2. GPCR/G Protein
  3. Cholecystokinin Receptor

Cholecystokinin Receptor

Cholecystokinin Receptor

Related Products

PDF 0.3 MB

Cholecystokinin (CCK) is a neuropeptide that affects growth rate in chickens by regulating appetite. CCK peptides exert their function by binding to two identified receptors, CCKAR and CCKBR in the GI tract and the brain, respectively, as well as in other organs. In mammals, CCK/CCKAR interactions affect a number of immunological parameters, including regulation of lymphocytes and functioning of monocytes.

CCK, also known as pancreozymin, is synthesized and secreted by enteroendocrine cells in the duodenum. The main function of CCK is to cause the release of digestive enzymes and bile from the pancreas and gallbladder, respectively. It also induces drug tolerance to opioids like morphine and heroin. Cholecystokinin (CCK) has strong bioactivity in the regulation of a number of cell activities.

Cholecystokinin Receptor Related Products (13):

Cat. No. Product Name Effect Purity
  • HY-A0190
    Ceruletide Agonist 99.96%
    Ceruletide, a biologically active decapeptide isolated from the skin of the Australian frog Hyla caerulea, is a potent cholecystokinetic agent, and acts as a cholecystokinin receptor agonist.
  • HY-17617
    Nastorazepide Antagonist 99.78%
    Nastorazepide (Z-360) is a selective, orally available, 1,5-benzodiazepine-derivative gastrin/cholecystokinin 2 (CCK-2) receptor antagonist with potential antineoplastic activity.
  • HY-B1330
    Proglumide Antagonist 99.74%
    Proglumide is a known cholecystokinin (CCK) antagonist.
  • HY-P1097
    Gastrin-1, human 98.39%
    Gastrin-1, human is the endogenous peptide produced in the stomach, and increases gastric acid secretion via cholecystokinin 2 (CCK2) receptor.
  • HY-B2154
    Loxiglumide Antagonist >98.0%
    Loxiglumide is a cholecystokinin (CCK-1) receptor antagonist.
  • HY-14850
    Sograzepide Antagonist
    Sograzepide (Netazepide;YF476) is a gastrin/cholecystokinin 2 receptor (CCK2) antagonist.
  • HY-11077
    SR 146131 Agonist
    SR 146131 is a potent, orally available, and selective nonpeptide (cholecystokinin 1) receptor agonist.
  • HY-11076
    GI 181771 Agonist
    GI 181771 is a cholecystokinin 1 receptor agonist investigated for the treatment of obesity.
  • HY-P1593
    Mini Gastrin I, human
    Mini Gastrin I, human is a shorter version of human gastrin 1, consists of amino acids 5-17 of the parent peptide, and binds with the CCK2i4svR.
  • HY-U00062
    Tarazepide Antagonist
    Tarazepide is a potent and specific CCK-A receptor antagonist.
  • HY-U00387
    CCK-A receptor inhibitor 1 Inhibitor
    CCK-A receptor inhibitor 1 is a cholecystokinin A (CCK-A) receptor inhibitor with a binging IC50 of 340 nM.
  • HY-U00375
    Gastrin/CCK antagonist 1 Antagonist
    Gastrin/CCK antagonist 1 is an antagonist of gastrin/CCK, used for the research of gastrointestinal disorders.
  • HY-U00360
    CCK-B Receptor Antagonist 1 Antagonist
    CCK-B Receptor Antagonist 1 is an antagonist of cholecystokinin B (CCK-B) receptor, and has the potential of reducing the secretion of gastric acid.