1. PI3K/Akt/mTOR
  2. Akt


Akt Related Products (44):

Cat. No. Product Name Effect Purity
  • HY-10256
    SB 203580 Inhibitor 99.54%
    SB 203580 is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM, also blocks PKB phosphorylation with IC50 of 3-5 μM.
  • HY-10358
    MK 2206 dihydrochloride Inhibitor 99.27%
    MK 2206 is an orally active allosteric Akt inhibitor with IC50 of 5 nM/12 nM/65 nM for Akt1/Akt2/Akt3, respectively.
  • HY-18749
    SC79 Inhibitor >98.0%
    SC79 is a brain-penetrable Akt phosphorylation activator and an inhibitor of Akt-PH domain translocation.
  • HY-15431
    AZD5363 Inhibitor
    AZD5363 is a potent pan-AKT kinase inhibitor with IC50 of 3, 7 and 7 nM for Akt1,Akt2 and Akt3, respectively.
  • HY-10256A
    SB 203580 hydrochloride Inhibitor 99.71%
    SB 203580 hydrochloride is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM, also blocks PKB phosphorylation with IC50 of 3-5 μM.
  • HY-U00458
    K-80003 Inhibitor
    K-80003 is a potent inhibitor of tRXRα-dependent Akt activation and cancer cell growth.
  • HY-N1505
    Loureirin A Inhibitor 99.76%
    Loureirin A is a flavonoid extracted from Dragon׳s Blood, can inhibit Akt phosphorylation, and has antiplatelet activity.
  • HY-15186
    GDC-0068 Inhibitor 98.89%
    GDC-0068 is a highly selective pan-Akt inhibitor targeting Akt1/Akt2/Akt3 with IC50 of 5/18/8 nM, 620-fold selectivity over PKA.
  • HY-10249
    GSK-690693 Inhibitor
    GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2/13/9 nM in cell-free assays, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. 
  • HY-10355
    AKT inhibitor VIII Inhibitor 98.02%
    AKT inhibitor VIII is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity with IC50s of 58 nM, 210 nM, and 2119 nM, respectively.
  • HY-15457
    Triciribine Inhibitor 99.20%
    Triciribine is a DNA synthesis inhibitor, also inhibits Akt and HIV-1/2 with IC50 of 130 nM, and 0.02-0.46 μM, respectively.
  • HY-13254
    A-674563 Inhibitor 99.86%
    A-674563 is a potent selective Akt1 inhibitor with Ki of 11 nM.
  • HY-N0003
    Honokiol Inhibitor 99.71%
    Honokiol is a hydroxylated biphenyl compound, which inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.
  • HY-10425
    A-443654 Inhibitor 99.90%
    A-443654 is a potent small-molecule inhibitor of all three Akt serine/threonine kinases, with Ki of 160 pM for Akt1.
  • HY-13685
    Miltefosine Inhibitor >98.0%
    Miltefosine is a PI3K/Akt inhibitor, dramatically reduces HIV-1 production from long-living virus-infected macrophages.
  • HY-15727
    Afuresertib Inhibitor 98.95%
    Afuresertib is an orally available, ATP-competitive, pan-AKT inhibitor with Ki of 0.08, 2 and 2.6 nM against AKT1, AKT2 and AKT3, respectively.
  • HY-15615A
    TIC10 Inhibitor 99.68%
    TIC10 is a potent, orally active, and stable TRAIL inducer, also inhibits Akt and ERK activity.
  • HY-50909
    Perifosine Inhibitor >98.00%
    Perifosine is an oral Akt inhibitor. All cells are sensitive to the antiproliferative properties of Perifosine with an IC50 of ~0.6-8.9 μM.
  • HY-15965
    GSK2141795 Inhibitor 99.85%
    GSK2141795 is a potent and selective pan-Akt inhibitor with IC50 values of 180/328/38 nM for Akt1/Akt2/Akt3, respectively.
  • HY-13425
    Deguelin Inhibitor 98.64%
    Deguelin is a natural product isolated from plants in the Mundulea sericea family, and acts as an AKT inhibitor.