2. Screening Libraries
  3. Sodium Ion Channel Library

Sodium Ion Channel Library

(5,440) Cat. No.: HY-L0099V
Library Contents: XLSX PDF

Sodium Ion Channel Library contains about 5,440 compounds, and designed for discovery of new Nav1.7 channel blockers. Sodium voltage-gated ion channel is considered to be an important component in nociception. Therefore, selective Nav1.7 channel blockers are considered as important novel analgesics. The Sodium Ion Channel Library is rich in compounds bearing saturated backbones that can be often seen in structures of other ion-channel blockers.

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Description
& Advantages

•   Compound rich in saturated skeleton that can be often seen in structures of other ion-channel blockers.

•   All compounds meet requirements of Ro5, and 67% compounds are considered lead-like.

•   The most abundant are relatively flat aromatic cores.

•   Presence of highly polar backbone fragments/moieties (e.g. CONH2, SO2NHR, polar heterocycles, etc).

•   Databases and compounds are provided by Enamine.
Product Details
Formulation:
来源于Enamine，包含5,440 个化合物，旨在发现新的钠通道阻滞剂。
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-80°C
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