1. Metabolic Enzyme/Protease
  2. Ser/Thr Protease

Ser/Thr Protease

Serine proteases are enzymes that cleave peptide bonds in proteins, in which serine serves as the nucleophilic amino acidat the active site. They are found ubiquitously in both eukaryotes and prokaryotes. Serine proteases fall into two broad categories based on their structure: chymotrypsin-like or subtilisin-like. In humans, serine proteases are responsible for co-ordinating various physiological functions, including digestion, immune response, blood coagulation and reproduction. Threnonine proteases are a family of proteolytic enzymes harbouring a threonine (Thr) residue within the active site. The prototype members of this class of enzymes are the catalytic subunits of the proteasome, however the acyltransferases convergently evolved the same active site geometry andmechanism.

Ser/Thr Protease Related Products (5):

Cat. No. Product Name Effect Purity
  • HY-B0190A
    Nafamostat mesylate Inhibitor 98.39%
    Nafamostat mesylate, a synthetic serine protease inhibitor, is an anticoagulant.
  • HY-101214
    UK-371804 Inhibitor >98.0%
    UK-371804 is a urokinase-type plasminogen activator (uPA) inhibitor with a Ki of 10 nM.
  • HY-B0190
    Nafamostat Inhibitor
    Nafamostat is a broad spectrum serine protease inhibitor, kallikrein inhibitor, and inhibits blood coagulation; is also a possible complement inhibitor.
  • HY-B0190B
    Nafamostat hydrochloride Inhibitor
    Nafamostat hydrochloride, a synthetic serine protease inhibitor, is an anticoagulant.
  • HY-U00346
    DPP-IV-IN-1 Inhibitor
    DPP-IV-IN-1 is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV), a highly specific serine protease, with an IC50 of 4.6 nM.