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  3. Drug Isomer

Drug Isomer

Drug isomers are compounds with the same molecular formula but different atomic arrangements or spatial configurations. They are divided into structural isomers and stereoisomers, and have different biological activities, safety and metabolic characteristics. Drug isomers can be used as drug improvement groups or drug efficacy control groups. For example, Carvedilol has higher bioavailability and better safety than (R)-Carvedilol.

Drug Isomer Related Products (174):

Cat. No. Product Name Effect Purity
  • HY-A0132
    N-Acetyl-D-glucosamine
    N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose), the D isomer of N-acetylglucosamine, is an orally active monosaccharide derivative of glucose with anti-tumor and anti-inflammation properties. N-Acetyl-D-Glucosamine is also a bacterial metabolite, which is found in Escherichia coli. N-Acetyl-D-Glucosamine can induce yeast-mycelial conversion in Candida albicans. N-Acetyl-D-Glucosamine also enhances healing of cartilaginous injuries in rabbits[1][2][3].
  • HY-B0927
    Hydrastine
    Hydrastine is a natural alkaloid found in Hydrastis canadensis and other plants of the Ranunculaceae family.
  • HY-126076
    VPC-80051 racemate 98.99%
    VPC-80051 racemate is a racemate of VPC-80051. VPC-80051 is a prototype inhibitor of the hnRNP A1 splicing factor[1].
  • HY-W011688
    Methyl palmitoleate
    Methyl palmitoleate ((Z)-Methyl hexadec-9-enoate), a fatty acid methyl ester, is an analogue of Palmitoleate with cytoprotective and growth-promoting properties[1].
  • HY-113381A
    (R)-2-Hydroxybutanoic acid
    (R)-2-Hydroxybutanoic acid is the isomer of 2-Hydroxybutyric acid (HY-113381), and can be used as an experimental control. 2-Hydroxybutyric acid (α-Hydroxybutyric acid ) is converted from 2-Aminobutyric acid, with 2-oxobutyric acid as an intermediate metabolite[1].
  • HY-W674436
    (S)-Thalidomide-4-OH
    (S)-Thalidomide-4-OH is the S-isomer of Thalidomide-4-OH (HY-103596). Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs[1].
  • HY-137862A
    (Rac)-1-Oleoyl lysophosphatidic acid
    (Rac)-1-Oleoyl lysophosphatidic acid is an isomer of 1-Oleoyl lysophosphatidic acid sodium (HY-107614). 1-Oleoyl lysophosphatidic acid sodium is a bioactive lipid that can activate the LPA receptors [1].
  • HY-W007880
    (R)-D2PM
    (R)-D2PM is an isomer of the psychoactive substance D2PM and a pyrrolidine analog[1].
  • HY-18299B
    (S)-Purvalanol B
    (S)-Purvalanol B is the S enantiomer of Purvalanol B. Purvalanol B is a cyclin-dependent kinase inhibitor.
  • HY-I0726
    Enantiomer of Sofosbuvir 99.68%
    Enantiomer of Sofosbuvir is an enantiomer of Sofosbuvir, a prescription medicine for the treatment of patients with chronic hepatitis C. There is no biological activity report on enantiomer of Sofosbuvir until now.
  • HY-W012732R
    Isoquinoline (Standard)
    Isoquinoline (Standard) is the analytical standard of Isoquinoline. This product is intended for research and analytical applications. Isoquinoline is an analog of pyridine. Isoquinoline structural-based alkaloids, such as tropoloisoquinoline, phthalideisoquinoline, and naphthylisoquinoline has anti-cancer activities[1].
  • HY-139421
    (Z)-16-(Ethylcarbamoylamino)hexadec-11-enoic acid
    (Z)-16-(Ethylcarbamoylamino)hexadec-11-enoic acid (Compound 21) is a vasorelaxant (EC50=5.7 μM) that can be used in cardiovascular disease research[1].
  • HY-145572B
    (S)-Imlunestrant tosylate Control 98.74%
    (S)-Imlunestrant ((S)-LY-3484356) tosylate is an (S)-enantiomer of Imlunestrant (HY-145572). (S)-Imlunestrant tosylate can be used in research of cancer[1].
  • HY-15584C
    (R)-Taltobulin
    (R)-Taltobulin ((R)-HTI-286) can be used as a reference substance[1].
  • HY-W202854
    Methiopropamine 3’-thiophene isomer hydrochloride Control
    Methiopropamine 3’-thiophene isomer is an isomer of Methiopropamine that has the sulfur atom of the thiophene group at the 3 position.
  • HY-155295
    Z-CITCO
    Z-CITCO is the cis isomer of CITCO (HY-103244). Z-CITCO is an agonist of constitutive androstane receptor (CAR) with an EC50 value of 3.9 µM[1].
  • HY-16560B
    (R)-Camptothecin
    (R)-Camptothecin is an enantiomer of Camptothecin (CPT), is inactive as an inhibitor of the DNA religation reaction and consequently do not poison Top1[1].
  • HY-113381B
    (R)-2-Hydroxybutanoic acid sodium
    (R)-2-Hydroxybutanoic acid ((R)-α-Hydroxybutyric acid) sodium is the R-isomer of 2-Hydroxybutyric acid (HY-113381), and can be used as an experimental control. 2-Hydroxybutyric acid is converted from 2-Aminobutyric acid, with 2-oxobutyric acid as an intermediate metabolite[1].
  • HY-160144S2
    (rac)-Lomedeucitinib 98.11%
    (rac)-Lomedeucitinib ((rac)-BMS-986322) is the racemate of Lomedeucitinib. Lomedeucitinib (BMS-986322) is a tyrosine protein kinase (TYK2) inhibitor. Lomedeucitinib has anti-inflammatory activity and significant inhibitory effect on IFNα (IC50=0.047 μM) production downstream of IL-12/TYK2. Lomedeucitinib is indicated for the study of plaque psoriasis and pruritus[1][2][3].
  • HY-13250B
    Silvestrol aglycone (enantiomer) 99.10%
    Silvestrol aglycone enantiomer is a cyclopenta benzofuran core phenol[1].