1. Immunology/Inflammation
  2. ALCAM/CD166


ALCAM (CD166), a cell surface glycoprotein, is a cell adhesion molecule of the immunoglobulin superfamily. ALCAM is expressed by various cell types, such as leukocytes and endothelial cells (ECs). ALCAM can bind to the T cell-expressed scavenger receptor CD6, endothelial L1CAM, and galectin-8. ALCAM regulates diverse pathophysiological processes, including T cell activation, leukocyte trafficking, and angiogenesis. ALCAM is a prognostic marker of cancers. ALCAM promotes tumor growth by controlling cell proliferation, adhesion, migration and invasion[1][2].

ALCAM/CD166 Related Products (1):

Cat. No. Product Name Effect Purity
  • HY-P99788
    Praluzatamab Inhibitor
    Praluzatamab is a monoclonal antibody targeting the activated leukocyte cell adhesion molecule (ALCAM/CD116). Praluzatamab can be used to synthesize Praluzatamab ravtansine (antibody-drug conjugates). Praluzatamab can be used for research of cancers[1][2].