1. Screening Libraries
  2. Cell Cycle/DNA Damage Compound Library

Cell Cycle/DNA Damage Compound Library

(466 compounds) Cat. No.: HY-L004
Library Contents: XLSX PDF

A unique collection of 466 Cell Cycle/DNA Damage related compounds for high throughput screening (HTS) and high content screening (HCS).

Size (Pre-dissolved DMSO or Solid) Price Stock
30 μL/well (10 mM solution) Get quote In-stock
50 μL/well (10 mM solution) Get quote In-stock
100 μL/well (10 mM solution) Get quote In-stock
250 μL/well (10 mM solution) Get quote In-stock

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  • Description

  • Product Details

  • Composition

  • Contents

  • Documentation

Description
& Advantages

•   A unique collection of 466 Cell Cycle/DNA Damage related compounds for high throughput screening (HTS) and high content screening (HCS).

•   Targets such as CDK, ROCK, Aurora Kinase, ATM/ATR, DNA-PK, DNA/RNA Synthesis, etc.

•   A useful tool to study the mechanism of cell cycle regulators that are critical to normal development and the development of cancer, cardiovascular, inflammatory, and neurodegenerative diseases.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.

•   Structurally diverse, medicinally active, and cell permeable.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   NMR and HPLC validated to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

Product Details
Formulation:
A collection of 466 Cell Cycle/DNA Damage related compounds supplied as pre-dissolved DMSO solutions or Solid
Container:
96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice
Composition

Contents of Cell Cycle/DNA Damage Compound Library

Plate layout: HY-L004-1

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Flavopiridol Flavopiridol (Hydrochloride) SNS-032 KNK437 TA-01 AZD-5438 MS049 NKL 22 Y-27632 Triapine Empty
b Empty AZD1152-HQPA AZD1152 ZM-447439 Veliparib (dihydrochloride) Tozasertib Olaparib MLN8054 17-AAG BIIB021 NVP-AUY922 Empty
c Empty Vorinostat CUDC-101 Panobinostat Belinostat GSK-923295 D4476 Fasudil (Hydrochloride) PHA-848125 Pralatrexate Dinaciclib Empty
d Empty Lexibulin Tasquinimod Betulinic acid BIO Y-27632 (dihydrochloride) Valproic acid (sodium salt) 5-Azacytidine A-966492 Rucaparib (phosphate) MK-4827 Empty
e Empty MK-4827 (tosylate) BMS-687453 CCT 137690 Pemetrexed (disodium) GW 501516 VER-155008 NVP-BEP800 Alisertib Amonafide ENMD-2076 (Tartrate) Empty
f Empty ENMD-2076 PCI-24781 AZD-7762 MK-1775 GSK429286A PHA-793887 CP-466722 GW843682X KU-57788 SNS-314 Empty
g Empty BSI-201 KU-55933 INO-1001 Alvespimycin (hydrochloride) Rigosertib (sodium) HMN-214 CCT129202 Hesperadin KU-60019 SB-743921 Empty
h Empty Poloxin Volasertib Entinostat Mocetinostat TAK-901 Kenpaullone GSK0660 G007-LK ISRIB (trans-isomer) LY3023414 Empty

Plate layout: HY-L004-2

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Ro-3306 ON123300 IC261 CB-5083 AZ6102 PF-3758309 CDK-IN-2 Daun02 Daunorubicin (Hydrochloride) Celastrol Empty
b Empty T0070907 CDK9-IN-1 MK-5108 AMG 900 TAME Thiazovivin CHIR-124 WP1130 Droxinostat ABT-751 Empty
c Empty Tubastatin A (Hydrochloride) Tubastatin-A PIK-75 PYR-41 PYZD-4409 Mps1-IN-1 SR-3677 Mitomycin C Pracinostat Tenovin-1 Empty
d Empty RITA PHA-767491 (hydrochloride) Debio 0932 Mitoxantrone (dihydrochloride) M344 Sirtinol Nocodazole AZD-2461 Gemcitabine (elaidate) Uramustine Empty
e Empty Amsacrine β-Lapachone Carmustine Cytarabine Dacinostat Epirubicin (hydrochloride) Estramustine (phosphate sodium) Etoposide Folinic acid (Calcium) Levoleucovorin (Calcium) Empty
f Empty Lomustine 6-Mercaptopurine PJ34 (hydrochloride) Nelarabine SN-38 Pirarubicin Pirarubicin (Hydrochloride) Streptozocin TAS-103 (dihydrochloride) Teniposide Empty
g Empty 6-Thioguanine Topotecan (Hydrochloride) Vinblastine (sulfate) Pemetrexed (disodium hemipenta hydrate) (1:2:2.5) PR-619 MK-8745 GSK2656157 P 22077 VE-822 RGFP966 Empty
h Empty Hydroxyfasudil (hydrochloride) GW0742 BML-277 JW 55 b-AP15 TBB AT13387 UPF 1069 Methotrexate PF-03814735 Empty

Plate layout: HY-L004-3

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Rosiglitazone (maleate) Pioglitazone (hydrochloride) AZ3146 Reversine CCT241533 (hydrochloride) LY2603618 VE-821 Palifosfamide Cevipabulin Doxorubicin (hydrochloride) Empty
b Empty SRT 1720 (Hydrochloride) XAV-939 NG 52 SBE13 (Hydrochloride) TAK-960 Ro3280 SB1317 Pyridostatin (hydrochloride) ARRY-520 ARRY-520 (R enantiomer) Empty
c Empty NVP-HSP990 Ganetespib CHR-6494 Geldanamycin NVP-LCQ195 XL413 (hydrochloride) SRT 2104 BMS-265246 Epothilone D RI-1 Empty
d Empty TG003 CVT-313 EX-527 Triciribine Cabazitaxel TTP 22 D-64131 Scriptaid PF-670462 CGK733 Empty
e Empty ETP-46464 DMAT FRAX486 Podophyllotoxin AZ20 GSK3787 Sodium phenylbutyrate GW1929 IPA-3 P005091 Empty
f Empty LH846 NMS-873 NU 7026 FH535 Ansamitocin P-3 XL228 RKI-1447 SJB2-043 LEE011 LEE011 (succinate) Empty
g Empty NMS-1286937 CW-069 Inauhzin LDC000067 AMG 925 5-BrdU DBeQ 4SC-202 (free base) ACY-1215 Balaglitazone Empty
h Empty ELR510444 Forodesine (hydrochloride) Genz-644282 INNO-206 APTO-253 LY2835219 Miriplatin RG2833 Treosulfan Campathecin Empty

Plate layout: HY-L004-4

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Irinotecan (hydrochloride) Irinotecan (hydrochloride trihydrate) Colchicine GW9662 Remodelin (hydrobromide) Elafibranor MC1568 CC-115 Wy-14643 Gemcitabine Empty
b Empty Epothilone B BIBR 1532 Fenofibrate Temozolomide Oxaliplatin Idarubicin (hydrochloride) Levomefolate (calcium) Rosiglitazone Carboplatin Cisplatin Empty
c Empty Tegafur Vinblastine Ifosfamide Cyclophosphamide 4'-Demethylepipodophyllotoxin Fosbretabulin (disodium) ML-323 Thio-TEPA Melphalan LFM-A13 Empty
d Empty Pyrimethamine GSK2606414 Purvalanol B Purvalanol A BMS-3 BMS-5 TMP269 SU9516 LDN-57444 TZ9 Empty
e Empty PU-WS13 Centrinone Centrinone-B BRD73954 BG45 CCT245737 UF010 LMK-235 NU2058 AZD6738 Empty
f Empty Compound 401 Pimelic Diphenylamide 106 BML-210 MN-64 Pimelic Diphenylamide 106 (analog) Maytansinol DG172 (dihydrochloride) JW74 ML240 ML241 (hydrochloride) Empty
g Empty PRT4165 Dimethylenastron K858 L-165041 Roscovitine AT9283 BI 2536 Ispinesib Palbociclib Palbociclib (hydrochloride) Empty
h Empty CX-4945 CX-4945 (sodium salt) GSK461364 CI-994 Troglitazone AT7519 (trifluoroacetate) AT7519 (Hydrochloride) GSK-1070916 Aurora A inhibitor I THZ1 Empty

Plate layout: HY-L004-5

1 2 3 4 5 6 7 8 9 10 11 12
a Empty THZ1 (Hydrochloride) Clofarabine Trifluorothymidine Tipiracil (hydrochloride) Palbociclib (isethionate) Gemcitabine (Hydrochloride) Docetaxel Paclitaxel Capecitabine Doxifluridine Empty
b Empty Fludarabine (phosphate) Dacarbazine Folinic acid (calcium salt pentahydrate) Floxuridine Adenine Cytidine Altretamine Carmofur Ellagic acid Adenosine Empty
c Empty Busulfan Gemfibrozil Vidarabine Clofibrate Sodium Butyrate Trimethoprim Flumequine Triclabendazole Vinflunine (Tartrate) Bezafibrate Empty
d Empty Ciprofibrate Fotemustine Teprenone Parthenolide Orotic acid Vincristine (sulfate) Empty Empty Empty Empty Empty
e Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
f Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
g Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
h Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
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