1. Others
  2. Drug Derivative

Drug Derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1291):

Cat. No. Product Name Effect Purity
  • HY-42682
    D(+)-Galactosamine hydrochloride
    D(+)-Galactosamine (D-Galactosamine) hydrochloride, which is an established experimental toxin, primarily causes liver injury by the generation of free radicals and depletion of UTP nucleotides. D(+)-Galactosamine hydrochloride intoxication also induces renal dysfunction thus, renal failure is often associated with the end-stage of the liver damage. Lipopolysaccharide/D(+)-Galactosamine-induced acute liver injury is a known animal model of fulminant hepatic failure[1][2].
  • HY-W011500
    TCEP hydrochloride
    TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that is more stable and produces a faster S-S reductive reaction than other chemical reductants. TCEP hydrochloride is a trialkylphosphine, selectively reduces protein disuldes without altering the properties or interacting with thiol-directed agents in the reaction mixture. TCEP hydrochloride is also a commonly used reducing agent in the DNA/AuNP chemistry[1][2][3][4].
  • HY-I0960
    Uracil
    Uracil is a pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA. Uracil is a frequently occurring DNA base damage that results from the spontaneous or chemically induced deamination of cytosine and is mutagenic at the level of replication. Uracil could potentially alter transcriptional fidelity, resulting in production of mutant proteins[1][2][3][4][5].
  • HY-148335
    IRG1-IN-1 99.82%
    IRG1-IN-1 is an itaconic acid derivative. IRG1-IN-1 can inhibit immune-responsive gene 1 (IRG1) activity. IRG1-IN-1 can be used for the research of cancer, inflammation and autoimmune diseases[1].
  • HY-B0717
    Tocofersolan
    Tocofersolan is synthetic polyethylene glycol derivative of α-tocopherol. Tocofersolan is an orally active and water-soluble analog of vitamin E. Tocofersolan can reduce neurobehavioral deficits in zebrafish embryos exposed to moderate and high concentrations of BaP during early development. Tocofersolan shows antioxidant activity. Tocofersolan can be used to provide an orally bioavailable source of vitamin E[1][2][3].
  • HY-N13921
    Aphidicolin-3,18-orthoacetate
    Aphidicolin-3,18-orthoacetate is an aphidicolin derivative that inhibits the root growth of rice seedlings[1].
  • HY-N15335
    Anti-inflammatory agent 98
    Anti-inflammatory agent 98 (Compound 8) is a potent NO production inhibitor with an IC50 value of 14.79 μM. Anti-inflammatory agent 98 is a benzofuran with anti-inflammatory activities, which is found in the roots of Paeonia lactiflora Pall[1].
  • HY-N15334
    Tricrozarin A
    Tricrozarin A is a naphthazarin derivative, which is found in fresh bulbs of Tritonia crocosmaeflora. Tricrozarin A exhibits antimicrobial activity against gram-positive bacteria, fungi, and yeast[1].
  • HY-118687
    4-Bromoethcathinone hydrochloride
    4-Bromoethcathinone hydrochloride is structurally categorized as a cathinone.
  • HY-117906
    GV196771
    GV196771 is an active compound.
  • HY-117558
    (Rac)-L-826141
    (Rac)-L-826141 is an active compound.
  • HY-76665
    Anticancer agent 209
    Anticancer agent 209 (compound 1) is an anticancer agent. Anticancer agent 209 exhibits cytotoxic activity against colon cancer in vitro[1].
  • HY-168416
    4-EA-NBOMe hydrochloride
    4-EA-NBOMe hydrochloride is structurally categorized as a phenethylamine[1].
  • HY-145614
    Sucistil
    Sucistil is an active compound. hemoglobin sucistil (bovine) is an oxygen carrier[1].
  • HY-N0572
    9-Hydroxycamptothecin 98.13%
    9-Hydroxycamptothecin (9-Hydroxycamptothecine; compound 23c) is a Camptothecin (HY-16560) derivative with anticancer activities[1].
  • HY-113713
    CH-38083
    CH-38083 is an active compound.
  • HY-W587559
    Fenthion sulfone
    Fenthion sulfone is an active compound.
  • HY-135266
    N-Ethyl Tadalafil
    N-Ethyl Tadalafil is an active compound.
  • HY-B0322B
    Sulfamethoxazole 1000 µg/mL in methanol
    Sulfamethoxazole 1000 μg/mL in methanol (Ro 4-2130 1000 μg/mL in methanol) is an active compound.
  • HY-168364
    1(R),2(S)-epoxy Cannabidiol
    1(R),2(S)-epoxy Cannabidiol (Compound 2a) is a structural analogue of phytocannabinoidsphytocannabinoids. 1(R),2(S)-epoxy Cannabidiol exhibits potent inhibitory activity against Wnt/β-catenin pathway. 1(R),2(S)-epoxy Cannabidiol is promising for research of neuroprotective agents[1].