc-L-Lys(N3-Aca-DIM)-OH is a click chemistry reagent containing an azide group. Used as a SPPS building-block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-125933

  Val-Ala-PAB		99.54%
  Val-Ala-PAB is a cleavable ADC linker that can be used for ADCs synthesis[1].

• HY-151777

  N3-Gly-Gly-Gly-Gly-Gly-OH
  N3-Gly-Gly-Gly-Gly-Gly-OH is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-156310

  BCN-endo-PEG7-NH2
  BCN-endo-PEG7-NH2 is an ADC Linker containing 7 PEG units. BCN-endo-PEG7-NH2 contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

• HY-151849

  Z-L-Dap(N3)-OH
  Z-L-Dap(N3)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-W101718

  Fmoc-N-(2-Boc-aminoethyl)-Gly-OH		99.76%
  Fmoc-N-(2-Boc-aminoethyl)-Gly-OH is a Fmoc-protected glycine derivative that can be used in antibody agent coupling (ADC) synthesis. ADC consists of antibodies that are linked to ADC cytotoxins via ADC junctions[1].

• HY-W591336

  Alloc-Val-Ala-PAB-PNP
  Alloc-Val-Ala-PAB-PNP is a cleavable ADC linker.

• HY-42488

  Hydroxy-PEG3-(CH2)2-Boc
  Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196)[1]. Hydroxy-PEG2-(CH2)2-Boc is also a PROTAC linker that can be used in the synthesis of PROTACs.

• HY-140352

  Azide-PEG5-Tos
  Azide-PEG5-Tos is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azide-PEG5-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-136038

  Azido-PEG3-SSPy		98.62%
  Azido-PEG3-SSPy is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG3-SSPy is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-47812

  Cbz-D-Glu(Bn)-Gly-Gly-Gly-Gly
  Cbz-(D-Glu)Bn-Gly-Gly-Gly-Gly is a cleavable ADC linker.

• HY-W040231

  Fmoc-NH-PEG3-CH2CH2COOH
  Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG3-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-114816S

  N-butyryl-L-Homoserine lactone-d5
  N-butyryl-L-Homoserine lactone-d5 is the deuterium labeled N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm[1]. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa[2][3].

• HY-130175

  Fmoc-NH-PEG4-CH2COOH		99.11%
  Fmoc-NH-PEG4-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG4-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-78961

  6-Maleimidohexanoic acid N-hydroxysuccinimide ester
  6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS) is a heterobifunctional cross-linking reagent. EMCS is used as a unique and useful reagent for preparation of hapten conjugate and enzyme immunoconjugates[1].

• HY-42972

  DBCO-acid		99.71%
  DBCO-acid is a click chemistry reagent used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690). DBCO-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups[1][2][3][4].

• HY-147164

  MC-Gly-Gly-Phe-Gly-PAB-PNP		99.22%
  MC-Gly-Gly-Phe-Gly-PAB-PNP is a linker for synthesis anti-human EGFR antibody agent conjugate[1].

• HY-133427

  Propargyl-PEG4-hydrazide
  Propargyl-PEG4-hydrazide is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG4-hydrazide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-151851

  3-Azidopropanol
  3-Azidopropanol is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-132261

  AcBut		98.07%
  AcBut is a cleavable Ozogamicin linker used in the synthesis of Ozogamicin, a agent-linker conjugate for ADC[1].

• HY-W016429

  H-cis-Hyp-OMe hydrochloride
  H-cis-Hyp-OMe hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). H-cis-Hyp-OMe hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PR

• HY-129525A

  Sulfo-SIAB sodium
  Sulfo-SIAB sodium is a nonclaevable monovalent bilinker.

• HY-136107

  Fmoc-Phe-Lys(Trt)-PAB
  Fmoc-Phe-Lys(Trt)-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-W591286

  Alkyne-Val-Cit-PAB-PNP
  Alkyne-Val-Cit-PAB-PNP is a cleavable ADC linker.

• HY-130571

  m-PEG9-Amine
  m-PEG9-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG9-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-131990G

  MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (GMP)
  MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-131990). MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-79125

  Fmoc-Hyp(Bom)-OH
  Fmoc-Hyp(Bom)-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Hyp(Bom)-OH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs<

• HY-126526

  N3-PEG2-C2-NHS ester
  N3-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG2-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-W614632

  γ-Glu-Val-Gly		99.79%
  γ-Glu-Val-Gly is a cleavable ADC linker.

• HY-141169A

  (S,E)-TCO2-PEG8-NHS ester
  (S)-TCO-PEG8-NHS ester is an ADC linker containing 8 PEG units. (S)-TCO-PEG8-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.

• HY-126669

  Mal-PEG4-VA
  Mal-PEG4-VA is a cleavable ADC linker containing a Maleimide group. Mal-PEG4-VA is used for making antibody-drug conjugate.

• HY-P4192

  Fomc-Gly-Gly-Phe-Gly-OH		99.66%
  Fomc-Gly-Gly-Phe-Gly-OH (compound D5) can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit[1].

• HY-151747

  Chemical phosphorylation amidite
  Chemical phosphorylation amidite is a click chemical class ADC linker. Click chemistry has good biological orthogonality characteristics: biocompatible, fast and highly specific in the biological environment, and has great application potential in the binding between nucleic acids, lipids, proteins and other molecules[1].

• HY-130933

  Fmoc-Ala-Ala-Asn(Trt)-OH		99.80%
  Fmoc-Ala-Ala-Asn(Trt)-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130826

  Bis-PEG17-NHS ester
  Bis-PEG17-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG17-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130383

  Propargyl-PEG7-acid
  Propargyl-PEG7-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG7-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG7-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-151726

  Azido-PEG(4)-Val-Cit-PAB-PNP
  Azido-PEG(4)-Val-Cit-PAB-PNP is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-151739

  4-Pentynoyl-Val-Ala-PAB
  4-Pentynoyl-Val-Ala-PAB is a click chemical class ADC linker. Click chemistry has good biological orthogonality characteristics: biocompatible, fast and highly specific in the biological environment, and has great application potential in the binding between nucleic acids, lipids, proteins and other molecules[1].

• HY-129349

  Phe-Lys(Trt)-PAB
  Phe-Lys(Trt)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].

• HY-42974

  DBCO-PEG3-acid		98.35%
  DBCO-PEG3-acid is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG3-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups[1].

• HY-130828

  Bis-PEG25-NHS ester
  Bis-PEG25-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG25-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151785A

  H-L-Dbu(N3)-OH hydrochloride
  H-L-Dbu(N3)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-W040257

  NH2-PEG6-CH2CH2COOH
  NH2-PEG6-CH2CH2COOH is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). NH2-PEG6-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-77593

  (2R,4S)-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid
  N-tert-Butoxycarbonyl-trans-4-hydroxy-D-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-tert-Butoxycarbonyl-trans-4-hydroxy-D-proline is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

• HY-151795

  DACN(Tos) hydrochloride
  DACN(Tos) hydrochloride is a click chemistry reagent containing a cycloalkyne group. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions, such strain-promoted azide-alkyne cycloadditions (SPAAC) by using cycloalkynes. DACNs possesses high thermal and chemical stability along with comparable click reactivity. DACN(Tos) hydrochloride can be used for the research of molecular conjugation[1].

• HY-W000423

  DBCO-amine
  DBCO-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-136076

  TCO-PEG3-CH2-aldehyde
  TCO-PEG3-CH2-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. TCO-PEG3-CH2-aldehyde is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

• HY-156299

  NMS-P945
  NMS-P945 is an ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs). NMS-P945 is suitable for conjugation to mAbs with reproducible Drug Antibody Ratio (DAR) >3.5[1].

• HY-W071006

  PPC-NHS ester
  PPC-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130092

  NHPI-PEG3-C2-Pfp ester
  NHPI-PEG3-C2-Pfp ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-W190924

  Mal-amido-PEG8-val-gly
  Mal-amido-PEG8-Val-Gly is an ADC linker containing a maleimide group.

• HY-160408

  Mal-GGG-Bal-NHS ester
  Mal-GGG-Bal-NHS ester is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130293

  Propargyl-PEG4-CH2CH2-Boc
  Propargyl-PEG4-CH2CH2-Boc is a non-cleavable ADC linker that can be used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG4-CH2CH2-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-133543

  SPDP-sulfo
  SPDP-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-41541

  Tetraethylene glycol monotosylate
  Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetraethylene glycol monotosylate also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.

• HY-W051634

  Propargyl-PEG2-amine
  Propargyl-PEG2-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1][2]. Propargyl-PEG2-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-49484

  EGGGG-PEG8-amide-bis(deoxyglucitol)		98.90%
  EGGGG-PEG8-amide-bis(deoxyglucitol) is a cleavable ADC linker.

• HY-121805

  DBCO-​C6-​acid
  DBCO-C6-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-C6-acid can be used in the synthesis of carmaphycin analogues[1]. DBCO- C6- acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-157737A

  GVSKYG-PEG2-azide hydrochloride
  GVSKYG-PEG2-azide (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

• HY-136103

  DBCO-PEG4-Propionic-Val-Cit-PAB
  DBCO-PEG4-Propionic-Val-Cit-PAB is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG4-Propionic-Val-Cit-PAB is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-151717

  N1-Azido-spermine trihydrochloride
  N1-Azido-spermine [Spermine(HHHN3)] trihydrochloride is a click chemistry agent containing azide. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-78738

  MC-Val-Cit-PAB
  MC-Val-Cit-PAB is a cleavable ADC Linker that forms part of VcMMAE (HY-15575). VcMMAE is Drug-Linker Conjugates for ADCs. The ADC Cytotoxin in VcMMAE is MMAE, a tubulin polymerization inhibitor.

• HY-158199

  BCN-HS-PEG2-bis(PNP)
  BCN-HS-PEG2-bis(PNP) (Compound 62) is a p-nitrophenyl-containing ADC linker that can be used to further couple ADC cytotoxins with peptide linkers. BCN-HS-PEG2-bis(PNP) can conjugate with vc-PABC-MMAE (HY-15162) to form Drug-Linker Conjugates for ADC[1].

• HY-114816

  N-Butanoyl-L-homoserine lactone
  N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm[1]. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa[2][3].

• HY-20560

  (Ac)Phe-Lys(Alloc)-PABC-PNP
  (Ac)Phe-Lys(Alloc)-PABC-PNP is an useful cleavable chemical linker in antibody drug conjugates.

• HY-151855

  Azido Myristic Acid
  Azido Myristic Acid is a click chemistry reagent containing an azide group. Azido Myristic Acid can be used to identify and characterize post-translationally myristylated proteins with using a simple and robust two-step labeling and detection technique[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-128926

  SPP
  SPP (N-succinimidyl 4-(2-pyridyldithio) pentanoate) is a cleavable disulfide linker, can be used to form cytotoxic compound- linker conjugate[1].

• HY-153370

  DBCO-PEG3-oxyamine-Boc hydrochloride
  DBCO-PEG3-oxyamine-Boc hydrochloride is an ADC linker[1]. DBCO-PEG3-oxyamine-Boc (hydrochloride) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-W071583

  N-Boc-PEG9-alcohol
  N-Boc-PEG9-alcohol is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG9-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-140634

  Ald-CH2-PEG5-azide
  Ald-CH2-PEG5-azide is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Ald-CH2-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-42490

  N3-PEG3-CH2CH2COOH
  N3-PEG3-CH2CH2COOH a PEG-based PROTAC linker can be used in the synthesis of BI-3663 (HY-111546), BI-4216 and BI-0319. Azido-PEG3-acid is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-CH2CH2COOH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-136132A

  MC-VC-PAB-NH2 TFA		99.89%
  MC-VC-PAB-NH2 TFA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-136432A

  Mc-Gly-Gly-Phe-Gly-PAB-OH TFA
  Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA is a cleavable ADC linker used for antibody-drug conjugates (ADCs).

• HY-138535

  Azide-C2-Azide
  Azide-C2-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azide-C2-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-W011541

  SIA Crosslinker
  SIA Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130957

  Amino-PEG6-amido-bis-PEG5-N3
  Amino-PEG6-amido-bis-PEG5-N3 is a cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Amino-PEG6-amido-bis-PEG5-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-126667

  SC-Val-Cit-PAB
  SC-Val-Cit-PAB is a cleavable ADC linker for antibody-drug conjugates (ADCs).

• HY-151782A

  H-(Gly)3-Lys(N3)-OH hydrochloride		99.79%
  H-(Gly)3-Lys(N3)-OH (hydrochloride) is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-126507

  Mal-amido-PEG1-C2-​NHS ester		99.69%
  Mal-amido-PEG1-C2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2]

• HY-126506

  Mal-PEG4-PFP ester
  Mal-PEG4-PFP ester is a nonclaevable ADC linker containing a Maleimide group, 4-unit PEG and a PFP ester.

• HY-133429

  DBCO-PEG3-oxyamine
  DBCO-PEG3-oxyamine is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG3-oxyamine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-141152

  Azido-PEG4-Ala-Ala-Asn(Trt)-PAB
  Azido-PEG4-Ala-Ala-Asn(Trt)-PAB is a cleavable ADC linker.

• HY-12362

  Val-cit-PAB-OH
  Val-cit-PAB-OH is a degradable ADC linker.

• HY-164724

  Bis-PEG30-NHS ester
  Bis-PEG30-NHS ester is a non-claevable 30-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-136037

  Boc-amino-PEG3-SS-acid
  Boc-amino-PEG3-SS-acid is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-136090

  Amino-PEG4-bis-PEG3-N3
  Amino-PEG4-bis-PEG3-N3 is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Amino-PEG4-bis-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-151840

  4-Azidobenzyl alcohol		99.90%
  4-Azidobenzyl alcohol is a click chemistry reagent containing an azide group[1]. 4-Azidobenzyl alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-162941

  SGD-9501-TFA
  GD-9501-TFA is an auristatin S-based ADC linker with effective off-target toxicity characteristics, which can be used for the preparation of antibody-drug conjugates (ADCs)[1].

• HY-151646

  Alkyne-PEG5-SNAP		99.59%
  Alkyne-PEG5-SNAP is a click chemistry reagent containing an alkyne group. Alkyne-PEG5-SNAP can alkyne conjugated benzylguanine (BG), the BG moiety reacts specifically and rapidly with SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality suitable for further conjugation[1]. Alkyne-PEG5-SNAP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-W040244

  Boc-NH-PEG6-CH2CH2COOH
  Boc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC). Boc-NH-PEG6-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-151692

  18-Azido-stearic acid
  18-Azido-stearic acid is a click chemistry reagent containing an azide group. 18-Azido-stearic acid can be used as a hydrophobic bioconjugation linker (using N-Myristoyltransferase) that can be further modified at the azido-position using Click-chemistry[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-Y0755

  N-Boc-4-hydroxy-L-proline methyl ester
  N-Boc-cis-4-hydroxy-L-proline methyl ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-hydroxy-L-proline methyl ester is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2

• HY-132086

  (2-Pyridyldithio)-PEG6 acid
  2-Pyridyldithio-PEG6 acid is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-126502

  Mal-C2-NHS ester		99.30%
  Mal-C2-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-140944

  Biotin-PEG3-SS-azide
  Biotin-PEG3-SS-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Biotin-PEG3-SS-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-151642A

  3-Azido-D-alanine hydrochloride		99.13%
  3-Azido-D-alanine hydrochloride is an azido-modified D-alanine (HY-41700) hydrochloride. 3-Azido-D-alanine hydrochloride can be used in the research of click chemistry labeling[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-151720

  Cy5.5 DBCO
  Cy5.5 DBCO is a click chemistry reagent containing an cycloalkynes group. Cy5.5 DBCO is a linker of Cyanine5.5 fluorophore. DBCO group enables copper free biocompatible click chemistry with fast reaction kinetics and good stability[1].

• HY-151686

  Bz-(Me)Tz-NHS
  Bz-(Me)Tz-NHS is a click chemistry reagent containing an methyltetrazine group. Bz-(Me)Tz-NHS is 3rd generation Click-Linker for Cu-free click conjugation[1].

• HY-130093

  NHPI-PEG3-C2-NHS ester
  NHPI-PEG3-C2-NHS ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-140133

  PC-Biotin-PEG4-PEG3-azide
  PC-Biotin-PEG4-PEG3-azide is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. PC-Biotin-PEG4-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-130376

  Propargyl-PEG8-NHS ester
  Propargyl-PEG8-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG8-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-172291

  Mal-amide-PEG8-Val-Cit-PAB-PNP
  Mal-amide-PEG8-Val-Cit-PAB-PNP is a cleavable ADC linker featuring a maleimide, a PEG spacer, a Val-Cit dipeptide, a PAB. and a PNP carbonate. Maleimide is a thiol-specific covalent linker which is used to label cysteine residues in proteins while the PNP group acts as a highly activated leaving group. Val-Cit linkers are cleaved by cytoplasmic peptidases.

• HY-151773

  Methyltetrazine-PEG12-acid
  Methyltetrazine-PEG12-acid is a click chemistry PEG reagent containing a tetrazine group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1].

• HY-140132

  PC Biotin-PEG3-azide
  PC Biotin-PEG3-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. PC Biotin-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-126960

  Mal-PEG1-acid
  Mal-PEG1-acid is is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG1-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

• HY-129374

  SPDH		98.57%
  SPDH is a cleavable ADC linker used for diagnosis and treatment of cancer or B cell proliferative diseas.

• HY-151702

  (2S)-N3-IsoSer
  (2S)-N3-IsoSer is a click chemistry reagent, a chiral alpha-hydroxypropinoic acid, containing azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-W000423G

  DBCO-amine (GMP)
  DBCO-amine GMP is a GMP grade DBCO-amine (HY-W000423). DBCO-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-amine is a click chemistry reagent, itcontains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-151834

  DBCO-PEG2-DBCO
  DBCO-PEG2-DBCO is a click chemistry reagent containing a DBCO group. DBCO-PEG2-DBCO is a PEG linker containing two terminal DBCO groups. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain allows for increased water solubility. T Reagent grade, for research use only[1].

• HY-126890

  Bis-PEG7-NHS ester
  Bis-PEG7-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG7-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130151

  m-PEG7-CH2CH2COOH
  m-PEG7-CH2CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG7-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

• HY-151741

  Biotin-PEG4-MeTz
  Biotin-PEG4-MeTz is a click chemistry reagent containing a terminal methyltetrazine group that reacts with trans-cyclooctene. Biotin-PEG4-MeTz can be used for the preparation of biotinylated conjugates[1].

• HY-157007

  (S)-TCO-PEG7-NH2
  (S)-TCO-PEG7-NH2 is an ADC linker containing 7 PEG units. (S)-TCO-PEG7-NH2 can use its own TCO group to perform the inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.

• HY-W034918

  Docosanedioic acid
  Docosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Docosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

• HY-141597

  Acid-C3-SSPy
  Acid-C3-SSPy is a cleavable DBA-DM4 linker used in the synthesis of DBA-DM4 (HY-128960), a agent-linker conjugate for ADC[1].

• HY-136056

  Methyltetrazine-PEG4-oxyamine
  Methyltetrazine-PEG4-oxyamine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Methyltetrazine-PEG4-oxyamine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-W002213

  N-Hydroxysulfosuccinimide sodium
  N-Hydroxysulfosuccinimide (sodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-136060

  Mal-PEG2-bis-PEG3-BCN
  Mal-PEG2-bis-PEG3-BCN is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Mal-PEG2-bis-PEG3-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-157006

  (S)-TCO-PEG3-NH2
  (S)-TCO-PEG3-NH2 is an ADC linker containing 3 PEG units. (S)-TCO-PEG3-NH2 can use its own TCO group to perform the inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.

• HY-151864

  DecarboxyBiotin-Alkyne
  DecarboxyBiotin-Alkyne is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1].

• HY-151786

  Fmoc-L-Lys(Pentynoyl-DIM)-OH
  Fmoc-L-Lys(Pentynoyl-DIM)-OH is a click chemistry reagent containing an azide. Fmoc-L-Lys(Pentynoyl-DIM)-OH can be used as a SPPS building block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-151843

  N3-L-Lys(Fmoc)-OH
  N3-L-Lys(Fmoc)-OH is a click chemistry reagent containing an azide group[1]. N3-L-Lys(Fmoc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-151718

  Boc-L-Tyr(PEG(3)-N3)-OH
  Boc-L-Tyr(PEG(3)-N3)-OH is a click chemistry agent containing azide. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-151698

  TCO-NHS Ester (axial)
  TCO-NHS Ester axial is a click chemistry reagent that can be used as a building block in amine reactions. TCO-NHS Ester axial contains TCO groups, which can undergo inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

• HY-W038702

  Boc-Val-Cit-OH
  Boc-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-W190913

  DBCO-PEG4-Val-Cit-PAB-PNP
  DBCO-PEG4-Val-Cit-PAB-PNP is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. PNP can be substituted by amine-containing payload. DBCO enable click chemistry with azide molecules.

• HY-19318G

  Fmoc-Val-Cit-PAB (GMP)
  Fmoc-Val-Cit-PAB GMP is a GMP grade Fmoc-Val-Cit-PAB (HY-19318). Fmoc-Val-Cit-PAB is a cleavable antibody-conjugated active molecule (ADC) commonly used linker.

• HY-W096079

  BCN-endo-PEG4-NHS
  BCN-endo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-endo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand endo-BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

• HY-140129

  NHS-SS-biotin
  NHS-SS-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-133307

  Hydroxy-PEG10-acid		99.59%
  Hydroxy-PEG10-acid (HO-PEG10-CH2CH2COOH) is a PEG-based non-cleavable ADC linker that can be used in the synthesis of Antibody-Drug Conjugates (ADCs)[1].

• HY-130947

  Tetrazine-PEG4-SS-Py
  Tetrazine-PEG4-SS-Py is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetrazine-PEG4-SS-Py is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-151652A

  Boc-L-Cys(Propargyl)-OH (DCHA)
  Boc-L-Cys(Propargyl)-OH (DCHA) is a click chemistry reagent. Boc-L-Cys(Propargyl)-OH (DCHA) can be used for the research of various biochemical[1][2].

• HY-156477

  Me-Tet-PEG8-NHBoc
  Me-Tet-PEG8-NHBoc is an ADC Linker containing 8 PEG units. Me-Tet-PEG8-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

• HY-W044078

  N-Boc-diethanolamine
  N-Boc-diethanolamine is an Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-diethanolamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130386

  Propargyl-PEG6-acid
  Propargyl-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG6-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG6-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-W017882

  (2R,4S)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
  Boc-trans-D-Hyp-OMe is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-trans-D-Hyp-OMe is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

• HY-126504

  Mal-PEG2-NHS ester
  Mal-PEG2-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 2-unit PEG and an NHS ester.

• HY-130969

  Ald-Ph-PEG4-bis-PEG3-N3
  Ald-Ph-PEG4-bis-PEG3-N3 is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Ald-Ph-PEG4-bis-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-156490

  Me-Tet-PEG5-NHS
  Me-Tet-PEG5-NHS is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

• HY-138508

  Biotin-PEG2-methyl ethanethioate
  Biotin-PEG2-methyl ethanethioate is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-136039

  TCO-SS-amine
  TCO-SS-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. TCO-SS-amine is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

• HY-141385

  N-Succinimidyl 3-(Bromoacetamido)propionate
  N-Succinimidyl 3-(Bromoacetamido)propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-Succinimidyl 3-(Bromoacetamido)propionate is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

• HY-128945A

  CL2A TFA		99.49%
  CL2A TFA is a claevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A TFA is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker[1].

• HY-151760A

  (2R,4S)-H-D-Pro(4-N3)-OH hydrochloride
  (2R,4S)-H-D-Pro(4-N3)-OH hydrochloride is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-133409

  4-Methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid
  4-Methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-136318

  β-D-tetraacetylgalactopyranoside-PEG1-N3
  β-D-tetraacetylgalactopyranoside-PEG1-N3 is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. β-D-tetraacetylgalactopyranoside-PEG1-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-151648

  Bis-propargyl-PEG18
  Bis-propargyl-PEG18 is a click chemistry reagent with a propargyl group at each end of the structure.

• HY-W098764

  Allyl (2-aminoethyl)carbamate hydrochloride
  Allyl (2-aminoethyl)carbamate hydrochloride is a cleavable linker.

• HY-150043

  MDTF free acid
  MDTF free acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-W067061

  Hydroxy-PEG2-(CH2)2-Boc
  Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196)[1]. Hydroxy-PEG2-(CH2)2-Boc is also a PROTAC linker that can be used in the synthesis of PROTACs.

• HY-136329

  β-D-glucuronide-pNP-carbonate		99.44%
  β-D-glucuronide-pNP-carbonate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-140136

  PC DBCO-PEG3-biotin
  PC DBCO-PEG3-biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. PC DBCO-PEG3-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-135971

  endo-BCN-PEG4-acid
  endo-BCN-PEG4-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. endo-BCN-PEG4-acid is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-130087

  Bis-PEG3-NHS ester
  Bis-PEG3-NHS ester is a nonclaevable 3-unit PEG linker for antibody-agent-conjugation (ADC).

• HY-136105

  Azido-PEG1-Val-Cit-PABC-PNP
  Azido-PEG1-Val-Cit-PABC-PNP is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG1-Val-Cit-PABC-PNP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-151771

  DACN(Tos,Mal)
  DACN(Tos,Mal) is a click chemistry reagent containing an azide. DACN(Tos,Mal) possess high thermal and chemical stability along with comparable click reactivity[1].

• HY-W000434

  Fmoc-NH-PEG4-CH2CH2COOH
  Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG4-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-115384

  Amino-PEG5-C2-acid
  Amino-PEG5-C2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Amino-PEG5-C2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-156492

  Me-Tet-PEG4-COOH		98.68%
  Me-Tet-PEG4-COOH is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

• HY-135979

  DBCO-SS-PEG4-Biotin
  DBCO-SS-PEG4-Biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-SS-PEG4-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-131990

  MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH		99.22%
  MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-128945

  CL2A		99.49%
  CL2A is a claevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker[1].

• HY-W800620

  NH2-PEG6-Val-Cit-PAB-OH
  NH2-PEG6-Val-Cit-PAB-OH is a cleavable ADC linker featuring a primary amine, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB group. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The primary amine is free to perform a wide variety of reactions such as coupling with carboxylic acids, reductive aminations with ketones or aldehydes, or other more specialized uses such as in SNAr reactions or heterocyclic chemistry. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery via an elimination mechanism within the PAB structure.

• HY-141664

  PPA		99.01%
  PPA is an ADC linker (US20060073528A1). PPA can be used for making antibody-drug conjugate[1].

• HY-140126

  Bis-Tos-(2-hydroxyethyl disulfide)		99.51%
  Bis-Tos-(2-hydroxyethyl disulfide) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-153196

  Tetra-O-acetyl-β-D-galactopyranosyl-Ph-CH2-(4-nitrophenyl)carbonate-Fmoc
  Tetra-O-acetyl-β-D-galactopyranosyl-Ph-CH2-(4-nitrophenyl)carbonate-Fmoc (Example 2.28.6) is an ADC linker that can be used to synthesize antibody-conjugated active molecules (ADCs)[1].

• HY-W019793

  m-PEG8-NHS ester
  m-PEG8-NHS ester is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-130546

  Hydroxy-PEG3-SS-PEG3-alcohol
  Hydroxy-PEG3-SS-PEG3-alcohol is also a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-156300

  Me-Tet-PEG4-NH2
  Me-Tet-PEG4-NH2 is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NH2 can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

• HY-133459

  Mal-PEG1-Val-Cit-OH
  Mal-PEG1-Val-Cit-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-40142

  1-N-Boc-3-hydroxyazetidine
  1-N-Boc-3-hydroxyazetidine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-N-Boc-3-hydroxyazetidine is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs

• HY-130109

  N3-PEG4-C2-NHS ester
  N3-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG4-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-136131

  NH2-PEG4-hydrazone-DBCO
  NH2-PEG4-hydrazone-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. NH2-PEG4-hydrazone-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-44235A

  MC-Gly-Gly-D-Phe		99.38%
  MC-Gly-Gly-D-Phe is a cleavable linker used for sythesis of antibody-drug conjugates (ADC).

• HY-156321

  SCO-PEG7-Maleimide
  SCO-PEG7-Maleimide is a cleavable ADC Linker containing 3 PEG units. SCO-PEG7-Maleimide can be used as a copper-free click chemical reagent for catalyst-free click reactions. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.

• HY-156324

  BCN-exo-PEG8-NHS
  BCN-exo-PEG8-NHS is an ADC Linker containing 8 PEG units. BCN-exo-PEG8-NHS contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.

• HY-125541

  DBCO-NHCO-PEG4-acid
  DBCO-Amide-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-Amide-PEG5-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-NHCO-PEG4-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-164928

  PTAD-PEG8-alkyne
  PTAD-PEG8-alkyne is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-130923

  BCN-PEG1-Val-Cit-PABC-OH
  BCN-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. BCN-PEG1-Val-Cit-PABC-OH is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• HY-148326

  Glu(OtBu)-Val-Cit-PAB-OH
  Glu(OtBu)-Val-Cit-PAB-OH (compound L5-1c) is an non-cleavable ADC linker. Glu(OtBu)-Val-Cit-PAB-OH has been used to synthesis protein-tubulysin conjugates[1].

• HY-151642

  3-Azido-D-alanine
  3-Azido-D-alanine is an azido-modified D-alanine (HY-41700). 3-Azido-D-alanine can be used in the research of click chemistry labeling[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-133504

  Tetrazine-Ph-SS-amine
  Tetrazine-Ph-SS-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetrazine-Ph-SS-amine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

• HY-135975

  MC-Val-Ala-PAB-PNP
  MC-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-120761

  Amino-PEG10-OH
  Amino-PEG10-OH is non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG10-OH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• HY-147325

  bisSP1
  bisSP1 is an antibody agent conjugates linker[1]. bisSP1 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-42360

  SMCC
  SMCC is a protein crosslinker. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses[1].

• HY-130962

  Ald-Ph-amido-PEG23-OPSS
  Ald-Ph-amido-PEG23-OPSS is a cleavable 23 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151735

  N3-L-Dab(Boc)-OH
  N3-L-Dab(Boc)-OH is a click chemistry reagent containing an azide group. N3-L-Dab(Boc)-OH can be used for the research of various biochemical[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-130086

  Bis-​PEG4-​NHS ester
  Bis- PEG4- NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC).

• HY-130954

  Hynic-PEG3-N3
  Hynic-PEG3-N3 is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Hynic-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• HY-151700

  6-Azidohexanoyl-Val-Cit-PAB
  6-Azidohexanoyl-Val-Cit-PAB is a click chemistry reagent that can be used to synthesis vaccine[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-151824

  Boc-L-Phe(4-NH-Poc)-OH
  Boc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent containing an azide group. Used as an orthogonally protected building block in peptide synthesis. Propargyloxycarbonyl, commonly abbreviated as Poc or Pryoc, can either be used as alkyne component for standard Click conjugation or in combination with tetrazine linkers in copper-free Diels-Alder type Click reactions. It also has applications as unusual protecting group for amines, hydroxy functions and as esters. All 3 are stable to neat TFA, but can be cleaved at ambient temperature with Co2(CO)8 in TFA:DCM. Deprotection with other transition metals like palladium have also been reported[1][2]. Boc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• HY-151742

  Norbornene-methyl-NHS
  Norbornene-methyl-NHS is a click chemistry reagent containing a TCO group. Dienophile for conjugation via Diels-Alder-reaction, i.e. copper-free click reaction with tetrazines[1].

• HY-151785

  H-L-Dbu(N3)-OH
  H-L-Dbu(N3)-OH is a click chemistry reagent containing an azide group[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• HY-135928

  Biotin-C2-S-S-pyridine
  Biotin-C2-S-S-pyridine is a cleavable ADC linker. Biotin-C2-S-S-pyridine can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-114430

  Fmoc-Phe-Lys(Boc)-PAB-PNP		98.67%
  Fmoc-Phe-Lys(Boc)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

• HY-138369

  Methylamino-PEG3-benzyl
  Methylamino-PEG3-benzyl is an amino PEG linker.

• HY-W071007

  NO2-SPDMV
  NO2-SPDMV is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-139856

  Mal-Ala-Ala-PAB-PNP
  Mal-Ala-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-W021787

  NH2-PEG4-CH2CH2COOH
  NH2-PEG4-CH2CH2COOH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). NH2-PEG4-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

• HY-151821

  Sulfo DBCO-PEG3-acid
  Sulfo DBCO-PEG3-acid is a click chemistry reagent containing an azide group. Sulfo DBCO-PEG3-acid is an analog of DBCO-Acid with PEG linker and a DBCO group. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain and sulfo group increase water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research use only[1].

• HY-156493

  Me-Tet-PEG5-COOH
  Me-Tet-PEG5-COOH is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

• HY-130824

  Bis-PEG10-NHS ester
  Bis-PEG10-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG10-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-117031

  m-PEG8-MS
  m-PEG8-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG8-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151688

  6-O-Propynyl-2'-deoxyguanosine		99.51%
  6-O-Propynyl-2'-deoxyguanosine is a click chemistry reagent containing an alkyne group. 6-O-Propynyl-2'-deoxyguanosine can be used for the research of various biochemical[1].

• HY-79129

  Fmoc-D-Trp(Boc)-OH
  Fmoc-D-Trp(Boc)-OH is a cleavable ADC linker that used in the synthesis of antibody-drug conjugates (ADCs).

• HY-44980

  Fmoc-Gly-NH-CH2-acetyloxy
  Fmoc-Gly-NH-CH2-acetyloxy is a cleavable linker that can be used to synthesize antiboy-drug Conjugates (ADCs).

• HY-126519

  PDdEC-NB
  PDdEC-NB is a disulfide cleavable linker used for the antibody-drug conjugate (ADC).

• HY-130410

  Bis-PEG6-NHS ester
  Bis-PEG6-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• HY-151724

  N3-Pen-Dde
  N3-Pen-Dde is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.