Glycomimetic Library

•   A specially synthesized set of 2 compounds able to mimic glycosides and their interaction with proteins.

•   Privileged core fragments and side chain functionalities: cyclic amino alcohols, cyclic glycols; O,N-containing aliphatic rings; polyalcohols.

•   We suppose the library application would identify new attractive chemotypes which correspond to drug-/lead-like criteria and on the other hand participate in key interactions similar to glycoside binding in the active site of the targets.

•   Nature-likeness scoring algorithm: Taverna 2.5 workbench, similarity to available NP databases.

•   MedChem structural filters, removal of common and trivial chemotypes: PAINS, REOS, Elli Lily rules and strict Enamine filters.

•   Structurally diverse.

•   NMR and HPLC validated to ensure high purity and quality.

•   All compounds can be readily followed with analogues either from stock or from new syntheses.

•   Databases and compounds are provided by Enamine.

Formulation:

来源于 Enamine, 能够模拟糖苷及其与蛋白质的相互作用的化合物集合。

Container:

Storage:

-80°C

Shipping: