2. Screening Libraries
  3. Antihypertensive Compound Library

Antihypertensive Compound Library

(634) Cat. No.: HY-L145
Library Contents: XLSX PDF

The majority of hypertensive patients have primary (or essential) hypertension, that is, hypertension in which secondary causes are not present. Management aims to control arterial pressure, prevent end-organ damage (cerebrovascular, cardiovascular, and renal), and reduce the risk of premature death.

Antihypertensive drugs may be divided into two broad groups, the first group being those which directly or indirectly block the renin–angiotensin system (RAS), for example, ACEIs, angiotensin receptor antagonists (ARAs), direct renin inhibitors (DRIs), and to a lesser extent β-blockers. The second group of drugs works by increasing water and sodium excretion, thereby reducing intravascular volume, or by causing vasodilatation through non-RAS pathways, for example, diuretics and calcium channel blockers (CCBs).

MCE offers a unique collection of 634 compounds with identified and potential antihypertensive activity. MCE Antihypertensive Compound Library is critical for antihypertensive drug discovery and development.

Size (Pre-dissolved DMSO or Solid) Price Stock
30 μL/well (10 mM solution) Get quote In-stock
50 μL/well (10 mM solution) Get quote In-stock
100 μL/well (10 mM solution) Get quote In-stock
250 μL/well (10 mM solution) Get quote In-stock
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Description
& Advantages

•    A unique collection of 634 antihypertensive inhibitors for high throughput screening (HTS) and high content screening (HCS).

•    A useful tool for the study of critical for drug discovery and development.

•    Target diverse, medicinally active and cell permeable.

•    Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•    More detailed compound information with structure, IC50, and other chemical & biological data.

•    High purity and quality validated by NMR and LC/MS.

Product Details
Formulation:
A collection of 634 antihypertensive inhibitors supplied as pre-dissolved Solutions or Solid
Container:
96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice
Composition
Contents of Antihypertensive Compound Library
Documentation

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Antihypertensive Compound Library
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HY-L145
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